Optic Pathway Glioma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Evaluation of Hippocampal-Avoidance Using Proton Therapy in Low-Grade Glioma [NA]
Clinical trial evaluating hippocampal-avoidance using proton therapy in various low-grade gliomas; the study is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma [Phase 1, Phase 2]
Selumetinib is being studied in pediatric patients with recurrent or refractory low-grade glioma across Phase 1 and Phase 2 trials; the stud…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of the Drugs Selumetinib Versus Carboplatin/Vincristine in Patients With Neurofibromatosis and Low-Grade Glioma [Phase 3]
Phase 3 trial comparing selumetinib to carboplatin/vincristine in patients with neurofibromatosis type 1-associated low-grade glioma, with t…
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CLINICAL_TRIALS trial_result · 2026-03-19Clinical Trial Update: Safety and Efficacy of the PAINLESS Nerve Growth Factor CHF6467 in Optic Pathway Glioma (OPG) [Phase 2]
Phase 2 clinical trial update evaluating CHF6467, a nerve growth factor formulation, for safety and efficacy in patients with optic pathway …
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: A Study of Avutometinib for People With Solid Tumor Cancers [Phase 1]
A Phase 1 study of Avutometinib for people with solid tumors, including CNS tumors and NF1-associated tumors, is currently recruiting.
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CLINICAL_TRIALS research · 2024-10-15Clinical Trial Update: Modified CV Regimen in Optic Pathway Glioma [Phase 2]
Phase 2 clinical trial evaluating a modified CV regimen for optic pathway glioma in pediatric patients; currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-07-05Clinical Trial Update: A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas [Phase 1, Phase 2]
A Phase I/Phase II study evaluating mebendazole for pediatric gliomas has completed. It enrolled children with various glial tumors, includi…
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CLINICAL_TRIALS trial_result · 2022-01-24Clinical Trial Update: Pegylated Interferon ALFA-2b in Children With Juvenile Pilocytic Astrocytomas and Optic Pathway Gliomas [Phase 2]
Phase 2 trial assessing pegylated interferon alfa-2b in children with juvenile pilocytic astrocytoma and optic pathway gliomas has completed…
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CLINICAL_TRIALS trial_result · 2021-11-30Clinical Trial Update: Low-Dose or High-Dose Lenalidomide in Treating Younger Patients With Recurrent, Refractory, or Progressive Pilocytic Astrocytoma or Optic Pathway Glioma [Phase 2]
Phase 2 trial evaluating low-dose or high-dose lenalidomide in children with NF1-associated recurrent pilocytic astrocytoma or optic pathway…
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CLINICAL_TRIALS withdrawal · 2017-07-26Clinical Trial Update: Phase 3 Study of ANP Therapy vs. TMZ for Optic Pathway Glioma [Phase 3]
A Phase 3 clinical trial comparing ANP Therapy with temozolomide for optic pathway glioma has been withdrawn.
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CLINICAL_TRIALS trial_result · 2016-02-22Clinical Trial Update: Sorafenib in Children and Young Adults With Recurrent or Progressive Low-Grade Astrocytomas [Phase 2]
Phase 2 trial of sorafenib in children and young adults with recurrent or progressive low-grade astrocytomas, including patients with neurof…
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CLINICAL_TRIALS trial_result · 2014-02-20Clinical Trial Update: Cilengitide in Treating Younger Patients With Recurrent or Progressive High-Grade Glioma That Has Not Responded to Standard Therapy [Phase 2]
This Phase 2, NCI-sponsored trial evaluated cilengitide in children and adolescents with recurrent or progressive high-grade glioma refracto…