Opioid-induced Constipation
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-07-13Clinical Trial Update: To Evaluate Patient Preference of Movantik and Polyethylene Glycol 3350 for Opioid Induced Constipation [Phase 4]
Phase 4 trial comparing patient preference between Movantik (naloxegol) and polyethylene glycol 3350 for opioid-induced constipation; result…
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CLINICAL_TRIALS trial_result · 2018-05-22Clinical Trial Update: Use of MgSO4 for Pain After Bariatric Surgery [NA]
Completed clinical trial evaluating magnesium sulfate for pain relief after bariatric surgery, with the study related to opioid-induced cons…
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CLINICAL_TRIALS trial_result · 2018-03-08Clinical Trial Update: Study Evaluating Subcutaneous Methylnaltrexone For Treatment Of Opioid-Induced Constipation In Patients With Advanced Illness [Phase 4]
This document reports results from a Phase 4 study of subcutaneous methylnaltrexone for opioid-induced constipation in patients with advance…
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CLINICAL_TRIALS trial_result · 2018-03-07Clinical Trial Update: Safety of Subcutaneous Methylnaltrexone for Opioid-Induced Constipation in Patients With Advanced Illness [Phase 4]
A Phase 4 safety evaluation of subcutaneous methylnaltrexone for opioid-induced constipation in patients with advanced illness has completed…
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CLINICAL_TRIALS trial_result · 2017-08-30Clinical Trial Update: Effect of Naloxegol on Gastric, Small Bowel, and Colonic Transit in Healthy Subjects [Phase 1]
A Phase 1 study in healthy subjects evaluated the effects of naloxegol on gastric, small bowel, and colonic transit to characterize its impa…
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CLINICAL_TRIALS trial_result · 2017-05-30Clinical Trial Update: Efficacy and Safety of Naldemedine in the Treatment of Opioid-induced Constipation [Phase 3]
Phase 3 trial results evaluate the efficacy and safety of naldemedine for opioid-induced constipation. The trial was conducted by Shionogi a…
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CLINICAL_TRIALS trial_result · 2017-05-30Clinical Trial Update: Efficacy and Safety of Naldemedine in Treating Opioid-induced Constipation [Phase 3]
A Phase 3 clinical trial update reports on the efficacy and safety of naldemedine for treating opioid-induced constipation.
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CLINICAL_TRIALS trial_result · 2017-05-30Clinical Trial Update: A Study of Naldemedine (S-297995) for the Treatment of Opioid-Induced Constipation in Adults With Non-Malignant Chronic Pain Receiving Opioid Therapy [Phase 2]
Phase 2 trial results for Naldemedine (S-297995) in adults with opioid-induced constipation due to non-malignant chronic pain on opioid ther…
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CLINICAL_TRIALS trial_result · 2017-05-30Clinical Trial Update: Long Term Safety of Naldemedine [Phase 3]
Phase 3 long-term safety results for naldemedine in opioid-induced constipation were reported.
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CLINICAL_TRIALS trial_result · 2016-05-04Clinical Trial Update: A Single-arm, Study to Assess the Effect and Tolerability of Standardised Laxative Therapy (SLT) for the Reversal of Opioid-induced Constipation (OIC). [Phase 4]
Phase 4, single-arm trial completed to assess the effect and tolerability of Standardised Laxative Therapy (SLT) for reversing opioid-induce…
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CLINICAL_TRIALS trial_result · 2015-10-12Clinical Trial Update: Opioid Induced Bowel Dysfunction in Patients Undergoing Spinal Surgery [Phase 4]
This clinical trial update notes the completion of a Phase 4 study evaluating opioid-induced bowel dysfunction, focusing on constipation, in…
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CLINICAL_TRIALS trial_result · 2015-09-28Clinical Trial Update: Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation [Phase 3]
Phase 3 safety study of CB-5945 for opioid-induced constipation has been terminated with results posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-09-02Clinical Trial Update: Alvimopan For The Treatment Of Constipation Due To Opioids Being Taken For Persistent Non-Cancer Pain [Phase 3]
Phase 3 trial update of alvimopan (Entereg) for opioid-induced constipation in patients with persistent non-cancer pain; the study has compl…
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CLINICAL_TRIALS trial_result · 2015-09-02Clinical Trial Update: Treatment Of Constipation Due To Opioids Being Taken For Persistent Non-Cancer Pain [Phase 3]
Phase 3 clinical trial evaluating treatment for opioid-induced constipation in adults with persistent non-cancer pain has completed.
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CLINICAL_TRIALS trial_result · 2015-08-07Clinical Trial Update: Non-interventional Study Comparing Targiniq and Oxycodone/Laxatives
A completed non-interventional study comparing Targiniq (oxycodone/naloxone) to oxycodone plus laxatives in patients with pain and opioid-in…
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CLINICAL_TRIALS trial_result · 2015-07-29Clinical Trial Update: Enteral Naloxone Versus a Traditional Bowel Regimen for the Prevention of Opioid Induced Constipation in Trauma Patients [Phase 4]
Phase 4 trial comparing enteral naloxone to a traditional bowel regimen to prevent opioid-induced constipation in trauma patients; the study…
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CLINICAL_TRIALS trial_result · 2015-07-02Clinical Trial Update: Efficacy and Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation [Phase 3]
Phase 3 study of CB-5945 for opioid-induced constipation has terminated; results posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-06-17Clinical Trial Update: A 12-week Extension of the Phase III Study (D3820C00004) to Assess the Effect and Safety of NKTR-118 in Patients With Non-cancer-related Pain and Opioid-induced Constipation [Phase 3]
A 12-week extension of the Phase III study (D3820C00004) assessed the efficacy and safety of NKTR-118 for opioid-induced constipation in pat…
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CLINICAL_TRIALS trial_result · 2015-06-15Clinical Trial Update: Efficacy and Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation [Phase 3]
A Phase 3 trial update for CB-5945 in opioid-induced constipation has been terminated; results were posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-06-15Clinical Trial Update: The Efficacy and Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation [Phase 3]
Phase 3 trial of CB-5945 for opioid-induced constipation was terminated with posted results.
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CLINICAL_TRIALS trial_result · 2015-06-12Clinical Trial Update: A Phase 2, Double-Blind, Multiple-Dose Escalation Study to Evaluate NKTR-118 (Oral PEG-Naloxol) in Patients With Opioid-Induced Constipation (OIC) [Phase 2]
A Phase 2, double-blind, multiple-dose escalation study evaluated NKTR-118 (oral PEG-naloxol) for opioid-induced constipation, with results …
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CLINICAL_TRIALS trial_result · 2015-06-02Clinical Trial Update: Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation [Phase 3]
A Phase 3 trial by AstraZeneca evaluated the efficacy and safety of a treatment for opioid-induced constipation in patients with non-cancer-…
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CLINICAL_TRIALS trial_result · 2015-06-01Clinical Trial Update: Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation [Phase 3]
Phase 3 clinical trial assessing efficacy and safety of a treatment for opioid-induced constipation in patients with non-cancer-related pain…
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CLINICAL_TRIALS trial_result · 2015-06-01Clinical Trial Update: Assessment of Efficacy and Safety in Relieving Opioid-induced Constipation in Patients With Cancer-related Pain [Phase 3]
A Phase 3 trial evaluated efficacy and safety of a treatment for opioid-induced constipation in patients with cancer-related pain. The study…
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CLINICAL_TRIALS trial_result · 2015-05-19Clinical Trial Update: Methylnaltrexone Use for Opioid-induced Postoperative Constipation [Phase 4]
Phase 4 clinical trial update on Relistor (methylnaltrexone) for opioid-induced postoperative constipation. The study status is reported as …