Nonalcoholic Steatohepatitis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-08-17Clinical Trial Update: Study of Gemcabene in Adults With FPLD [Phase 1, Phase 2]
Phase 1/2 trial updates for gemcabene in adults with familial partial lipodystrophy (FPLD) and hypertriglyceridemia have been completed with…
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CLINICAL_TRIALS trial_result · 2020-07-24Clinical Trial Update: Study to Evaluate Safety, Tolerability, and Efficacy of GS-0976 in Adults With Nonalcoholic Steatohepatitis [Phase 2]
Phase 2 trial update for GS-0976 in adults with nonalcoholic steatohepatitis (NASH) completed with results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-07-23Clinical Trial Update: The Efficacy and Safety of Pioglitazone in Patients With Nonalcoholic Steatohepatitis [Phase 2]
Phase 2 clinical trial evaluating the efficacy and safety of pioglitazone in patients with nonalcoholic steatohepatitis (NASH).
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CLINICAL_TRIALS trial_result · 2020-07-21Clinical Trial Update: Colesevelam Versus Placebo in the Treatment of Nonalcoholic Steatohepatitis [Phase 2]
A Phase 2 trial comparing colesevelam to placebo in nonalcoholic steatohepatitis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-06-29Clinical Trial Update: Safety and Efficacy of Selonsertib in Adults With Nonalcoholic Steatohepatitis (NASH) and Bridging (F3) Fibrosis [Phase 3]
Phase 3 trial of Selonsertib for nonalcoholic steatohepatitis (NASH) with bridging fibrosis (F3) was terminated; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-05-07Clinical Trial Update: Safety and Efficacy of Selonsertib in Adults With Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (NASH) [Phase 3]
Phase 3 trial evaluating safety and efficacy of selonsertib in adults with compensated cirrhosis due to nonalcoholic steatohepatitis (NASH) …
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CLINICAL_TRIALS trial_result · 2020-03-10Clinical Trial Update: Phase 2a, Dose-ranging Study With PF-05221304 in Nonalcoholic Fatty Liver Disease (NAFLD) [Phase 2]
Phase 2a dose-ranging study of PF-05221304 in nonalcoholic fatty liver disease/nonalcoholic steatohepatitis completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-01-13Clinical Trial Update: Tesamorelin Effects on Liver Fat and Histology in HIV [NA]
Clinical trial update reporting on tesamorelin effects on liver fat and histology in HIV patients with NAFLD/NASH; study completed with resu…
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CLINICAL_TRIALS trial_result · 2019-11-22Clinical Trial Update: Palliative Care for Non-Malignant Diseases (COMPASS Trial) [NA]
Clinical trial update for the COMPASS trial on palliative care in non-malignant liver diseases, terminated with posted results in 2019.
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CLINICAL_TRIALS trial_result · 2019-06-25Clinical Trial Update: Researching an Effect of GLP-1 Agonist on Liver STeatosis (REALIST) [Phase 4]
A Phase 4 trial investigating the effect of a GLP-1 agonist on liver steatosis in adults with type 2 diabetes and nonalcoholic steatohepatit…
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CLINICAL_TRIALS trial_result · 2019-05-10Clinical Trial Update: Efficacy and Safety Study of Cenicriviroc for the Treatment of Nonalcoholic Steatohepatitis (NASH) in Adult Participants With Liver Fibrosis [Phase 2]
Phase 2 trial assessing cenicriviroc for nonalcoholic steatohepatitis with liver fibrosis completed; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-01-29Clinical Trial Update: Evaluating the Safety, Tolerability, and Efficacy of GS-9674 in Participants With Nonalcoholic Steatohepatitis (NASH) [Phase 2]
Phase 2 trial evaluating the safety, tolerability, and efficacy of cilofexor (GS-9674) in nonalcoholic steatohepatitis has completed with re…
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CLINICAL_TRIALS trial_result · 2019-01-07Clinical Trial Update: JKB-121 for the Treatment of Nonalcoholic Steatohepatitis [Phase 2]
Phase 2 clinical trial update for JKB-121 in nonalcoholic steatohepatitis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-09-11Clinical Trial Update: Prevalence of Non-alcoholic Fatty Liver Disease (NAFLD) in Hispanics With Diabetes Mellitus Type 2 (T2DM) and Role of Treatment [Phase 4]
Phase 4 clinical trial update on prevalence of NAFLD/Nonalcoholic Steatohepatitis in Hispanics with type 2 diabetes and the role of treatmen…
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CLINICAL_TRIALS trial_result · 2018-07-17Clinical Trial Update: Hydroxytyrosol and Vitamin E in Pediatric NASH [Phase 3]
Phase 3 pediatric trial assessing hydroxytyrosol and vitamin E for nonalcoholic fatty liver disease (NAFLD) / nonalcoholic steatohepatitis (…
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CLINICAL_TRIALS trial_result · 2018-06-04Clinical Trial Update: Combination Obeticholic Acid (OCA) and Statins for Monitoring of Lipids (CONTROL) [Phase 2]
A Phase 2 trial update (CONTROL) investigates the combination of obeticholic acid and statins for lipid monitoring in patients with nonalcoh…
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CLINICAL_TRIALS research · 2018-03-22Clinical Trial Update: Omega-3 vs Very Low Calorie Diet for Liver Size Reduction [NA]
Clinical trial comparing Omega-3 fatty acids to a very low calorie diet for reducing liver size in obesity and NAFLD/NASH.
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CLINICAL_TRIALS trial_result · 2017-11-06Clinical Trial Update: Drug-drug Interaction Study Between EDP-305, Intraconazole and Rifampin in Healthy Volunteers [Phase 1]
A Phase 1 study evaluated potential drug-drug interactions between EDP-305 and the antifungals itraconazole and rifampin in healthy voluntee…
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CLINICAL_TRIALS trial_result · 2017-11-06Clinical Trial Update: A Study of EDP-305 in Subjects With Mild and Moderate Hepatic Impairment Compared With Normal Healthy Volunteers [Phase 1]
Phase 1 study assessing EDP-305 in subjects with mild to moderate hepatic impairment versus healthy volunteers in the context of nonalcoholi…
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CLINICAL_TRIALS research · 2017-11-01Clinical Trial Update: Fecal Microbiota Transplantation (FMT) in Nonalcoholic Steatohepatitis(NASH). A Pilot Study [Phase 1]
Phase 1 pilot study evaluating fecal microbiota transplantation for nonalcoholic fatty liver disease with suspected nonalcoholic steatohepat…
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CLINICAL_TRIALS trial_result · 2017-10-10Clinical Trial Update: Effect of Dietary and Life Style Modification on Post Liver Transplant Obesity [NA]
A trial evaluating dietary and lifestyle modifications to address obesity after liver transplantation was terminated.
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CLINICAL_TRIALS trial_result · 2017-06-14Clinical Trial Update: Clinical Protocol to Investigate the Efficacy of Recombinant Human Leptin (Metreleptin) in Nonalcoholic Steatohepatitis (NASH) or Nonalcoholic Fatty Liver Disease (NAFLD) Associated With Lipodystrophy [Phase 2]
A Phase 2 clinical trial evaluating metreleptin for nonalcoholic fatty liver disease and nonalcoholic steatohepatitis associated with lipody…
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CLINICAL_TRIALS trial_result · 2017-05-30Clinical Trial Update: The Role of Leptin Receptors in NASH
This clinical trial evaluated the role of leptin receptors in nonalcoholic steatohepatitis (NASH) and metabolic syndrome; the study has comp…
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CLINICAL_TRIALS trial_result · 2017-05-24Clinical Trial Update: A Study of BMS-986171 in Healthy People to Assess Safety, to Measure Blood Levels of Drug, and to Find Out What the Drug Does to the Body [Phase 1]
Phase 1 study of BMS-986171 in healthy volunteers to assess safety, pharmacokinetics, and pharmacodynamics; the trial has completed.
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CLINICAL_TRIALS trial_result · 2017-05-16Clinical Trial Update: Nutritional Counseling vs. Nutritional Supplements for NASH - a Randomized Prospective, Open Label Pilot Study [Phase 2]
Phase 2 randomized pilot comparing nutritional counseling to nutritional supplements for nonalcoholic fatty liver disease and nonalcoholic s…