Ocular Graft-versus-host Disease
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Study of d-MAPPS™ Ophthalmic Solution, Safety, Tolerability, and Efficacy in the Treatment of Chronic Ocular Graft-Versus-Host Disease (oGVHD) [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the safety, tolerability, and efficacy of d-MAPPS Ophthalmic Solution for chronic ocular graft-versus-…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: 2177GCCC:ID'Ing tx Targets and Biomarkers for Ocular Surface Disease in Pt w/ oGVHD
A clinical trial update for an ongoing study evaluating targets and biomarkers for ocular surface disease in patients with ocular graft-vers…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: A PHASE II PROSPECTIVE RANDOMIZED DOUBLE-MASKED CROSSOVER STUDY ASSESSING THE SAFETY & EFFICACY OF RHPRG4 (450 μG/ML RECOMBINANT HUMAN PROTEOGLYCAN 4) COMPARED TO VEHICLE FOR THE TREATMENT OF OCULAR GRAFT-VERSUS-HOST DISEASE (OGVHD) [Phase 2]
A Phase II prospective randomized double-masked crossover trial is evaluating the safety and efficacy of RHPRG4 for ocular graft-versus-host…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Electrostimulation Study for Ocular Graft vs. Host Disease [NA]
Clinical trial update describing an electrostimulation study for chronic ocular graft-versus-host disease. The study is currently recruiting…
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CLINICAL_TRIALS research · 2025-10-23Clinical Trial Update: The Prevalence of Hypoesthesia Related Keratitis in Ocular Graft Vs. Host Disease (GVHD) Patients
Indiana University is conducting a study to determine how common hypoesthesia-related keratitis is in patients with ocular graft-versus-host…
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CLINICAL_TRIALS research · 2025-05-08Clinical Trial Update: A Study of Stem Cells Lenses in the coGVHD Subjects [EARLY_Phase 1]
This clinical trial update describes a Phase 1 study of stem cell lenses for chronic ocular graft-versus-host disease, which is currently no…
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CLINICAL_TRIALS research · 2024-05-14Clinical Trial Update: Validation of Human Drugs Target of Repurposed Drugs and Novel Therapies
This update outlines a clinical trial on validating human drug targets for repurposed drugs and novel therapies, focusing on ocular diseases…