Nonalcoholic Fatty Liver Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-08-13Clinical Trial Update: Nonalcoholic Fatty Liver Disease (NAFLD) Database 3
Clinical trial update for the Nonalcoholic Fatty Liver Disease (NAFLD) Database 3, sponsored by Johns Hopkins Bloomberg School of Public Hea…
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CLINICAL_TRIALS trial_result · 2025-07-31Clinical Trial Update: A Trial to Learn if Receiving ALN-PNP siRNA is Safe and Well Tolerated, and How it Works in Adult Participants With Nonalcoholic Fatty Liver Disease (NAFLD) and a Genetic Risk Factor [Phase 1]
Phase 1 clinical trial update assessing safety, tolerability, and mechanism of ALN-PNP siRNA in adults with nonalcoholic fatty liver disease…
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CLINICAL_TRIALS trial_result · 2025-07-16Clinical Trial Update: Saroglitazar Magnesium 4 mg for Nonalcoholic Fatty Liver Disease (NAFLD) in People Living With HIV in the US [Phase 2]
A Phase 2 study of saroglitazar magnesium for nonalcoholic fatty liver disease in people living with HIV was terminated in the US, and resul…
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CLINICAL_TRIALS trial_result · 2025-07-15Clinical Trial Update: Alternate Dosing Study of MK-6024 in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) (MK-6024-016) [Phase 2]
Merck's Phase 2 trial MK-6024-016 evaluating alternate dosing in adults with metabolic dysfunction-associated steatotic liver disease and no…
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CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: Ultrasound Index Fat Fraction [NA]
A completed clinical trial evaluating ultrasound index fat fraction for detecting hepatic steatosis, sponsored by SuperSonic Imagine.
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CLINICAL_TRIALS trial_result · 2025-06-25Clinical Trial Update: Safety Study of OA-235i in Subjects With Nonalcoholic Steatohepatitis [Phase 1]
A Phase 1 safety study of OA-235i in nonalcoholic steatohepatitis and nonalcoholic fatty liver disease has completed.
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CLINICAL_TRIALS trial_result · 2025-05-21Clinical Trial Update: The Effects of Dihydromiricetin on MASLD [NA]
A clinical trial evaluating Dihydromiricetin for nonalcoholic fatty liver disease (MASLD) has completed, according to ClinicalTrials.gov, sp…
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CLINICAL_TRIALS trial_result · 2025-05-09Clinical Trial Update: Study of TVB-2640 in Subjects With Nonalcoholic Steatohepatitis (NASH) [Phase 2]
Sagimet Biosciences completed a Phase 2 study of TVB-2640 in nonalcoholic steatohepatitis (NASH) with results posted in May 2025.
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CLINICAL_TRIALS trial_result · 2025-04-18Clinical Trial Update: Ph 2 Study of the Safety and Efficacy of Three HU6 Dose Levels and Placebo in Nonalcoholic Steatohepatitis [Phase 2]
Clinical trial update for a Phase 2 study evaluating three HU6 dose levels versus placebo in nonalcoholic steatohepatitis; the trial status …
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CLINICAL_TRIALS trial_result · 2025-04-16Clinical Trial Update: LITMUS Imaging Study
Clinical trial update on the LITMUS Imaging Study evaluating nonalcoholic fatty liver disease and nonalcoholic steatohepatitis. The study st…
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CLINICAL_TRIALS trial_result · 2025-04-02Clinical Trial Update: Iron Reduction for the Treatment of Diabetes and Nonalcoholic Fatty Liver Disease [NA]
A completed clinical trial evaluating whether reducing iron levels could treat diabetes and nonalcoholic fatty liver disease. The study is s…
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CLINICAL_TRIALS trial_result · 2025-03-30Clinical Trial Update: Study to Estimate How Common it is to Have Genetic Variants Associated With NAFLD
A completed Janssen-sponsored study aims to estimate how common genetic variants associated with non-alcoholic fatty liver disease are in he…
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CLINICAL_TRIALS trial_result · 2025-03-26Clinical Trial Update: Medium-term Effects of a Polyphenol-rich Beverage Based on Red Grape Pomace Extract on Non-alcoholic Fatty Liver Disease, Cardiometabolic Risk Profile and Gut Microbiota in Subjects with Type 2 Diabetes [NA]
This clinical trial evaluates a polyphenol-rich beverage derived from red grape pomace for its effects on nonalcoholic fatty liver disease, …
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CLINICAL_TRIALS trial_result · 2025-03-24Clinical Trial Update: Oral Amino Acid Nutrition to Improve Glucose Excursions in PCOS [NA]
Completed clinical trial assessing an oral amino acid nutrition formulation to improve glucose excursions in Polycystic Ovary Syndrome, with…
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CLINICAL_TRIALS trial_result · 2025-03-21Clinical Trial Update: Metabolic Interventions to Resolve Non-alcoholic Steatohepatitis (NASH) With Fibrosis (MIRNA) [Phase 2]
Pfizer completed a Phase 2 trial (MIRNA) evaluating metabolic interventions for nonalcoholic steatohepatitis with liver fibrosis. Results ha…
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CLINICAL_TRIALS trial_result · 2025-02-14Clinical Trial Update: Conditionally Increased Output (CIO) Enhanced Ultrasound System [NA]
The clinical trial update reports the completion of the CIO Enhanced Ultrasound System study conducted at Massachusetts General Hospital, in…
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CLINICAL_TRIALS trial_result · 2025-02-04Clinical Trial Update: Dapagliflozin in Type 2 Diabetes Mellitus Patients (T2DM) With Nonalcoholic Fatty Liver Disease (NAFLD) [Phase 4]
A Phase 4 clinical trial evaluating the SGLT2 inhibitor dapagliflozin in adults with Type 2 Diabetes Mellitus and Nonalcoholic Fatty Liver D…
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CLINICAL_TRIALS trial_result · 2024-12-19Clinical Trial Update: De Novo Lipogenesis in Severity of NAFLD
A completed clinical trial from the University of Missouri-Columbia investigates the role of de novo lipogenesis in the severity of nonalcoh…
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CLINICAL_TRIALS trial_result · 2024-11-25Clinical Trial Update: Comparative and Additive Diagnostic Performance of Magnetic Resonance Elastography (MRE) and Corrected-T1 (cT1) for Fibrosis and Inflammation in Nonalcoholic Steatohepatitis (NASH) Using Histology As Reference
This completed clinical trial compared magnetic resonance elastography (MRE) and corrected-T1 (cT1) for diagnosing fibrosis and inflammation…
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CLINICAL_TRIALS trial_result · 2024-11-08Clinical Trial Update: Raspberry Ketone Intake Upregulates Circulating FGF21 and Induces Energy Expenditure in Humans [EARLY_Phase 1]
An early-phase trial found that raspberry ketone intake upregulates circulating FGF21 and increases energy expenditure in humans, with obesi…
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CLINICAL_TRIALS trial_result · 2024-10-24Clinical Trial Update: Saroglitazar Magnesium in Patients With Nonalcoholic Fatty Liver Disease and/or Nonalcoholic Steatohepatitis [Phase 2]
A Phase 2 trial update reports results for saroglitazar magnesium in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis. Resu…
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CLINICAL_TRIALS trial_result · 2024-10-24Clinical Trial Update: Safety, Tolerability, and Efficacy of Saroglitazar Mg 4 mg in Liver Transplant Recipients With Nonalcoholic Fatty Liver Disease (NAFLD) [Phase 2]
Phase 2 trial evaluating saroglitazar 4 mg in liver transplant recipients with nonalcoholic fatty liver disease (NAFLD) to assess safety, to…
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CLINICAL_TRIALS trial_result · 2024-10-02Clinical Trial Update: Efficacy and Safety of Pemafibrate for Nonalcoholic Fatty Liver Disease [Phase 2]
Phase 2 trial update reporting on the efficacy and safety of pemafibrate for nonalcoholic fatty liver disease.
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CLINICAL_TRIALS trial_result · 2024-09-27Clinical Trial Update: Study to Evaluate the Safety and Efficacy of ASC41 in Overweight and Obese Subjects [Phase 1]
Completed Phase 1 trial evaluating the safety and initial efficacy of ASC41 in overweight and obese subjects, including participants with NA…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Lanifibranor in Patients With Type 2 Diabetes & Nonalcoholic Fatty Liver Disease [Phase 2]
Phase 2 trial of lanifibranor in patients with nonalcoholic fatty liver disease and type 2 diabetes completed; results posted.