Nonalcoholic Steatohepatitis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2022-06-14Clinical Trial Update: LIFT Study: A Safety, Tolerability, Efficacy, and Pharmacokinetics Study of TERN-101 in Subjects With Non-Cirrhotic Non-Alcoholic Steatohepatitis (NASH) [Phase 2]
Phase 2 study assessing safety, tolerability, efficacy, and pharmacokinetics of TERN-101 in non-cirrhotic non-alcoholic steatohepatitis (NAS…
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CLINICAL_TRIALS trial_result · 2022-04-25Clinical Trial Update: Clinical Trial to Investigate the Anti-oxidant Activity of Heptex in Patients With Apparent Risk Factors of NASH [Phase 2]
Phase 2 trial investigating the antioxidant activity of Heptex in patients with nonalcoholic steatohepatitis has completed.
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CLINICAL_TRIALS trial_result · 2022-03-18Clinical Trial Update: Effect of Oral Anti-diabetic Medication on Liver Fat in Subjects With Type II Diabetes and Non-alcoholic Fatty Liver [Phase 4]
Phase 4 clinical trial examining the impact of an oral anti-diabetic medication on liver fat in adults with type 2 diabetes and non-alcoholi…
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CLINICAL_TRIALS trial_result · 2022-03-16Clinical Trial Update: The Leukotriene Receptor Antagonist Montelukast in the Treatment of Non-alcoholic Steatohepatitis [Phase 1, Phase 2]
Clinical trial updates Montelukast for non-alcoholic steatohepatitis in Phase 1/2; the study is completed.
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CLINICAL_TRIALS trial_result · 2022-03-10Clinical Trial Update: AURORA: A Study for the Efficacy and Safety of Cenicriviroc (CVC) for the Treatment of Liver Fibrosis in Adults With Nonalcoholic Steatohepatitis (NASH) [Phase 3]
Phase 3 trial for cenicriviroc (CVC) in adults with nonalcoholic steatohepatitis was terminated; results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-02-02Clinical Trial Update: Safety, Tolerability, and Efficacy of Selonsertib, Firsocostat, and Cilofexor in Adults With Nonalcoholic Steatohepatitis (NASH) [Phase 2]
Phase 2 trial assessing safety, tolerability, and efficacy of selonsertib, firsocostat, and cilofexor in adults with nonalcoholic steatohepa…
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CLINICAL_TRIALS trial_result · 2022-02-02Clinical Trial Update: Rollover Study of Cenicriviroc for the Treatment of Liver Fibrosis in Participants With Nonalcoholic Steatohepatitis [Phase 2]
Phase 2 rollover study of cenicriviroc for liver fibrosis in nonalcoholic steatohepatitis was terminated; results posted in 2022.
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CLINICAL_TRIALS trial_result · 2021-12-29Clinical Trial Update: A Study of HTD1801 in Adults With Nonalcoholic Steatohepatitis (NASH) and Type 2 Diabetes Mellitus (T2DM) [Phase 2]
Phase 2 study of HTD1801 in adults with nonalcoholic steatohepatitis (NASH) and type 2 diabetes mellitus (T2DM) completed; results posted in…
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CLINICAL_TRIALS trial_result · 2021-11-16Clinical Trial Update: Efficacy and Safety of Elobixibat in Combination With Cholestyramine for Nonalcoholic Fatty Liver Disease [Phase 2]
Phase 2 trial assessing the efficacy and safety of elobixibat in combination with cholestyramine for nonalcoholic fatty liver disease and no…
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CLINICAL_TRIALS trial_result · 2021-07-27Clinical Trial Update: Comparing the Effects of Vitamin E, Ursodeoxycholic Acid and Pentoxyfylline on Egyptian Non-alcoholic Steatohepatitis (NASH) Patients [Phase 4]
Phase 4 trial comparing vitamin E, ursodeoxycholic acid, and pentoxifylline in Egyptian patients with nonalcoholic steatohepatitis (NASH) ha…
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CLINICAL_TRIALS trial_result · 2021-07-15Clinical Trial Update: The HepQuant SHUNT Test for Monitoring Liver Disease and Treatment Effects by Measuring Liver Function and Physiology [Phase 2]
Phase 2 clinical trial update for the HepQuant SHUNT test in monitoring liver disease (NASH) and treatment effects; study terminated with re…
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CLINICAL_TRIALS trial_result · 2021-07-15Clinical Trial Update: Safety, Tolerability, and Efficacy of Monotherapy and Combination Regimens in Participants With Nonalcoholic Steatohepatitis (NASH) [Phase 2]
Phase 2 trial evaluating monotherapy and combination regimens for nonalcoholic steatohepatitis (NASH) completed; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-07-12Clinical Trial Update: A Study of MSDC-0602K to Assess Glycemic Control and Cardiovascular Outcomes in Patients With Pre-T2D or T2D and NAFLD/NASH [Phase 3]
Phase 3 study update evaluating MSDC-0602K for glycemic control and cardiovascular outcomes in pre-diabetes/Type 2 diabetes with NAFLD/NASH;…
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CLINICAL_TRIALS trial_result · 2021-06-14Clinical Trial Update: Biomarkers of Liver Pathology in Patients With Presumed Non-Alcoholic Steatohepatitis Following Bariatric Surgery [NA]
Clinical trial update studying biomarkers of liver pathology in patients with presumed non-alcoholic steatohepatitis after bariatric surgery…
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CLINICAL_TRIALS trial_result · 2021-06-01Clinical Trial Update: Study to Evaluate MET409 Alone or in Combination With Empagliflozin in Patients With Type 2 Diabetes and NASH [Phase 2]
Phase 2 trial evaluating MET409 alone or with empagliflozin in patients with type 2 diabetes and nonalcoholic steatohepatitis (NASH).
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CLINICAL_TRIALS trial_result · 2021-02-03Clinical Trial Update: Safety and Tolerability of Novel Medical Nutrition Products for NAFLD Treatment [Phase 2, Phase 3]
Phase 2/3 clinical trial update assessing safety and tolerability of novel medical nutrition products for NAFLD/NASH treatment.
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CLINICAL_TRIALS trial_result · 2020-12-17Clinical Trial Update: Study to Evaluate the Pharmacokinetics of Firsocostat or Fenofibrate in Adults With Normal and Impaired Hepatic Function [Phase 1]
Phase 1 pharmacokinetics study evaluating firsocostat or fenofibrate in adults with normal and impaired hepatic function; completed with res…
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CLINICAL_TRIALS trial_result · 2020-12-03Clinical Trial Update: Study to Evaluate the Safety and Efficacy of Selonsertib, Firsocostat, Cilofexor, and Combinations in Participants With Bridging Fibrosis or Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (NASH) [Phase 2]
Phase 2 trial evaluating multiple drugs (Selonsertib, Firsocostat, Cilofexor, and combinations) for bridging fibrosis or compensated cirrhos…
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CLINICAL_TRIALS trial_result · 2020-11-24Clinical Trial Update: CLINICAL PROTOCOL to Investigate the Long-term Safety and Efficacy of Metreleptin in Various Forms of Partial Lipodystrophy [Phase 2]
Phase 2 clinical protocol update assessing long-term safety and efficacy of metreleptin in various forms of partial lipodystrophy; study sta…
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CLINICAL_TRIALS trial_result · 2020-10-14Clinical Trial Update: Safety and Tolerability of HepaStem in Patients With Cirrhotic and Pre-cirrhotic NASH Patients [Phase 1, Phase 2]
Clinical trial updates on HepaStem show safety and tolerability in patients with cirrhotic and pre-cirrhotic nonalcoholic steatohepatitis (N…
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CLINICAL_TRIALS trial_result · 2020-10-12Clinical Trial Update: Study in Healthy Volunteers to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GS-9674 (Cilofexor), and the Effect of Food on GS-9674 Pharmacokinetics and Pharmacodynamics [Phase 1]
Phase 1 study evaluating safety, tolerability, PK/PD of GS-9674 (cilofexor) and effect of food on PK/PD in healthy volunteers; completed wit…
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CLINICAL_TRIALS trial_result · 2020-09-30Clinical Trial Update: Pharmacokinetics and Pharmacodynamics of Cilofexor in Adults With Normal and Impaired Hepatic Function [Phase 1]
Phase 1 study reporting pharmacokinetics and pharmacodynamics of cilofexor in adults with normal and impaired hepatic function; completed wi…
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CLINICAL_TRIALS trial_result · 2020-09-28Clinical Trial Update: Clinical Trial to Evaluate Efficacy of GR-MD-02 for Treatment of Liver Fibrosis in Patients With NASH With Advanced Fibrosis [Phase 2]
Phase 2 trial evaluating GR-MD-02 for liver fibrosis in NASH with advanced fibrosis has completed successfully and posted results.
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CLINICAL_TRIALS trial_result · 2020-09-04Clinical Trial Update: Rifaximin in Fatty Liver Disease [Phase 4]
Phase 4 trial of rifaximin for fatty liver disease was terminated; results posted but status terminated.
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CLINICAL_TRIALS trial_result · 2020-09-04Clinical Trial Update: Companion Protocol for Methacetin Breath Test (MBT) in Conatus Protocol IDN-6556-14
A completed clinical trial update for a companion protocol related to the Methacetin Breath Test in the Conatus protocol; results posted in …