Nonalcoholic Steatohepatitis
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CLINICAL_TRIALS trial_result · 2025-04-18Clinical Trial Update: Ph 2 Study of the Safety and Efficacy of Three HU6 Dose Levels and Placebo in Nonalcoholic Steatohepatitis [Phase 2]
Clinical trial update for a Phase 2 study evaluating three HU6 dose levels versus placebo in nonalcoholic steatohepatitis; the trial status …
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CLINICAL_TRIALS trial_result · 2025-04-16Clinical Trial Update: LITMUS Imaging Study
Clinical trial update on the LITMUS Imaging Study evaluating nonalcoholic fatty liver disease and nonalcoholic steatohepatitis. The study st…
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CLINICAL_TRIALS research · 2025-04-11Clinical Trial Update: To Evaluate the Safety, Tolerability, Pharmacokinetics and Food Effects of IMM-H014 in Healthy Subjects [Phase 1]
Phase 1 clinical trial update evaluating safety, tolerability, pharmacokinetics, and food effects of IMM-H014 in healthy subjects, with a fo…
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CLINICAL_TRIALS research · 2025-04-09Clinical Trial Update: A Study of Efruxifermin in Subjects With Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (NASH) (Symmetry) [Phase 2]
A Phase 2 clinical trial update for efruxifermin in adults with nonalcoholic steatohepatitis and compensated cirrhosis shows the study is ac…
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CLINICAL_TRIALS research · 2025-04-08Clinical Trial Update: The Ameliorative Effect of C-Kit (+) Hepatic Endothelial Cells With Mertk Deficiency on Nonalcoholic Steatohepatitis
A clinical trial update on a cell-based therapy using C-Kit positive hepatic endothelial cells with MerTK deficiency for nonalcoholic fatty …
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: Low-Dose Pioglitazone in Patients With NASH (AIM 2) [Phase 2]
This clinical trial update reports a Phase 2 study of low-dose pioglitazone for nonalcoholic steatohepatitis in patients with type 2 diabete…
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CLINICAL_TRIALS trial_result · 2025-03-26Clinical Trial Update: Study of Aldafermin (NGM282) in Subjects With Compensated Cirrhosis (ALPINE 4) [Phase 2]
ALPINE 4, a Phase 2 study of Aldafermin (NGM282) in subjects with compensated cirrhosis and nonalcoholic steatohepatitis, has completed with…
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CLINICAL_TRIALS trial_result · 2025-03-26Clinical Trial Update: Spironolactone Therapy In Young Women With NASH [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating spironolactone for nonalcoholic steatohepatitis in young women has completed and posted its results.
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CLINICAL_TRIALS research · 2025-03-24Clinical Trial Update: Longitudinal Observational Study Of Chinese With NAFLD/NASH
A longitudinal observational study enrolling Chinese participants with nonalcoholic fatty liver disease or nonalcoholic steatohepatitis is c…
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CLINICAL_TRIALS research · 2025-03-24Clinical Trial Update: Nonalcoholic Steatohepatitis in Chinese Children
A clinical trial registry entry updates the status to recruiting for a study on non-alcoholic fatty liver disease and nonalcoholic steatohep…
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CLINICAL_TRIALS research · 2025-03-21Clinical Trial Update: Effect of Erugliflozin On Liver Fat, Liver Fibrosis and Glycemic Control in Type II DM Patients With NASH/NAFLD [Phase 4]
Phase 4 clinical trial investigating the effect of erugliflozin on liver fat, liver fibrosis, and glycemic control in patients with type 2 d…
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CLINICAL_TRIALS research · 2025-03-21Clinical Trial Update: Optimizing Noninvasive assessMent Of DysmEtabolic Compensated Advanced Liver Disease [NA]
This ClinicalTrials.gov entry describes a study aimed at optimizing noninvasive assessment of dysmetabolic compensated advanced liver diseas…
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CLINICAL_TRIALS research · 2025-03-19Clinical Trial Update: A Randomized, Double-blind, Placebo-controlled Study of ZSP1601 in Adult Subjects With Nonalcoholic Steatohepatitis (NASH) [Phase 2]
A Phase 2 randomized, double-blind, placebo-controlled trial of ZSP1601 in adults with Nonalcoholic Steatohepatitis (NASH); the study is cur…
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CLINICAL_TRIALS research · 2025-03-18Clinical Trial Update: Quantitative Ultrasound Techniques for Diagnosis of Nonalcoholic Steatohepatitis
This clinical trial update notes ongoing recruitment for a study evaluating quantitative ultrasound methods to diagnose nonalcoholic steatoh…
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CLINICAL_TRIALS research · 2025-03-17Clinical Trial Update: Secondary and Tertiary Digital Prevention of Non-alcoholic and Dysmetabolic Liver Disease
This clinical trial update describes a study on digital prevention strategies for nonalcoholic fatty liver disease and nonalcoholic steatohe…
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CLINICAL_TRIALS trial_result · 2025-03-12Clinical Trial Update: DUET Study: A Clinical Study to Evaluate the Safety, Efficacy, Pharmacokinetics and Pharmacodynamics of Orally Administered TERN-501 as Monotherapy and in Combination With TERN-101 in Noncirrhotic Adults With Presumed Non-Alcoholic Steatohepatitis [Phase 2]
Phase 2 DUET study evaluating the safety, efficacy, pharmacokinetics and pharmacodynamics of orally administered TERN-501 as monotherapy and…
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CLINICAL_TRIALS research · 2025-03-06Clinical Trial Update: MAFLD Fibrosis Score for Detecting Fibrotic NASH in MAFLD Egyptian Patients
This completed clinical trial evaluated the MAFLD fibrosis score's ability to detect fibrotic NASH in Egyptian patients with metabolic-assoc…
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CLINICAL_TRIALS trial_result · 2025-02-28Clinical Trial Update: A Phase 2b Study of Icosabutate in Fatty Liver Disease [Phase 2]
A Phase 2b trial of Icosabutate for nonalcoholic steatohepatitis (NASH) has completed, and results have been posted.
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CLINICAL_TRIALS trial_result · 2025-02-17Clinical Trial Update: Phase 1 Study to Evaluate the Safety and Tolerability of VK2735 [Phase 1]
A Phase 1 study to evaluate the safety and tolerability of VK2735 in obesity/weight management and nonalcoholic steatohepatitis has complete…
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CLINICAL_TRIALS trial_result · 2025-02-17Clinical Trial Update: ALG-055009 in Non-cirrhotic Adults With MASH (HERALD) [Phase 2]
Phase 2 trial update: ALG-055009 in non-cirrhotic adults with metabolic dysfunction-associated steatohepatitis/nonalcoholic steatohepatitis …
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CLINICAL_TRIALS trial_result · 2025-02-14Clinical Trial Update: Conditionally Increased Output (CIO) Enhanced Ultrasound System [NA]
The clinical trial update reports the completion of the CIO Enhanced Ultrasound System study conducted at Massachusetts General Hospital, in…
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CLINICAL_TRIALS trial_result · 2025-01-24Clinical Trial Update: A Study of Tirzepatide (LY3298176) in Participants With Nonalcoholic Steatohepatitis (NASH) [Phase 2]
A Phase 2 study of tirzepatide in nonalcoholic steatohepatitis has completed with results posted.
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CLINICAL_TRIALS research · 2025-01-08Clinical Trial Update: Study to Evaluate the Safety, Tolerability, and Efficacy of ASC41 Tablets in Adult Patients With NASH [Phase 2]
A Phase 2 trial is evaluating ASC41 tablets for safety, tolerability, and efficacy in adults with nonalcoholic fatty liver disease and nonal…
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CLINICAL_TRIALS trial_result · 2024-12-24Clinical Trial Update: Safety Evaluation of IV Tc 99m Tilmanocept and Comparison of Imaging With Sulfur Colloid in Subjects With and Without NASH [Phase 1]
Phase 1 safety evaluation of intravenous Tc-99m tilmanocept and imaging with sulfur colloid in subjects with and without nonalcoholic steato…
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CLINICAL_TRIALS trial_result · 2024-12-19Clinical Trial Update: De Novo Lipogenesis in Severity of NAFLD
A completed clinical trial from the University of Missouri-Columbia investigates the role of de novo lipogenesis in the severity of nonalcoh…