Osteoarthritis of Knee
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Cannabidiol for Postoperative Opioid Reduction in Primary Total Knee Arthroplasty [Phase 2]
Phase 2 clinical trial evaluating cannabidiol to reduce postoperative opioid use after primary total knee arthroplasty. The study is current…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Liposomal Bupivacaine Versus Ropivacaine With Perineural Dexamethasone or Dexmedetomidine as Adjuncts for Adductor Canal Block Combined With IPACK Block in Total Knee Arthroplasty [NA]
An ongoing clinical trial is evaluating liposomal bupivacaine versus ropivacaine, combined with either perineural dexamethasone or dexmedeto…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Dexmedetomidine Intra Venous Arthroplasty [Phase 3]
Phase 3 trial evaluating intravenous dexmedetomidine as an adjunct during primary total knee arthroplasty has completed.
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Effect of Combined Adductor Canal and AFCN Block on Postoperative Inflammation
A clinical trial evaluating whether combining adductor canal and AFCN nerve blocks reduces postoperative inflammation after total knee arthr…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Intra-Articular Catheter Total Knee Arthroplasty [Phase 4]
Phase 4 trial update on an intra-articular catheter method for continuous local infiltration analgesia in total knee arthroplasty; enrollmen…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Functional Impact at 12 Months Post-op of Posterior Cruciate Ligament Conservation During Robotic-assisted Surgery (MAKO) for Total Knee Replacement. [NA]
This clinical trial assesses functional outcomes 12 months after posterior cruciate ligament-conserving, robotic-assisted total knee replace…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Surgeon Physiologic Stress During Unicompartmental Knee Arthroplasty: Manual vs Computer-Assisted Technique
A clinical trial comparing manual versus computer-assisted techniques for unicompartmental knee arthroplasty, focusing on surgeon physiologi…
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: Genicular Nerve Block Added to Femoral Nerve Block for Analgesia After Total Knee Arthroplasty [NA]
A completed clinical trial update indicates adding genicular nerve block to a femoral nerve block for analgesia after total knee arthroplast…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Study to Evaluate the Safety and Effectiveness of the REAL INTELLIGENCE™ CORI™ in Total Knee Arthroplasty (TKA) Procedure [NA]
Clinical trial evaluating the safety and effectiveness of the REAL INTELLIGENCE CORI system in total knee arthroplasty is currently recruiti…
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CLINICAL_TRIALS trial_result · 2026-03-10Clinical Trial Update: Systemic Lidocaine Versus Ultrasound-guided Adductor Canal Block for Patients Undergoing Total Knee Arthroplasty [Phase 4]
Phase 4 trial comparing systemic lidocaine to ultrasound-guided adductor canal block for perioperative analgesia in total knee arthroplasty …
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Determinants for Return to Work After Primary Knee Arthroplasty [NA]
A clinical trial exploring determinants of returning to work after primary knee arthroplasty (knee replacement) is currently active but not …
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Impact of Dexamethasone Route on Pain and Inflammation in iPACK With ACB for Knee Arthroplasty [Phase 4]
Phase 4 clinical trial investigating how the route of dexamethasone affects pain and inflammation in iPACK with adductor canal block for kne…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Minimal Sedation During Knee Replacement Surgery [NA]
An ongoing Mayo Clinic trial is evaluating minimal sedation during knee replacement surgery (Total Knee Arthroplasty) and is currently recru…
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: The Effect of Two Different Analgesic Methods on QoR-40 Score in Primary Unilateral Knee Arthroplasties [NA]
A completed clinical trial from Ataturk University comparing two analgesic methods and their effect on QoR-40 scores after primary unilatera…
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: Using a Smart Implantable Device to Compare Early Recovery in Two Different Knee Arthroplasty Approaches [NA]
A clinical trial evaluating a smart implantable device to compare early recovery between two knee arthroplasty approaches; recruitment has n…
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CLINICAL_TRIALS trial_result · 2026-01-16Clinical Trial Update: A Study to Evaluate Efficacy and Safety of AMZ001 for the Treatment of Knee Osteoarthritis Symptoms [Phase 3]
AMZ001 is being evaluated in a Phase 3 trial for knee osteoarthritis and the study is currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: Adductor Canal Block and IPACK Block vs Adductor Canal Block and the Gastrosoleus Interfascial Block After Total Knee Arthroplasty [NA]
This clinical trials registry entry describes a study comparing two anesthesia block strategies after total knee arthroplasty (adductor cana…
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CLINICAL_TRIALS trial_result · 2026-01-12Clinical Trial Update: Retrospective Simplex High Viscosity (HV) Bone Cement Study
A retrospective study evaluating Simplex HV Bone Cement for knee arthritis and aseptic loosening has completed and posted results.
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Hyperbaric Bupivacaine Versus Hyperbaric Prilocaine in Spinal Anaesthesia [Phase 4]
A Phase 4 clinical trial comparing hyperbaric bupivacaine versus hyperbaric prilocaine for spinal anesthesia in total knee arthroplasty is c…
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: Post-Operative Urinary Retention on Revision Knee Arthroplasty: the Role of Intrathecal Morphine [Phase 3]
A Phase 3 clinical trial evaluating whether intrathecal morphine reduces postoperative urinary retention in patients undergoing revision kne…
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CLINICAL_TRIALS trial_result · 2025-12-17Clinical Trial Update: The Role of Auricular Point Diagnosis and Treatment in ERAS During TKA
A completed clinical trial evaluated whether auricular point diagnosis and auriculotherapy integrated with Enhanced Recovery After Surgery i…
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CLINICAL_TRIALS trial_result · 2025-12-12Clinical Trial Update: Effect of Emotional Freedom Technique on Postoperative Pain and Anxiety in Patients Undergoing Total Knee Replacement [NA]
This clinical trial evaluated whether Emotional Freedom Technique reduces postoperative pain and anxiety in patients undergoing total knee a…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Cemented vs Cementless Persona Keel RCT [NA]
Clinical trial update showing an active but not recruiting randomized study comparing cemented versus cementless Persona Keel knee prosthese…
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: Adductor Under Sartorial Canal Catheter (KTT) Versus Femoral Catheter (KTF) in a Quick Rehabilitation Process After Total Knee Replacement [NA]
A completed clinical trial comparing adductor canal catheter (KTT) to femoral catheter (KTF) for a rapid rehabilitation process after total …
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CLINICAL_TRIALS trial_result · 2025-09-29Clinical Trial Update: A Post-Market, Retrospective Study on 3D Metal Tibial and Femoral Cones
This clinical trial update reports the completion of a post-market retrospective study evaluating 3D metal tibial and femoral cones used in …