Onchocerciasis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-02-05Clinical Trial Update: Safety of a Single Dose of Moxidectin Compared With Ivermectin in Individuals Living in Onchocerciasis Endemic Areas and in Individuals Living in Onchocerciasis Endemic Areas With High Levels of Lymphatic Filariasis Co-endemicity Receiving Concomitant Albendazole [Phase 3]
Phase 3 trial comparing safety of a single dose of moxidectin versus ivermectin in people living in onchocerciasis-endemic areas, including …
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: Safety and Efficacy of Annual or Biannual Doses of Moxidectin or Ivermectin for Onchocerciasis [Phase 3]
A Phase 3 study is evaluating annual or biannual dosing of moxidectin or ivermectin for onchocerciasis, with the trial currently active but …
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CLINICAL_TRIALS trial_result · 2025-12-18Clinical Trial Update: Safety and Efficacy of Novel Combination Regimens for Treatment of Onchocerciasis [Phase 2]
Phase 2 trial evaluating the safety and efficacy of novel combination regimens for onchocerciasis; the study is currently active but not rec…
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CLINICAL_TRIALS trial_result · 2025-02-24Clinical Trial Update: Clinical Trial Evaluating the Safety and Efficacy of Moxidectin 2 mg Ivermectin-controlled in Loa Loa Microfilaremic Patients [Phase 2]
Phase 2 trial evaluating the safety and efficacy of moxidectin 2 mg in Loa loa microfilaremic patients with an ivermectin-controlled design;…
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: A Pharmacokinetic and Safety Study of Moxidectin to Identify an Optimal Dose for Treatment of Children 4 to 11 Years [Phase 1]
Phase 1 pharmacokinetic and safety study of moxidectin in children aged 4 to 11 years to identify an optimal dose for treating onchocerciasi…
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CLINICAL_TRIALS trial_result · 2024-09-27Clinical Trial Update: A Study to Learn About How Much Emodepside Gets Absorbed in the Blood and How Food Affects Its Absorption When Given as a New Type of Tablet to Healthy Participants [Phase 1]
Phase 1 study to characterize the pharmacokinetics of emodepside and the effect of food on its absorption in healthy participants.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Study to Assess Adverse Events, Change in Disease Activity and How Oral ABBV-4083 Capsules When Given Alone or In Combination With Albendazole Capsules Moves in The Body of Adult Participants With Onchocerca Volvulus Infection [Phase 2]
Phase 2 trial evaluating ABBV-4083 alone or with albendazole for onchocerciasis; the study was terminated but results were posted in 2024, i…
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: Clinical Trial of Rifampin and Azithromycin for the Treatment of River Blindness [Phase 2]
A Phase 2 CDC-sponsored trial evaluating rifampin in combination with azithromycin for Onchocerciasis has completed.
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CLINICAL_TRIALS trial_result · 2024-03-05Clinical Trial Update: Emodepside Phase II Trial for Treatment of Onchocerciasis [Phase 2]
A Phase II clinical trial of emodepside for treating onchocerciasis is currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2023-05-10Clinical Trial Update: Safety and Efficacy of IDA for Onchocerciasis [Phase 2]
A Phase 2 clinical trial evaluating the safety and efficacy of IDA (Ivermectin, Diethylcarbamazine, and Albendazole) for Onchocerciasis has …
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CLINICAL_TRIALS trial_result · 2022-12-15Clinical Trial Update: Study Evaluating Orally Administered Moxidectin In Subjects With Onchocerca Volvulus Infection [Phase 2]
Phase 2 trial update evaluating orally administered moxidectin for Onchocerciasis has completed.
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CLINICAL_TRIALS trial_result · 2019-04-26Clinical Trial Update: Efficacy of Ivermectin and Albendazole Against Onchocerciasis in the Volta Region, Ghana [Phase 3]
Phase 3 clinical trial evaluating the efficacy of ivermectin and albendazole against onchocerciasis in the Volta Region, Ghana has completed…
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CLINICAL_TRIALS trial_result · 2018-05-04Clinical Trial Update: Optimization of Mass Drug Administration With Existing Drug Regimens for Lymphatic Filariasis and Onchocerciasis for Ivory Coast (DOLF-Ivory Coast)
This clinical trial update describes efforts to optimize mass drug administration regimens for lymphatic filariasis and onchocerciasis in Iv…
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CLINICAL_TRIALS trial_result · 2018-01-31Clinical Trial Update: Study Comparing Moxidectin And Ivermectin In Subjects With Onchocerca Volvulus Infection [Phase 3]
Phase 3 trial comparing moxidectin and ivermectin for onchocerciasis has completed.
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CLINICAL_TRIALS trial_result · 2017-08-29Clinical Trial Update: IVM Alone vs ALB + IVM Against Onchocerciasis [Phase 3]
A Phase 3 trial comparing ivermectin alone versus albendazole plus ivermectin for onchocerciasis has completed.