Normal Pressure Hydrocephalus
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Normal Pressure Hydrocephalus and Sleep Apnea [NA]
A University of Valencia-sponsored trial is investigating Normal Pressure Hydrocephalus and Sleep Apnea; the study is currently RECRUITING, …
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CLINICAL_TRIALS other · 2026-04-22Clinical Trial Update: CSF Protein Markers as Prognostic Indicators of the Response to CSF Shunt in Normotensive Hydrocephalus
A clinical trial evaluating CSF protein markers as predictors of response to CSF shunt in normal pressure hydrocephalus. The study is curren…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Examining the Feasibility of Using Pressure Gradient Regulated Automated Cerebral Spinal Fluid Drainage During External Lumbar Drain Trials [NA]
This clinical trial update describes a feasibility study on using pressure gradient regulated automated CSF drainage during external lumbar …
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: White Matter Distortion and Dementia Biomarkers in Normal Pressure Hydrocephalus (NPH)
Recruiting ongoing for a study at Imperial College London investigating white matter distortion and biomarkers of dementia in Normal Pressur…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Pilot Study of the CereVasc® eShunt® System in Normal Pressure Hydrocephalus [NA]
Pilot study update on CereVasc eShunt System for Normal Pressure Hydrocephalus; the trial is currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: Post Market Clinical Follow-up of CODMAN CERTAS Programmable Valve
This Clinical Trial Update describes a post-market clinical follow-up study of the CODMAN CERTAS Programmable Valve for hydrocephalus and re…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Evaluation of the Safety and Effectiveness of the CereVasc® eShunt® System in Normal Pressure Hydrocephalus [NA]
Clinical trial evaluating the safety and effectiveness of the CereVasc eShunt System for normal pressure hydrocephalus is currently recruiti…
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CLINICAL_TRIALS trial_result · 2026-02-11Clinical Trial Update: The Role of the Glymphatic System Avaluated Thourgh mr Imaging in the Diagnosis and Management of NPH
A completed clinical trial evaluating whether MRI-based assessment of the glymphatic system can aid in the diagnosis and management of norma…
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CLINICAL_TRIALS trial_result · 2025-12-15Clinical Trial Update: Cerebrospinal Fluid Proteome in Hydrocephalus [NA]
This document reports the completion of a clinical trial studying the cerebrospinal fluid proteome in normal pressure hydrocephalus.
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CLINICAL_TRIALS trial_result · 2025-09-19Clinical Trial Update: Predictive Value of Flow MRI in Normal Pressure Hydrocephalus Surgery [EARLY_Phase 1]
Completed early-phase study evaluating whether flow MRI can predict outcomes of surgery for normal pressure hydrocephalus. Results may infor…
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: Non-invasive Diagnostics of Shunt Obstruction in Adult Hydrocephalus [NA]
This clinical trial update describes a non-invasive diagnostic study for shunt obstruction in adults with normal pressure hydrocephalus. The…
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CLINICAL_TRIALS research · 2025-06-19Clinical Trial Update: US Pilot Study of the CereVasc® eShunt® System in Normal Pressure Hydrocephalus [NA]
A US pilot study of the CereVasc eShunt System for normal pressure hydrocephalus is active but not recruiting.
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CLINICAL_TRIALS research · 2025-05-11Clinical Trial Update: Addressing Health Disparities in Normal Pressure Hydrocephalus (NPH) in Maryland [NA]
A clinical trial update from Johns Hopkins exploring health disparities in Normal Pressure Hydrocephalus in Maryland; the study is not yet r…
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CLINICAL_TRIALS trial_result · 2025-04-06Clinical Trial Update: A Pilot Biomarker Study Assessing Alpha-synuclein Aggregates Across Biofluid Reservoirs in Patients With Synucleinopathies
A terminated pilot biomarker study evaluating alpha-synuclein aggregates across biofluid reservoirs in synucleinopathies.
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CLINICAL_TRIALS research · 2025-02-21Clinical Trial Update: Role of Brain Specific Biomarkers in Hydrocephalus
A completed clinical trial update examining brain-specific biomarkers in normal pressure hydrocephalus and related brain conditions. The stu…
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CLINICAL_TRIALS trial_result · 2025-01-23Clinical Trial Update: The Usage of Telemetric Prechamber Sensor Reservoir in Management of Normal Pressure Hydrocephalus. Comparisson of Benefit for Patients with Implanted Telemetric Prechamber Sensor Reservoir.
A completed clinical trial evaluates the use of a telemetric prechamber sensor reservoir to manage normal pressure hydrocephalus and compare…
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CLINICAL_TRIALS research · 2024-12-16Clinical Trial Update: Proteinopathies Expression in Skin of Neurodegenerative Disorders
Clinical trial examining skin expression of proteinopathies in several neurodegenerative diseases; currently recruiting and led by Universid…
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CLINICAL_TRIALS research · 2024-12-11Clinical Trial Update: European Study of Prodromal iNPH
A European study assessing prodromal idiopathic normal pressure hydrocephalus (iNPH) is currently recruiting.
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CLINICAL_TRIALS research · 2024-12-09Clinical Trial Update: Identifying Gait Changes From a CSF Tap Test Using a Smart Insole in iNPH
A recruiting clinical trial from Yonsei University is evaluating gait changes in idiopathic Normal Pressure Hydrocephalus using a CSF tap te…
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CLINICAL_TRIALS research · 2024-08-21Clinical Trial Update: The Safety and Efficacy of Rapamycin on Communicating Hydrocephalus Secondary to Intraventricular Hemorrhage [Phase 2]
A Phase 2 clinical trial is evaluating the safety and efficacy of rapamycin for treating communicating hydrocephalus caused by intraventricu…
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CLINICAL_TRIALS trial_result · 2021-01-12Clinical Trial Update: Factors Predicting Response to Shunting in Normal Pressure Hydrocephalus [NA]
A terminated clinical trial investigating factors predicting response to shunting in normal pressure hydrocephalus; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2018-12-19Clinical Trial Update: Acetazolamide for Treating NPH in Shunt-candidates Patients [Phase 2]
Phase 2 clinical trial evaluating acetazolamide for treating normal pressure hydrocephalus in shunt-candidate patients.
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CLINICAL_TRIALS trial_result · 2018-11-02Clinical Trial Update: A Randomized Cross-over Study for Normal Pressure Hydrocephalus [NA]
A completed randomized cross-over clinical trial evaluating treatment for normal pressure hydrocephalus; results posted in 2018.
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CLINICAL_TRIALS trial_result · 2017-04-13Clinical Trial Update: Normal Pressure Hydrocephalus Treatment by Acetazolamide [Phase 3]
Phase 3 trial of acetazolamide for normal pressure hydrocephalus was terminated.
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CLINICAL_TRIALS trial_result · 2017-04-04Clinical Trial Update: Prognostic Value of Transforming Growth Factor-Beta 1 in Normal Pressure Hydrocephalus
This update summarizes the completed clinical trial assessing the prognostic value of Transforming Growth Factor-Beta 1 in normal pressure h…