Opioid Dependence
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-05-28Clinical Trial Update: Phone Interview to Prevent Recurring Opioid Overdoses [NA]
Completed clinical trial assessing a phone interview intervention to prevent recurrent opioid overdoses.
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CLINICAL_TRIALS trial_result · 2015-05-22Clinical Trial Update: Efficacy of BNX Sublingual Tablets Versus BNX Sublingual Film for Treatment of Opioid-Dependent Adults [Phase 3]
Phase 3 clinical trial comparing BNX Sublingual Tablets to BNX Sublingual Film in adults with opioid dependence on agonist therapy; results …
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CLINICAL_TRIALS trial_result · 2015-04-15Clinical Trial Update: Comparison of HIV Clinic-based Treatment With Buprenorphine Versus Referred Care in Heroin-dependent Participants [Phase 2]
Phase 2 trial comparing HIV clinic-based treatment with buprenorphine to referred care in heroin-dependent, HIV-infected participants; trial…
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CLINICAL_TRIALS trial_result · 2015-03-06Clinical Trial Update: Memantine-enhanced Buprenorphine Treatment for Opioid-dependent Young Adults [Phase 2, Phase 3]
Phase 2/3 trial of memantine-enhanced buprenorphine treatment for opioid dependence completed with results posted.
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CLINICAL_TRIALS trial_result · 2015-01-09Clinical Trial Update: Entry Into Comprehensive Methadone Treatment Via Interim Maintenance [NA]
This clinical trial update reports completion of a study evaluating entry into comprehensive methadone treatment using interim maintenance f…
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CLINICAL_TRIALS trial_result · 2014-09-12Clinical Trial Update: Computer-based Cognitive Behavioral Therapy for Risky Behaviors in Opioid Dependent Patients [NA]
Completed clinical trial evaluating computer-based cognitive behavioral therapy to reduce risky behaviors in patients with opioid dependence…
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CLINICAL_TRIALS trial_result · 2014-09-05Clinical Trial Update: Dronabinol Naltrexone Treatment for Opioid Dependence [Phase 2, Phase 3]
Phase 2 and Phase 3 trials evaluating a dronabinol-naltrexone combination for opioid dependence have completed, with results posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-08-22Clinical Trial Update: Completion of OST - a Prospective Study
Prospective study on opioid dependence has completed; results posted in 2014.
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FDA approval · 2014-01-07FDA Approved: VIVITROL — Supplemental Application (Alkermes, Inc.)
The FDA approved a supplemental application for VIVITROL (naltrexone long-acting injectable) submitted by Alkermes, Inc. The action updates/…
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CLINICAL_TRIALS trial_result · 2013-10-30Clinical Trial Update: Acute Effects of Cortisol on Heroin Craving in Opioid Dependence (Ghost-Basel) [Phase 2]
Phase 2 clinical trial examining whether cortisol acutely affects heroin craving in people with opioid dependence; the study has completed.
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CLINICAL_TRIALS withdrawal · 2013-07-04Clinical Trial Update: Naloxone Methadone Combination (NAMEKO) [NA]
A clinical trial evaluating a naloxone-methadone combination (NAMEKO) for opioid dependence has been withdrawn.
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CLINICAL_TRIALS trial_result · 2013-06-21Clinical Trial Update: Effects of Gabapentin Versus Placebo on Buprenorphine Detoxification of Opioid-dependent Individuals [Phase 2]
A Phase 2 randomized trial compared gabapentin to placebo to facilitate buprenorphine detoxification in opioid-dependent individuals; result…
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CLINICAL_TRIALS research · 2013-02-06Clinical Trial Update: An Assessment of Fentanyl Dose Requirements in Opioid-maintained Individuals [NA]
This document provides a clinical trial update evaluating fentanyl dose requirements in individuals maintained on opioids.
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CLINICAL_TRIALS trial_result · 2013-01-29Clinical Trial Update: Optimizing Outcomes Using Suboxone for Opiate Dependence [NA]
A UCLA-sponsored clinical trial evaluating Suboxone (buprenorphine/naloxone) for opioid dependence has completed, reporting on optimizing tr…
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CLINICAL_TRIALS trial_result · 2013-01-24Clinical Trial Update: Memantine and Naltrexone Treatment for Opioid Dependence [Phase 2]
Phase 2 clinical trial evaluating memantine in combination with naltrexone for opioid dependence; results were posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-01-23Clinical Trial Update: Pilot Study of Varenicline to Treat Opioid Dependence [Phase 1]
A Phase 1 pilot trial conducted at Mayo Clinic evaluated varenicline for treating opioid dependence. The study has completed.
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CLINICAL_TRIALS trial_result · 2012-12-28Clinical Trial Update: Pharmacogenetics of Disulfiram for Cocaine [Phase 2]
Phase 2 clinical trial evaluating the pharmacogenetics of disulfiram for cocaine dependence. The study included opioid dependence as a co-oc…
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CLINICAL_TRIALS trial_result · 2012-11-30Clinical Trial Update: Multicentre Trial of Suboxone in Opiate-dependent Subjects in Taiwan [Phase 4]
A multicentre Phase 4 trial of Suboxone (buprenorphine/naloxone) for opioid dependence in Taiwan has completed. The study was sponsored by I…
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CLINICAL_TRIALS trial_result · 2012-06-04Clinical Trial Update: Relapse Prevention to Reduce HIV Among Women Prisoners [Phase 4]
Phase 4 clinical trial update addressing relapse prevention to reduce HIV among women prisoners with opioid dependence; study completed with…
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CLINICAL_TRIALS trial_result · 2012-04-18Clinical Trial Update: Drug Discrimination in Methadone-Maintained Humans Study 2 [Phase 1]
Phase 1 clinical trial update of a drug-discrimination study in methadone-maintained individuals with opioid dependence. The study (Study 2)…
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CLINICAL_TRIALS trial_result · 2012-04-03Clinical Trial Update: SSRI and Buprenorphine [Phase 3]
Phase 3 trial of an SSRI in combination with buprenorphine for opioid dependence with comorbid depression has completed and results were pos…
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FDA approval · 2011-08-17FDA Approved: NALTREXONE HYDROCHLORIDE — Original Application (Accord Healthcare, Inc.)
FDA approved an original application for Naltrexone hydrochloride from Accord Healthcare, Inc., adding a generic option for the treatment of…
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CLINICAL_TRIALS trial_result · 2011-01-21Clinical Trial Update: ALK21-013: Efficacy and Safety of Medisorb® Naltrexone (VIVITROL®) in Adults With Opioid Dependence [Phase 3]
Phase 3 trial evaluating the efficacy and safety of Medisorb Naltrexone (VIVITROL) for adults with opioid dependence has completed. Results …
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CLINICAL_TRIALS trial_result · 2011-01-05Clinical Trial Update: Improving Methadone Maintenance Treatment Compliance and Outcomes in China [NA]
A completed clinical trial in China evaluating strategies to improve adherence and outcomes in methadone maintenance treatment for opioid de…
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FDA approval · 2010-10-12FDA Approved: VIVITROL — Supplemental Application (Alkermes, Inc.)
FDA approved a supplemental application for VIVITROL (naltrexone) by Alkermes, Inc., indicating an updated or expanded regulatory indication…