Nonalcoholic Steatohepatitis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-08-19Clinical Trial Update: A Study to Evaluate How Ontamalimab Works and Assess Its Safety and Tolerability in People With Nonalcoholic Steatohepatitis With Fibrosis Stages 1 to 4 [Phase 1]
A Phase 1 study evaluating ontamalimab for nonalcoholic steatohepatitis with fibrosis (stages 1-4) has been terminated and results have been…
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CLINICAL_TRIALS trial_result · 2025-08-01Clinical Trial Update: A Safety, Tolerability, Pharmacokinetics/Pharmacodynamics Study of HEC169584 Capsules in Healthy Subjects [Phase 1]
Phase 1 safety, tolerability, and pharmacokinetics/pharmacodynamics study of HEC169584 capsules in healthy subjects. The trial lists Nonalco…
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CLINICAL_TRIALS trial_result · 2025-07-31Clinical Trial Update: A Trial to Learn if Receiving ALN-PNP siRNA is Safe and Well Tolerated, and How it Works in Adult Participants With Nonalcoholic Fatty Liver Disease (NAFLD) and a Genetic Risk Factor [Phase 1]
Phase 1 clinical trial update assessing safety, tolerability, and mechanism of ALN-PNP siRNA in adults with nonalcoholic fatty liver disease…
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CLINICAL_TRIALS trial_result · 2025-07-20Clinical Trial Update: Knockdown of HSD17B13 mRNA, Pharmacokinetics, Safety, and Tolerability, of AZD7503 in Non-Alcoholic Fatty Liver Disease [Phase 1]
Phase 1 trial evaluating AZD7503 for HSD17B13 mRNA knockdown with pharmacokinetics, safety, and tolerability data in non-alcoholic fatty liv…
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CLINICAL_TRIALS trial_result · 2025-07-20Clinical Trial Update: A Study to Investigate Safety, Tolerability, and Pharmacokinetics of AZD7503 in Participants With Suspected NASH. [Phase 1]
A Phase 1 study evaluating safety, tolerability, and pharmacokinetics of AZD7503 in participants with suspected nonalcoholic steatohepatitis…
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CLINICAL_TRIALS trial_result · 2025-07-09Clinical Trial Update: A Study in Participants With Non-cirrhotic NASH With Fibrosis [Phase 2]
This Phase 2 trial update from AstraZeneca reports results for non-cirrhotic non-alcoholic steatohepatitis with fibrosis, with results poste…
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CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: Evaluation of Efficacy, Safety and Tolerability of Aldafermin in a Phase 2b, Randomized, Double-blind, Placebo-controlled, Multi-center Study In Subjects With Nonalcoholic Steatohepatitis and Stage 2/3 Fibrosis (ALPINE 2/3) [Phase 2]
The Phase 2b ALPINE 2/3 trial evaluating aldafermin in adults with nonalcoholic steatohepatitis and stage 2/3 fibrosis has completed, and re…
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CLINICAL_TRIALS trial_result · 2025-06-26Clinical Trial Update: Study of NGM282 in Patients With Nonalcoholic Steatohepatitis (NASH) [Phase 2]
Phase 2 study of NGM282 (Aldafermin) in patients with nonalcoholic steatohepatitis (NASH) has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2025-06-25Clinical Trial Update: Safety Study of OA-235i in Subjects With Nonalcoholic Steatohepatitis [Phase 1]
A Phase 1 safety study of OA-235i in nonalcoholic steatohepatitis and nonalcoholic fatty liver disease has completed.
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CLINICAL_TRIALS trial_result · 2025-06-24Clinical Trial Update: ALT-801 (Pemvidutide) in Healthy Overweight and Obese Volunteers to Study Safety and Tolerability [Phase 1]
Phase 1 trial of Pemvidutide (ALT-801) in healthy overweight and obese volunteers to assess safety and tolerability has been completed. The …
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CLINICAL_TRIALS trial_result · 2025-06-24Clinical Trial Update: Pemvidutide (ALT-801) DDI Study in Healthy Volunteers [Phase 1]
Phase 1 drug-drug interaction study of Pemvidutide (ALT-801) in healthy volunteers has completed.
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CLINICAL_TRIALS trial_result · 2025-05-30Clinical Trial Update: HTD1801 in Adults With Nonalcoholic Steatohepatitis and Liver Fibrosis Who Have Type 2 Diabetes or Pre-Diabetes [Phase 2]
A completed Phase 2 clinical trial evaluating HTD1801 in adults with nonalcoholic steatohepatitis and liver fibrosis who have type 2 diabete…
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CLINICAL_TRIALS trial_result · 2025-05-09Clinical Trial Update: Study of TVB-2640 in Subjects With Nonalcoholic Steatohepatitis (NASH) [Phase 2]
Sagimet Biosciences completed a Phase 2 study of TVB-2640 in nonalcoholic steatohepatitis (NASH) with results posted in May 2025.
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CLINICAL_TRIALS trial_result · 2025-05-08Clinical Trial Update: A Study of Efruxifermin in Non-Cirrhotic Subjects With Histologically Confirmed Nonalcoholic Steatohepatitis (NASH) [Phase 2]
Phase 2 trial of Efruxifermin in non-cirrhotic Nonalcoholic Steatohepatitis has completed and posted results.
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CLINICAL_TRIALS trial_result · 2025-04-18Clinical Trial Update: Ph 2 Study of the Safety and Efficacy of Three HU6 Dose Levels and Placebo in Nonalcoholic Steatohepatitis [Phase 2]
Clinical trial update for a Phase 2 study evaluating three HU6 dose levels versus placebo in nonalcoholic steatohepatitis; the trial status …
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CLINICAL_TRIALS trial_result · 2025-04-16Clinical Trial Update: LITMUS Imaging Study
Clinical trial update on the LITMUS Imaging Study evaluating nonalcoholic fatty liver disease and nonalcoholic steatohepatitis. The study st…
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CLINICAL_TRIALS trial_result · 2025-03-26Clinical Trial Update: Study of Aldafermin (NGM282) in Subjects With Compensated Cirrhosis (ALPINE 4) [Phase 2]
ALPINE 4, a Phase 2 study of Aldafermin (NGM282) in subjects with compensated cirrhosis and nonalcoholic steatohepatitis, has completed with…
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CLINICAL_TRIALS trial_result · 2025-03-26Clinical Trial Update: Spironolactone Therapy In Young Women With NASH [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating spironolactone for nonalcoholic steatohepatitis in young women has completed and posted its results.
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CLINICAL_TRIALS trial_result · 2025-03-12Clinical Trial Update: DUET Study: A Clinical Study to Evaluate the Safety, Efficacy, Pharmacokinetics and Pharmacodynamics of Orally Administered TERN-501 as Monotherapy and in Combination With TERN-101 in Noncirrhotic Adults With Presumed Non-Alcoholic Steatohepatitis [Phase 2]
Phase 2 DUET study evaluating the safety, efficacy, pharmacokinetics and pharmacodynamics of orally administered TERN-501 as monotherapy and…
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CLINICAL_TRIALS trial_result · 2025-02-28Clinical Trial Update: A Phase 2b Study of Icosabutate in Fatty Liver Disease [Phase 2]
A Phase 2b trial of Icosabutate for nonalcoholic steatohepatitis (NASH) has completed, and results have been posted.
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CLINICAL_TRIALS trial_result · 2025-02-17Clinical Trial Update: Phase 1 Study to Evaluate the Safety and Tolerability of VK2735 [Phase 1]
A Phase 1 study to evaluate the safety and tolerability of VK2735 in obesity/weight management and nonalcoholic steatohepatitis has complete…
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CLINICAL_TRIALS trial_result · 2025-02-17Clinical Trial Update: ALG-055009 in Non-cirrhotic Adults With MASH (HERALD) [Phase 2]
Phase 2 trial update: ALG-055009 in non-cirrhotic adults with metabolic dysfunction-associated steatohepatitis/nonalcoholic steatohepatitis …
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CLINICAL_TRIALS trial_result · 2025-02-14Clinical Trial Update: Conditionally Increased Output (CIO) Enhanced Ultrasound System [NA]
The clinical trial update reports the completion of the CIO Enhanced Ultrasound System study conducted at Massachusetts General Hospital, in…
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CLINICAL_TRIALS trial_result · 2025-01-24Clinical Trial Update: A Study of Tirzepatide (LY3298176) in Participants With Nonalcoholic Steatohepatitis (NASH) [Phase 2]
A Phase 2 study of tirzepatide in nonalcoholic steatohepatitis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2024-12-24Clinical Trial Update: Safety Evaluation of IV Tc 99m Tilmanocept and Comparison of Imaging With Sulfur Colloid in Subjects With and Without NASH [Phase 1]
Phase 1 safety evaluation of intravenous Tc-99m tilmanocept and imaging with sulfur colloid in subjects with and without nonalcoholic steato…