Oral Leukoplakia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-06-22Clinical Trial Update: Topical Calcipotriol Versus Photodynamic Therapy in the Treatment of Oral Leukoplakia [Phase 2, Phase 3]
Clinical trial update comparing topical calcipotriol to photodynamic therapy for oral leukoplakia (Phase 2/Phase 3).
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Metformin for the Prevention of Oral Cancer in Patients With Oral Leukoplakia or Erythroplakia [Phase 2]
A Phase 2 clinical trial is evaluating metformin for prevention of oral cancer in patients with oral leukoplakia or erythroplakia; the study…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Low-cost Screening and Image-guided Photodynamic Therapy (PDT) of Premalignant and Malignant Oral Lesions [Phase 2]
This Phase 2 clinical trial update from the University of Massachusetts examines low-cost screening and image-guided photodynamic therapy fo…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Comparison of Topical Photodynamic Therapy With Topical Calcipotriol in Management of Oral Leukoplakia [Phase 3]
A Phase 3 clinical trial comparing topical photodynamic therapy with topical calcipotriol for managing oral leukoplakia, currently not yet r…
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CLINICAL_TRIALS trial_result · 2026-03-05Clinical Trial Update: Widefield Fluorescence and Reflectance Imaging Systems and Oral Tissue Samples in Monitoring Participants at Risk for Developing Oral Cancer [NA]
A clinical trial (NCT00542373) is evaluating widefield fluorescence and reflectance imaging systems and oral tissue samples to monitor indiv…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Topical Imiquimod Treatment of Oral Dysplasia [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating topical imiquimod for treating oral dysplasia and oral leukoplakia and is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-02-18Clinical Trial Update: Unveiling the Protein Expression Patterns in Oral Lichen Planus and Leukoplakia Through Comparative Salivary Proteomics
A completed clinical trial investigates salivary protein expression patterns in oral lichen planus and oral leukoplakia using comparative pr…
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CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: Evaluation of the Chemo-preventive Effect of Combined Topical and Systemic Metformin on Oral Leukoplakia [Phase 2]
A Phase 2 clinical trial is evaluating the chemo-preventive effect of combined topical and systemic metformin for oral leukoplakia. The stud…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Efficacy of Topical Coenzyme Q10 and Curcumin for Oral Leukoplakia Treatment [NA]
A clinical trial investigating the efficacy of topical coenzyme Q10 and curcumin for oral leukoplakia is currently recruiting.
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Evaluation of Artificial Intelligence in Diagnosis and Risk Assessment of Oral Potentially Malignant Disorders
This clinical trial evaluates the use of artificial intelligence to diagnose and assess risk for oral potentially malignant disorders, inclu…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: Pioglitazone-Metformin Combination Treatment for High Risk Oral Preneoplasia [Phase 2]
A Phase 2 clinical trial at the University of Minnesota is evaluating a pioglitazone-metformin combination for high-risk oral preneoplasia (…
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CLINICAL_TRIALS research · 2025-08-29Clinical Trial Update: Fenretinide Mucoadhesive Patch: Evaluation of Oral Cancer Prevention Efficacy in Adults With Premalignant Oral Lesions. [Phase 1]
Phase 1 clinical trial evaluating the safety and preliminary efficacy of a fenretinide mucoadhesive patch for preventing progression to oral…
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: Biomarkers for Oral Cancer
A completed clinical trial update from the National Cancer Institute focusing on biomarkers for oral cancer, including exploration in lichen…
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CLINICAL_TRIALS research · 2025-05-23Clinical Trial Update: SYsteMatical Trained learnIng aLgorithms for Oral carcInogenesiS Interpretation by Optical Coherence Tomography
A University of Palermo–sponsored clinical trial is recruiting to evaluate machine learning algorithms for interpreting oral carcinogenesis …
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CLINICAL_TRIALS trial_result · 2024-06-24Clinical Trial Update: Saliva and Plasma Exosomes for Oral Leukoplakia Malignant Transformation Diagnosis and Oral Cancer Prognosis Monitoring
This clinical trial examined saliva and plasma exosomes as diagnostic markers for malignant transformation in oral leukoplakia and for progn…
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CLINICAL_TRIALS trial_result · 2024-04-22Clinical Trial Update: Safety and Efficacy of Nivolumab in Treating Oral Proliferative Verrucous Leukoplakia [Phase 2]
Phase 2 clinical trial assessing nivolumab for safety and efficacy in oral proliferative verrucous leukoplakia has completed with results po…
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CLINICAL_TRIALS trial_result · 2019-05-23Clinical Trial Update: Metformin Hydrochloride in Preventing Oral Cancer in Patients With an Oral Premalignant Lesion [Phase 2]
Phase 2 trial evaluating metformin hydrochloride to prevent progression to oral cancer in patients with premalignant oral lesions (erythropl…
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CLINICAL_TRIALS trial_result · 2018-11-05Clinical Trial Update: Comparison or Rose Bengal and Toluidine Blue Staining for Lesion Detection Efficacy
A completed clinical trial comparing Rose Bengal and Toluidine Blue staining for detection of oral premalignant lesions, with posted results…
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CLINICAL_TRIALS trial_result · 2018-03-29Clinical Trial Update: Celecoxib in Preventing Cancer in Patients With Oral Leukoplakia and/or Head and Neck Dysplasia [Phase 2]
Phase 2 trial evaluating celecoxib for cancer prevention in patients with oral leukoplakia and/or head and neck dysplasia. The study status …
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CLINICAL_TRIALS trial_result · 2017-07-28Clinical Trial Update: Comparison Between Two Different High Power Ablative Lasers in the Treatment of Oral Leukoplakia [NA]
A completed clinical trial comparing two high-power ablative lasers for the treatment of oral leukoplakia, assessing outcomes and safety. Th…
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CLINICAL_TRIALS trial_result · 2017-05-17Clinical Trial Update: Photodynamic Therapy for Oral Precursor Lesions [Phase 3]
A Phase 3 clinical trial evaluating photodynamic therapy for oral precursor lesions has completed, including cases of oral leukoplakia and o…
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CLINICAL_TRIALS trial_result · 2016-08-01Clinical Trial Update: Tobacco Cessation Intervention Study for Oral Diseases [NA]
An update on a tobacco cessation intervention trial related to oral diseases, including periodontal disease, leukoplakia, lichen planus, and…
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CLINICAL_TRIALS trial_result · 2016-04-06Clinical Trial Update: Pioglitazone for Oral Premalignant Lesions [Phase 2]
Phase 2 trial evaluating pioglitazone for oral premalignant lesions (oral leukoplakia) was terminated, with results posted in 2016.
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CLINICAL_TRIALS trial_result · 2014-12-19Clinical Trial Update: Bowman-Birk Inhibitor Concentrate in Preventing Cancer in Patients With Oral Leukoplakia [Phase 2]
Phase 2 trial evaluating Bowman-Birk inhibitor concentrate to prevent cancer in patients with oral leukoplakia. The study is completed with …
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CLINICAL_TRIALS trial_result · 2014-10-09Clinical Trial Update: Photodynamic Therapy Using Aminolevulinic Acid in Treating Patients With Oral Leukoplakia [Phase 1]
Phase 1 trial evaluating photodynamic therapy with aminolevulinic acid for oral leukoplakia was terminated.