Norovirus Infection
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: A Study to Evaluate the Efficacy, Safety and Pharmacokinetics of CDI-988 in Healthy Adults After Challenge With Snow Mountain Virus [Phase 1, Phase 2]
This update states that CDI-988 is being evaluated for efficacy, safety, and pharmacokinetics in healthy adults after a norovirus challenge …
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Adoptive T Lymphocyte Administration for Chronic Norovirus Treatment in Immunocompromised Hosts [Phase 1]
Phase 1 clinical trial evaluating adoptive T lymphocyte therapy to treat chronic norovirus infection in immunocompromised patients is curren…
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CLINICAL_TRIALS trial_result · 2026-01-16Clinical Trial Update: Phase III Clinical Trial to Evaluate the Human Norovirus Bivalent (GⅠ.1/GⅡ.4)Vaccine，Recombinant (Hansenula Polymorpha) [Phase 3]
Phase III trial evaluating a recombinant human norovirus bivalent GI.1/GII.4 vaccine completed, sponsored by the National Vaccine and Serum …
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CLINICAL_TRIALS trial_result · 2025-05-06Clinical Trial Update: Norovirus Challenge Study [Phase 1, Phase 2]
Vaxart completed a Phase 1/2 Norovirus challenge study and posted results in May 2025.
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CLINICAL_TRIALS trial_result · 2025-04-15Clinical Trial Update: A Study to Determine the Safety and Immunogenicity of Bivalent GI.1 and GII.4 Vaccines in Healthy Volunteers [Phase 2]
Phase 2 trial evaluating safety and immunogenicity of a bivalent GI.1/GII.4 norovirus vaccine in healthy volunteers; results have been poste…
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CLINICAL_TRIALS trial_result · 2024-06-21Clinical Trial Update: A Phase 1, Open-label, Safety and Immunogenicity Study of an Oral Multi-dose Administration Regimen With an Adenoviral-vector Based Tablet Norovirus Vaccine (VXA-G1.1-NN) Administered to Healthy Adult Volunteers [Phase 1]
This Phase 1 open-label trial evaluated safety and immunogenicity of VXA-G1.1-NN, an oral multi-dose adenoviral-vector Norovirus vaccine, in…
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CLINICAL_TRIALS trial_result · 2024-05-22Clinical Trial Update: Immunogenicity & Safety Study of Adenovirus Type 5 (AD5) Based Oral Norovirus Vaccines [Phase 1, Phase 2]
Update on a Phase 1/2 study of an adenovirus type 5–based oral norovirus vaccine from Vaxart, reporting immunogenicity and safety results; t…
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CLINICAL_TRIALS trial_result · 2021-06-10Clinical Trial Update: Efficacy and Immunogenicity of Norovirus GI.1/GII.4 Bivalent Virus-like Particle Vaccine in Adults [Phase 2]
Phase 2 trial update evaluating the efficacy and immunogenicity of a bivalent Norovirus VLP vaccine (GI.1/GII.4) in adults.
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CLINICAL_TRIALS trial_result · 2020-01-22Clinical Trial Update: Evaluation of Infectivity and Illness of Norwalk GI.1 Virus Lot 001-09NV in the Human Challenge Model [Phase 1]
Phase 1 study evaluating infectivity and illness of Norwalk GI.1 virus in a human challenge model has completed with results posted.
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CLINICAL_TRIALS trial_result · 2017-08-08Clinical Trial Update: Norwalk Vaccine Study [Phase 1, Phase 2]
Takeda's Norovirus vaccine study, a Phase 1/2 trial for acute gastroenteritis and Norovirus infection, has completed.
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CLINICAL_TRIALS trial_result · 2017-02-23Clinical Trial Update: Safety and Immunogenicity of Norovirus Bivalent Virus-Like Particle Vaccine in Healthy Adults [Phase 2]
Phase 2 trial evaluating safety and immunogenicity of Takeda's Norovirus Bivalent Virus-Like Particle Vaccine in healthy adults; results wer…
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CLINICAL_TRIALS trial_result · 2016-10-28Clinical Trial Update: Serologic Assay Validation, Proficiency Testing, Safety and Immunogenicity of Norovirus GI.1/GII.4 Bivalent Virus-Like Particle Vaccine [Phase 2]
Phase 2 trial evaluating serologic assay validation, proficiency testing, safety and immunogenicity of a norovirus GI.1/GII.4 bivalent VLP v…
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CLINICAL_TRIALS trial_result · 2016-08-15Clinical Trial Update: Norovirus Bivalent-Vaccine Efficacy Study [Phase 1, Phase 2]
Phase 1/2 trial update for a norovirus bivalent vaccine assessing prevention of norovirus infection; results posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-08-01Clinical Trial Update: Safety and Immunogenicity of Norovirus GI.1/GII.4 Bivalent VLP Vaccine [Phase 2]
Phase 2 study evaluating safety and immunogenicity of Takeda's norovirus GI.1/GII.4 bivalent virus-like particle vaccine in healthy voluntee…
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CLINICAL_TRIALS trial_result · 2015-05-06Clinical Trial Update: Phase 1 Norwalk Vaccine Study [Phase 1]
Phase 1 clinical trial of the Norovirus (Norwalk) vaccine developed by LigoCyte Pharmaceuticals has completed.
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CLINICAL_TRIALS trial_result · 2014-05-07Clinical Trial Update: Dose Range Evaluation of Norovirus Challenge Pool (GII.4, CIN-1) [Phase 1]
Phase 1 dose-range study evaluating a Norovirus GII.4 CIN-1 challenge pool; completed.
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CLINICAL_TRIALS trial_result · 2012-05-31Clinical Trial Update: Study of Nitazoxanide Suspension in the Treatment of Diarrhea Caused by Enteric Viruses in Children [Phase 2, Phase 3]
This document notes the completed Phase 2/Phase 3 trial of nitazoxanide suspension for diarrhea caused by enteric viruses in children, inclu…
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CLINICAL_TRIALS trial_result · 2012-02-10Clinical Trial Update: Susceptibility of Human Volunteers With Different Histo-Blood With Different Histo-Blood Group Antigens to Norovirus [Phase 1]
Phase 1 study in healthy adults evaluated whether different histo-blood group antigen types influence susceptibility to Norovirus infection.…