Ocular Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-02Clinical Trial Update: Proof of Concept of TBio-4101, Lymphodepleting Chemo, IL-2 for Relapsed/Refractory Melanoma [Phase 1]
Phase 1 trial update reports proof of concept for TBio-4101 in combination with lymphodepleting chemotherapy and IL-2 for relapsed/refractor…
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CLINICAL_TRIALS trial_result · 2026-04-01Clinical Trial Update: iSITE: Investigation of Somatic Alterations in Tumours of the Eye
The iSITE trial from The Wellcome Sanger Institute investigates somatic alterations in ocular melanoma and has completed.
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CLINICAL_TRIALS trial_result · 2026-04-01Clinical Trial Update: Olaparib in Combination With Pembrolizumab for Advanced Uveal Melanoma [Phase 2]
A Phase 2 clinical trial is evaluating olaparib in combination with pembrolizumab for advanced uveal/ocular melanoma, currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-13Clinical Trial Update: Imatinib in Adult Patients With Metastatic Ocular Melanoma [Phase 2]
A Phase 2 trial of imatinib in adults with metastatic ocular melanoma has been terminated.
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CLINICAL_TRIALS trial_result · 2026-03-02Clinical Trial Update: A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham Control in Subjects With Primary Indeterminate Lesions or Small Choroidal Melanoma [Phase 3]
Phase 3 randomized trial in recruitment evaluating Belzupacap Sarotalocan (AU-011) versus sham control for primary indeterminate lesions or …
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Choroidal Melanoma Patient-Reported Outcome Study (CM-PRO) in a Subset of AU-011-301 (CoMpass) Subjects
A patient-reported outcome study (CM-PRO) is being conducted in a subset of AU-011-301 (CoMpass) trial participants, with recruitment ongoin…
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: Eye Plaque Brachytherapy for Ocular Melanoma
This clinical trial update concerns eye plaque brachytherapy for ocular melanoma; the study is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-05-28Clinical Trial Update: Resistance Exercise in Patients With Ocular Melanoma [NA]
A University of Valencia-sponsored clinical trial is evaluating resistance exercise in patients with ocular melanoma. The study is currently…
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CLINICAL_TRIALS other · 2025-04-09Clinical Trial Update: THE IPI - Trial in Advanced Melanoma: Melanoma Patients With Advanced Disease [Phase 2]
Phase 2 trial titled THE IPI - Trial in Advanced Melanoma studied ocular melanoma; the study status is COMPLETED.
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CLINICAL_TRIALS trial_result · 2024-11-05Clinical Trial Update: Hepatic Ablation of Melanoma Metastases to Enhance Immunotherapy Response, a Phase I Clinical Trial (HAMMER I) [Phase 1]
HAMMER I is a Phase I trial evaluating hepatic ablation of melanoma liver metastases to enhance response to immunotherapy; the study status …
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FDA approval · 2024-05-22FDA Approved: HEPZATO KIT — Supplemental Application (Delcath Systems, Inc.)
The FDA approved a supplemental application for Hepzato Kit, a melphalan hydrochloride lyophilized injection, used with hepatic perfusion to…
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CLINICAL_TRIALS trial_result · 2024-04-05Clinical Trial Update: Neoadjuvant and Adjuvant Checkpoint Blockade [Phase 2]
A Phase 2 neoadjuvant and adjuvant checkpoint blockade trial in melanoma completed with results posted in 2024.
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CLINICAL_TRIALS trial_result · 2024-02-01Clinical Trial Update: Study in Subjects With Small Primary Choroidal Melanoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial in subjects with small primary choroidal melanoma (uveal/ocular melanoma) has completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-12-21Clinical Trial Update: Percutaneous Hepatic Perfusion in Patients With Hepatic-dominant Ocular Melanoma [Phase 3]
Phase 3 trial update for Percutaneous Hepatic Perfusion in hepatic-dominant ocular melanoma has completed.
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CLINICAL_TRIALS trial_result · 2023-12-21Clinical Trial Update: An Open-Label Expanded Access Study of the Melphalan/Hepatic Delivery System (HDS) in Patients With Hepatic Dominant Ocular Melanoma [Phase 3]
Open-label expanded access study update for the Melphalan/Hepatic Delivery System in hepatic-dominant ocular/uveal melanoma (Phase 3).
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CLINICAL_TRIALS trial_result · 2023-04-11Clinical Trial Update: Study of Adjuvant Ipilimumab and Nivolumab in Subjects With High-risk Ocular Melanoma [Phase 2]
Phase 2 trial evaluating adjuvant ipilimumab and nivolumab in high-risk ocular melanoma.
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CLINICAL_TRIALS trial_result · 2018-11-02Clinical Trial Update: Study With T-cel Receptor Gene Therapy in Metastatic Melanoma [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating a T-cell receptor gene therapy for metastatic melanoma, including stage IV skin melanoma and ocular me…
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CLINICAL_TRIALS trial_result · 2018-06-27Clinical Trial Update: STA-9090(Ganetespib) in Metastatic Ocular Melanoma [Phase 2]
Phase 2 trial of ganetespib (STA-9090) in metastatic ocular melanoma has been completed with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-04-23Clinical Trial Update: Sorafenib and Radioembolization With Sir-Spheres® for the Treatment of Metastatic Ocular Melanoma [Phase 1]
Phase 1 trial update evaluating the combination of sorafenib with Sir-Spheres Y-90 radioembolization for metastatic ocular melanoma; the stu…
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CLINICAL_TRIALS trial_result · 2017-07-24Clinical Trial Update: Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Ocular Melanoma [Phase 2]
Phase 2 trial evaluating tumor-infiltrating lymphocytes (TIL) immunotherapy for metastatic ocular/uveal melanoma; study terminated with resu…
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CLINICAL_TRIALS trial_result · 2016-07-07Clinical Trial Update: Combined PET/CT Imaging for the Early Detection of Ocular Melanoma Metastasis Compared to CT Scanning Alone
A completed trial comparing combined PET/CT imaging to CT alone for early detection of ocular melanoma metastasis.
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CLINICAL_TRIALS trial_result · 2015-10-02Clinical Trial Update: Interferon Beta in Treating Patients With Metastatic Cutaneous Melanoma or Ocular Melanoma [Phase 2]
A Phase 2 trial evaluating interferon beta in patients with metastatic cutaneous melanoma or ocular melanoma has completed.
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CLINICAL_TRIALS withdrawal · 2013-12-02Clinical Trial Update: Investigative Trial of Interferon Alpha-2b To Shrink Cancer of the Eye [NA]
An investigative trial of interferon alpha-2b for ocular melanoma has been withdrawn.
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CLINICAL_TRIALS trial_result · 2013-10-23Clinical Trial Update: Expanded Access Study of Melphalan With Delcath CS-PHP System in Patients With Ocular/Cutaneous Melanoma Mets to Liver
Expanded-access study of melphalan with the Delcath CS-PHP system for liver metastases from ocular or cutaneous melanoma is no longer availa…
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CLINICAL_TRIALS trial_result · 2012-08-20Clinical Trial Update: A Phase II Study of Isolated Hepatic Perfusion (IHP) in Patients With Ocular Melanoma [Phase 2]
Phase II study evaluating isolated hepatic perfusion for ocular melanoma has completed.