Nonalcoholic Steatohepatitis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: To Test Whether Time-restricted Eating Coupled With a Healthy Diet is Beneficial in Liver Cancer Patients [NA]
This ClinicalTrials.gov update indicates a study evaluating whether time-restricted eating plus a healthy diet benefits adults with liver ca…
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CLINICAL_TRIALS research · 2025-08-03Clinical Trial Update: Estrogen Administration for the Treatment of NASH in Postmenopausal Women [Phase 3]
A Phase 3 clinical trial is investigating estrogen administration as a treatment for nonalcoholic steatohepatitis (NASH) in postmenopausal w…
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: Biometabolic Outcomes After Weight Loss Surgery: An Individualized Approach [NA]
Clinical trial update from University of Missouri-Columbia describing an individualized approach to assessing metabolic outcomes after weigh…
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: Biomarkers of Steatohepatitis in Type 2 Diabetes Patients
This clinical trial update describes a study on biomarkers of steatohepatitis in patients with type 2 diabetes, which is currently not yet r…
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CLINICAL_TRIALS trial_result · 2025-08-01Clinical Trial Update: A Safety, Tolerability, Pharmacokinetics/Pharmacodynamics Study of HEC169584 Capsules in Healthy Subjects [Phase 1]
Phase 1 safety, tolerability, and pharmacokinetics/pharmacodynamics study of HEC169584 capsules in healthy subjects. The trial lists Nonalco…
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CLINICAL_TRIALS trial_result · 2025-07-31Clinical Trial Update: A Trial to Learn if Receiving ALN-PNP siRNA is Safe and Well Tolerated, and How it Works in Adult Participants With Nonalcoholic Fatty Liver Disease (NAFLD) and a Genetic Risk Factor [Phase 1]
Phase 1 clinical trial update assessing safety, tolerability, and mechanism of ALN-PNP siRNA in adults with nonalcoholic fatty liver disease…
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: Bariatric Embolization of Arteries for the Treatment of Nonalcoholic Steatohepatitis [NA]
This clinical trial update describes NCT02933554, evaluating bariatric embolization of arteries as a treatment for nonalcoholic steatohepati…
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CLINICAL_TRIALS withdrawal · 2025-07-25Clinical Trial Update: Digital Therapeutic Lifestyle Intervention Program for Patients With MASLD [NA]
A clinical trial evaluating a digital therapeutic lifestyle intervention for metabolic dysfunction-associated steatotic liver disease (MASLD…
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CLINICAL_TRIALS trial_result · 2025-07-20Clinical Trial Update: Knockdown of HSD17B13 mRNA, Pharmacokinetics, Safety, and Tolerability, of AZD7503 in Non-Alcoholic Fatty Liver Disease [Phase 1]
Phase 1 trial evaluating AZD7503 for HSD17B13 mRNA knockdown with pharmacokinetics, safety, and tolerability data in non-alcoholic fatty liv…
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CLINICAL_TRIALS trial_result · 2025-07-20Clinical Trial Update: A Study to Investigate Safety, Tolerability, and Pharmacokinetics of AZD7503 in Participants With Suspected NASH. [Phase 1]
A Phase 1 study evaluating safety, tolerability, and pharmacokinetics of AZD7503 in participants with suspected nonalcoholic steatohepatitis…
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CLINICAL_TRIALS trial_result · 2025-07-09Clinical Trial Update: A Study in Participants With Non-cirrhotic NASH With Fibrosis [Phase 2]
This Phase 2 trial update from AstraZeneca reports results for non-cirrhotic non-alcoholic steatohepatitis with fibrosis, with results poste…
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CLINICAL_TRIALS research · 2025-07-09Clinical Trial Update: Prospective Cohort and Biobank of Patients With Nonalcoholic Fatty Liver Disease
A prospective cohort and biobank study on nonalcoholic fatty liver disease and related steatohepatitis (NAFLD/MASH/NASH) is currently recrui…
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CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: Evaluation of Efficacy, Safety and Tolerability of Aldafermin in a Phase 2b, Randomized, Double-blind, Placebo-controlled, Multi-center Study In Subjects With Nonalcoholic Steatohepatitis and Stage 2/3 Fibrosis (ALPINE 2/3) [Phase 2]
The Phase 2b ALPINE 2/3 trial evaluating aldafermin in adults with nonalcoholic steatohepatitis and stage 2/3 fibrosis has completed, and re…
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CLINICAL_TRIALS trial_result · 2025-06-26Clinical Trial Update: Study of NGM282 in Patients With Nonalcoholic Steatohepatitis (NASH) [Phase 2]
Phase 2 study of NGM282 (Aldafermin) in patients with nonalcoholic steatohepatitis (NASH) has completed and results have been posted.
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: Accuracy of Imaging Techniques in Diagnosing Steatohepatitis and Fibrosis in NAFLD Patients [NA]
A recruiting trial evaluating the accuracy of imaging techniques for diagnosing non-alcoholic steatohepatitis and fibrosis in patients with …
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CLINICAL_TRIALS trial_result · 2025-06-25Clinical Trial Update: Safety Study of OA-235i in Subjects With Nonalcoholic Steatohepatitis [Phase 1]
A Phase 1 safety study of OA-235i in nonalcoholic steatohepatitis and nonalcoholic fatty liver disease has completed.
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CLINICAL_TRIALS trial_result · 2025-06-24Clinical Trial Update: ALT-801 (Pemvidutide) in Healthy Overweight and Obese Volunteers to Study Safety and Tolerability [Phase 1]
Phase 1 trial of Pemvidutide (ALT-801) in healthy overweight and obese volunteers to assess safety and tolerability has been completed. The …
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CLINICAL_TRIALS trial_result · 2025-06-24Clinical Trial Update: Pemvidutide (ALT-801) DDI Study in Healthy Volunteers [Phase 1]
Phase 1 drug-drug interaction study of Pemvidutide (ALT-801) in healthy volunteers has completed.
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CLINICAL_TRIALS research · 2025-06-15Clinical Trial Update: Vertical Sleeve Gastrectomy and Lifestyle Modification for the Treatment of Non-Alcoholic Steatohepatitis [NA]
A clinical trial update indicates recruitment for a study evaluating vertical sleeve gastrectomy plus lifestyle modification for Nonalcoholi…
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: A Phase 3 Study to Evaluate the Effect of Resmetirom on Clinical Outcomes in Patients With Well-compensated NASH Cirrhosis (MAESTRO-NASH-OUTCOMES) [Phase 3]
This is a Phase 3 clinical trial update indicating the MAESTRO-NASH-OUTCOMES study of resmetirom in patients with well-compensated NASH cirr…
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CLINICAL_TRIALS trial_result · 2025-05-30Clinical Trial Update: HTD1801 in Adults With Nonalcoholic Steatohepatitis and Liver Fibrosis Who Have Type 2 Diabetes or Pre-Diabetes [Phase 2]
A completed Phase 2 clinical trial evaluating HTD1801 in adults with nonalcoholic steatohepatitis and liver fibrosis who have type 2 diabete…
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: The COherence of Scatter Identification and Exclusion Algorithm Study
A clinical trial update for the COherence of Scatter Identification and Exclusion Algorithm Study, sponsored by the Institute of Cancer Rese…
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CLINICAL_TRIALS withdrawal · 2025-05-15Clinical Trial Update: A Phase 3 Study Evaluating the Safety and Efficacy of Denifanstat in Patients With MASH and F2/F3 Fibrosis [Phase 3]
Phase 3 study evaluating denifanstat for metabolic dysfunction-associated steatohepatitis (MASH) and fibrosis has been withdrawn.
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CLINICAL_TRIALS trial_result · 2025-05-09Clinical Trial Update: Study of TVB-2640 in Subjects With Nonalcoholic Steatohepatitis (NASH) [Phase 2]
Sagimet Biosciences completed a Phase 2 study of TVB-2640 in nonalcoholic steatohepatitis (NASH) with results posted in May 2025.
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CLINICAL_TRIALS trial_result · 2025-05-08Clinical Trial Update: A Study of Efruxifermin in Non-Cirrhotic Subjects With Histologically Confirmed Nonalcoholic Steatohepatitis (NASH) [Phase 2]
Phase 2 trial of Efruxifermin in non-cirrhotic Nonalcoholic Steatohepatitis has completed and posted results.