Ocular Surface Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: The Efficacy of Intradermal Acupuncture for Ocular Surface Diseases After Intractable Facial Paralysis [NA]
A clinical trial update notes recruitment for a study evaluating intradermal acupuncture for ocular surface diseases in patients with intrac…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Effect of Acoltremon Ophthalmic Solution 0.003% on Signs and Symptoms of Ocular Surface Disease in Stage I Neurotrophic Keratopathy Patients With Tear Deficiency [Phase 4]
Phase 4 clinical trial evaluating Acoltremon ophthalmic solution 0.003% for signs and symptoms of ocular surface disease in patients with St…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: This is a Single Center, Open-label Prospective Study to Evaluate the Effect of Xiidra® (Lifitegrast Ophthalmic Solution 5.0%) on Tear Film Biomarkers in Dry Eye [Phase 4]
Phase 4 open-label prospective study at a single center to evaluate the effect of Lifitegrast (Xiidra) 5% ophthalmic solution on tear film b…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Treatment of Ocular Discomfort in Glaucoma Patients Using Multiple Topical Medications
A clinical trial is assessing the treatment of ocular discomfort in glaucoma patients using multiple topical medications. The study is curre…
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CLINICAL_TRIALS trial_result · 2026-01-29Clinical Trial Update: Safety of Topical Mesenchymal Stromal Cell Secretome for Ocular Surface Disease [EARLY_Phase 1]
A Phase 1 study assessed the safety of topical mesenchymal stromal cell secretome for ocular surface disease. The trial has completed.
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CLINICAL_TRIALS trial_result · 2026-01-02Clinical Trial Update: Effect of Low-Level Light Therapy on Ocular Surface Parameters in Patients Undergoing Cataract Surgery [NA]
Clinical trial completed evaluating the effect of low-level light therapy on ocular surface parameters in patients undergoing cataract surge…
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CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: Eyelid Closure in Keratometry [NA]
A clinical trial sponsored by the Vienna Institute for Research in Ocular Surgery is recruiting for a study on eyelid closure in keratometry…
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CLINICAL_TRIALS trial_result · 2025-11-17Clinical Trial Update: Effect of Four Different Diagnostic Eye Drops on Tear Film Thickness [Phase 3]
Phase 3 trial evaluating four diagnostic eye drops for their effect on tear film thickness has completed.
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CLINICAL_TRIALS trial_result · 2025-09-25Clinical Trial Update: Effect of Low-Level Light Therapy on Ocular Surface Parameters in Patients Undergoing Femto-Lasik Surgery [NA]
A completed clinical trial evaluated the effect of low-level light therapy on ocular surface parameters in patients undergoing femto-LASIK s…
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CLINICAL_TRIALS trial_result · 2025-06-03Clinical Trial Update: The Effect of Eye Care With Artificial Tears and Normal Saline on Ocular Surface Disease in Mechanically Ventilated Pediatric Patients [NA]
The completed trial evaluated the effect of eye care with artificial tears and normal saline on ocular surface disease in mechanically venti…
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CLINICAL_TRIALS research · 2025-03-19Clinical Trial Update: Study to Evaluating PRO-240 Ophthalmic Solution Compared to Optive® [Phase 1]
Phase 1 clinical trial evaluating PRO-240 ophthalmic solution compared with Optive for dry eye disease; the study is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-03-06Clinical Trial Update: Effects of HFMH-EMS on Ocular Artery Circulation [NA]
A completed clinical trial from Chung Shan Medical University evaluating the effects of HFMH-EMS on ocular artery circulation.
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CLINICAL_TRIALS trial_result · 2025-03-04Clinical Trial Update: Cool vs Room-temperature Artificial Tears [Phase 4]
Phase 4 clinical trial comparing cool versus room-temperature artificial tears has completed; results have been posted.
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CLINICAL_TRIALS other · 2025-03-04Clinical Trial Update: Clinical Study to Evaluate the Safety and Tolerability of PRO-229 Ophthalmic Solution Compared to Lagricel® Ofteno PF [Phase 1]
Phase 1 clinical trial evaluating the safety and tolerability of PRO-229 ophthalmic solution versus Lagricel Ofteno PF for Dry Eye Disease a…
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CLINICAL_TRIALS trial_result · 2025-01-13Clinical Trial Update: Novel Use of Cyclosporine Ophthalmic Emulsion 0.05% in a PROSE Device [Phase 1, Phase 2]
A Phase 1/2 trial assessed cyclosporine ophthalmic emulsion 0.05% delivered with a PROSE device for ocular surface disease; results have bee…
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CLINICAL_TRIALS research · 2024-12-05Clinical Trial Update: Analysis of Videodermatoscopic Parameters of Ocular, Periocular, Conjunctival and Palpebral Neoformations
A clinical study updating on the analysis of videodermatoscopic parameters of ocular and periocular neoformations, with recruitment ongoing …
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CLINICAL_TRIALS trial_result · 2024-10-03Clinical Trial Update: Efficacy and Safety of Topical Cyclosporine 0.05% and Lifitgrast on the Ocular Surface Symptom After Photorefractive Keratectomy in Feiz Hospital, Isfahan, 2024 [Phase 1]
Phase 1 trial evaluating the safety and efficacy of topical cyclosporine 0.05% and lifitegrast for ocular surface symptoms after photorefrac…
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CLINICAL_TRIALS research · 2024-08-15Clinical Trial Update: Clinical Application Research of Scleral Lenses in Ocular Surface Diseases
A clinical trial evaluating scleral lenses for ocular surface diseases is currently recruiting. The study is sponsored by the Second Affilia…
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CLINICAL_TRIALS research · 2024-07-10Clinical Trial Update: Comparison Between Lathe Cut Versus Cast Molding Soft Contact Lens Technique on Ocular Surface Integrity [NA]
A clinical trial comparing lathe-cut versus cast-molded soft contact lens fabrication techniques to evaluate ocular surface integrity in ocu…
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CLINICAL_TRIALS research · 2024-06-20Clinical Trial Update: Investigator-initiated Clinical Trial to Observe Conjunctival Goblet Cell Using an Anterior Segment Imaging Device [NA]
An investigator-initiated clinical trial at Seoul National University Hospital is observing conjunctival goblet cells using an anterior segm…
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CLINICAL_TRIALS trial_result · 2024-05-28Clinical Trial Update: A Phase III Multinational Multicenter Investigator-Masked Randomized Active-Controlled Trial Comparing the Efficacy and Safety of DE-130A With Xalatan® in Patients With Open-Angle Glaucoma or Ocular Hypertension [Phase 3]
Phase III multinational, investigator-masked, active-controlled trial comparing DE-130A with Xalatan (latanoprost) in open-angle glaucoma or…
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CLINICAL_TRIALS trial_result · 2024-05-08Clinical Trial Update: A Comparative Study Between Preservative With Benzalkonium Chloride vs Preservative Free Eye Drops on the Ocular Surface [Phase 4]
Phase 4 clinical trial comparing benzalkonium chloride–preserved eye drops with preservative-free eye drops to evaluate effects on the ocula…
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CLINICAL_TRIALS trial_result · 2023-10-27Clinical Trial Update: Pilot Study to Investigate the Feasibility, Reliability and Efficacy of Utilizing OCT to Automate PROSE Fitting [NA]
Pilot study assessing feasibility and reliability of using OCT to automate PROSE fitting, with completed status and posted results.
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CLINICAL_TRIALS withdrawal · 2023-04-19Clinical Trial Update: Novel Use of Restasis and PROSE Devices [Phase 3]
A Phase 3 trial investigating a novel use of Restasis and PROSE devices for ocular surface disease was withdrawn.
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CLINICAL_TRIALS trial_result · 2023-03-24Clinical Trial Update: Amelioration of Adverse Ocular Side Effects of Glaucoma Medications in Glaucoma Patients Using Topical GL101 [Phase 2]
Phase 2 trial update on GL101 aiming to reduce adverse ocular side effects from glaucoma medications in glaucoma patients.