Oral Cavity Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-08-13Clinical Trial Update: Personalized Neck Radiation Therapy Directed by Sentinel Lymph Node Biopsy for the Treatment of Oral Cavity Squamous Cell Carcinoma, PRECEDENT Trial [Phase 2]
A Phase 2 clinical trial at the University of Michigan Rogel Cancer Center is evaluating personalized neck radiation therapy guided by senti…
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CLINICAL_TRIALS trial_result · 2025-06-27Clinical Trial Update: Testing the Addition of M6620 (VX-970, Berzosertib) to Usual Chemotherapy and Radiation for Head and Neck Cancer [Phase 1]
Phase 1 trial evaluating the addition of M6620 (berzosertib; VX-970) to standard chemotherapy and radiation for head and neck cancers, inclu…
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: Nivolumab and BMS986205 in Treating Patients With Stage II-IV Squamous Cell Cancer of the Head and Neck [Phase 2]
This is a Phase 2 clinical trial update examining nivolumab in combination with BMS986205 for stage II-IV squamous cell cancers of the head …
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CLINICAL_TRIALS trial_result · 2025-05-15Clinical Trial Update: Durvalumab With or Without Metformin in Treating Participants With Head and Neck Squamous Cell Carcinoma [EARLY_Phase 1]
Early-phase 1 clinical trial evaluating durvalumab with or without metformin in head and neck squamous cell carcinoma, including oral cavity…
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CLINICAL_TRIALS trial_result · 2025-03-17Clinical Trial Update: Durvalumab Before Surgery in Treating Patients With Oral Cavity or Oropharynx Cancer [EARLY_Phase 1]
Phase 1 trial evaluating durvalumab given before surgery in patients with oral cavity and/or oropharyngeal squamous cell carcinoma; the stud…
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CLINICAL_TRIALS withdrawal · 2025-02-14Clinical Trial Update: NT-I7 for the Treatment of Recurrent Squamous Cell Carcinoma of Head and Neck Undergoing Surgery [Phase 1]
A Phase 1 trial of NT-I7 for recurrent squamous cell carcinoma of the head and neck undergoing surgery was terminated.
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CLINICAL_TRIALS trial_result · 2025-02-11Clinical Trial Update: Onalespib in Treating Patients With Locoregionally Advanced Squamous Cell Carcinoma of the Head and Neck Receiving Radiation Therapy and Cisplatin [Phase 1]
Phase 1 trial evaluating the safety and tolerability of Onalespib in combination with radiation therapy and cisplatin for locoregionally adv…
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: Pembrolizumab & Cabozantinib in Patients With Head and Neck Squamous Cell Cancer [Phase 2]
Phase 2 trial evaluating the combination of pembrolizumab and cabozantinib in head and neck squamous cell carcinoma reported results, with r…
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CLINICAL_TRIALS trial_result · 2024-10-30Clinical Trial Update: Sentinel Node Biopsy in Early Oral Cancers a Tertiary Cancer Centre Experience [NA]
Completed clinical trial update from Tata Memorial Hospital describing sentinel lymph node biopsy in early oral cavity squamous cell carcino…
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CLINICAL_TRIALS trial_result · 2024-10-29Clinical Trial Update: Image-guided Proton Therapy for the Treatment of Locally Advanced Unresectable Head and Neck Cancer [Phase 1]
This Phase 1 trial update reports the completion of a study evaluating image-guided proton therapy for locally advanced unresectable head an…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: WEE1 Inhibitor with Cisplatin and Radiotherapy: a Trial in Head and Neck Cancer [Phase 1]
Phase 1 trial evaluating a WEE1 inhibitor in combination with cisplatin and radiotherapy for head and neck cancers has completed.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Neoadjuvant Sintilimab in Combination With Carboplatin and Nab-paclitaxel in Resectable Oral Cavity or Oropharyngeal Squamous Cell Carcinoma [Phase 2]
Phase 2 neoadjuvant trial evaluating sintilimab in combination with carboplatin and nab-paclitaxel for resectable oral cavity and oropharyng…
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Carboplatin Followed By Chemoradiation in Treating Patients With Recurrent Head and Neck Cancer [Phase 1]
Phase 1 trial of nab-paclitaxel (albumin-bound paclitaxel) with carboplatin followed by chemoradiation in patients with recurrent head and n…
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CLINICAL_TRIALS withdrawal · 2024-07-25Clinical Trial Update: Testing the Addition of an Investigational Drug, Xevinapant, to Usual Radiation Therapy Plus Cisplatin/Carboplatin for Patients With Head and Neck Cancer [Phase 2]
Phase 2 trial evaluating Xevinapant added to standard radiation therapy plus cisplatin/carboplatin for head and neck cancers has been withdr…
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CLINICAL_TRIALS research · 2024-07-03Clinical Trial Update: Durvalumab With or Without Tremelimumab in Resectable Locally Advanced Squamous Cell Carcinoma of the Oral Cavity [Phase 1, Phase 2]
Clinical trial update for a Phase 1/2 study of durvalumab with or without tremelimumab in resectable locally advanced oral cavity squamous c…
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CLINICAL_TRIALS trial_result · 2024-06-28Clinical Trial Update: Sodium Thiosulfate in Preventing Ototoxicity for Squamous Cell Cancer Patients Undergoing Chemoradiation With Cisplatin [Phase 2]
Phase 2 trial evaluating sodium thiosulfate to prevent cisplatin-induced ototoxicity in patients with head and neck squamous cell carcinoma …
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CLINICAL_TRIALS trial_result · 2024-06-20Clinical Trial Update: Postoperative CCRT With Docetaxel vs Cisplatin in High Risk Oral Cavity Cancer [Phase 2, Phase 3]
This trial compares postoperative concurrent chemoradiation with docetaxel versus cisplatin in high-risk oral cavity squamous cell carcinoma…
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CLINICAL_TRIALS research · 2024-05-17Clinical Trial Update: Neoadjuvant DaRT for Locally Advanced Oral Cavity SCC [NA]
A clinical trial update for neoadjuvant Diffusing Alpha-emitters Radiation Therapy (DaRT) in locally advanced oral cavity squamous cell carc…
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CLINICAL_TRIALS trial_result · 2024-04-01Clinical Trial Update: Nivolumab, Carboplatin, and Paclitaxel in Treating Patients With Stage III-IV Head and Neck Squamous Cell Carcinoma That Can Be Removed by Surgery [Phase 2]
A phase 2 trial evaluated the combination of nivolumab with carboplatin and paclitaxel in patients with stage III-IV head and neck squamous …
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CLINICAL_TRIALS trial_result · 2023-10-19Clinical Trial Update: Preoperative TPF Chemotherapy in Molecularly Selected Locally Advanced Resectable Oral Cavity Squamous Cell Cancer [Phase 2]
Phase 2 trial evaluating preoperative TPF chemotherapy in molecularly selected locally advanced resectable oral cavity squamous cell cancer …
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CLINICAL_TRIALS trial_result · 2023-03-08Clinical Trial Update: ACTOplus Met XR in Treating Patients With Stage I-IV Oral Cavity or Oropharynx Cancer Undergoing Definitive Treatment [Phase 2]
Phase 2 clinical trial update for ACTOplus Met XR in patients with stage I-IV oral cavity or oropharyngeal cancer undergoing definitive trea…
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CLINICAL_TRIALS trial_result · 2023-03-01Clinical Trial Update: A Study of Concurrent Chemoradiotherapy Based of Cisplatin With or Without Sintilimab as First-line Therapy for Patients With Advanced Oral Cavity Squamous Cell Carcinoma [Phase 2]
Phase 2 clinical trial evaluating concurrent chemoradiotherapy with cisplatin with or without sintilimab as first-line therapy for advanced …
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CLINICAL_TRIALS trial_result · 2022-12-14Clinical Trial Update: Comparison of Adaptive Dose Painting by Numbers With Standard Radiotherapy for Head and Neck Cancer. [Phase 2]
Phase 2 clinical trial comparing adaptive dose painting by numbers with standard radiotherapy for head and neck cancer has completed.
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CLINICAL_TRIALS trial_result · 2022-06-02Clinical Trial Update: Photodynamic Therapy With HPPH Compared to Standard of Care Surgery in Treating Patients With Oral Cavity Cancer [Phase 2]
Phase 2 trial comparing photodynamic therapy with HPPH to standard surgical care in stage I–II oral cavity squamous cell carcinoma was termi…
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CLINICAL_TRIALS trial_result · 2022-01-25Clinical Trial Update: Combination Chemotherapy With or Without Erlotinib Hydrochloride in Treating Patients With Metastatic or Recurrent Squamous Cell Carcinoma of the Head and Neck [Phase 2]
This Phase 2 trial evaluated chemotherapy with or without erlotinib in patients with metastatic or recurrent head and neck squamous cell car…