Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-02-12Clinical Trial Update: Pharmacokinetic Study of HS-10241 Tablets in Subjects with Hepatic Impairment and Normal Hepatic Function [Phase 1]
This Phase 1 pharmacokinetic study evaluates HS-10241 in subjects with hepatic impairment and normal hepatic function to inform dosing for a…
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CLINICAL_TRIALS trial_result · 2025-02-12Clinical Trial Update: Orlistat Overcoming Third-generation EGFR-TKI Resistance [Phase 2]
Phase 2 clinical trial evaluating whether adding orlistat can overcome resistance to osimertinib in non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2025-02-11Clinical Trial Update: Osimertinib for NSCLC With EGFR Exon 20 Insertion Mutation [Phase 2]
Phase 2 trial of osimertinib for locally advanced or metastatic non-small cell lung cancer with EGFR exon 20 insertion has completed with po…
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CLINICAL_TRIALS trial_result · 2025-02-11Clinical Trial Update: Intensified Chemo-immuno-radiotherapy With Durvalumab for Stage III Non-Small Cell Lung Cancers [Phase 2]
A Phase 2 trial of intensified chemo-immuno-radiotherapy with durvalumab for Stage III non-small cell lung cancer has completed.
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CLINICAL_TRIALS trial_result · 2025-02-11Clinical Trial Update: CSF Analysis in EGFR Mutant Non-Small Cell Lung Cancer With Leptomeningeal Disease [NA]
This entry describes a recruiting clinical trial evaluating CSF analysis in patients with EGFR-mutant non-small cell lung cancer and leptome…
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CLINICAL_TRIALS trial_result · 2025-02-10Clinical Trial Update: Pembrolizumab in Patients With Non-Small Cell Lung Cancer and a Performance Status 2 [Phase 2]
Pembrolizumab was studied in a Phase 2 trial in non-small cell lung cancer patients with performance status 2; the study has completed and r…
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CLINICAL_TRIALS trial_result · 2025-02-10Clinical Trial Update: Comparison of Efficacy and Safety of Tislelizumab (BGB-A317) Versus Docetaxel as Treatment in the Second- or Third-line Setting in Participants With Non-Small Cell Lung Cancer (NSCLC) [Phase 3]
Phase 3 trial comparing tislelizumab to docetaxel in second- or third-line non-small cell lung cancer has posted results.
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CLINICAL_TRIALS trial_result · 2025-02-10Clinical Trial Update: (Concerto) Study of BLU-451 in Advanced Cancers With EGFR Exon 20 Insertion Mutations [Phase 1]
Phase 1 study of BLU-451 for advanced cancers with EGFR Exon 20 insertion mutations has been terminated.
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CLINICAL_TRIALS trial_result · 2025-02-10Clinical Trial Update: (SYMPHONY) Phase 1/2 Study Targeting EGFR Resistance Mechanisms in NSCLC [Phase 1]
The SYMPHONY Phase 1/2 trial targeting EGFR resistance mechanisms in non-small cell lung cancer has been terminated.
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CLINICAL_TRIALS trial_result · 2025-02-10Clinical Trial Update: A Safety Study of SEA-TGT (SGN-TGT) in Advanced Cancer [Phase 1]
Seagen's SEA-TGT (SGN-TGT) Phase 1 safety study in advanced cancers has been terminated. The study enrolled patients across multiple cancer …
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CLINICAL_TRIALS trial_result · 2025-02-10Clinical Trial Update: A Study of SGN-ALPV in Advanced Solid Tumors [Phase 1]
Seagen's Phase 1 study of SGN-ALPV in advanced solid tumors has been terminated; the trial evaluated multiple cancers including ovarian, end…
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CLINICAL_TRIALS research · 2025-02-10Clinical Trial Update: Low Dose Radiotherapy Combined With Sintilimab and Chemotherapy as Neoadjuvant Therapy for Stage II-III NSCLC [Phase 2]
This clinical trial update reports a Phase 2 study evaluating low-dose radiotherapy combined with sintilimab and chemotherapy as neoadjuvant…
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CLINICAL_TRIALS trial_result · 2025-02-07Clinical Trial Update: A Study of SGN-STNV in Advanced Solid Tumors [Phase 1]
Seagen's Phase 1 study of SGN-STNV in advanced solid tumors has been terminated.
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CLINICAL_TRIALS trial_result · 2025-02-07Clinical Trial Update: Toripalimab Combined With Anlotinib and SBRT in Patients With Untreated Brain Metastases of Driven Gene-negative NSCLC [Phase 1]
Phase 1 study evaluating toripalimab with anlotinib and SBRT for untreated brain metastases in gene-negative non-small cell lung cancer has …
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CLINICAL_TRIALS trial_result · 2025-02-07Clinical Trial Update: Study of Covalent Menin Inhibitor BMF-219 in Adult Patients With KRAS Driven Non-Small Cell Lung Cancer, Pancreatic Cancer, and Colorectal Cancer [Phase 1]
A Phase 1 trial of Biomea Fusion's covalent menin inhibitor BMF-219 in KRAS-driven non-small cell lung cancer, pancreatic cancer, and colore…
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CLINICAL_TRIALS trial_result · 2025-02-07Clinical Trial Update: Remote Monitoring With Health-Coaching for Lifestyle Changes in Patients With Lung Cancer Related Fatigue [NA]
A Mayo Clinic-led study evaluating remote monitoring with health coaching for lifestyle changes to address fatigue in patients with advanced…
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CLINICAL_TRIALS research · 2025-02-07Clinical Trial Update: XNW27011 Study of Advanced Solid Tumor Subjects Who Failed Standard Therapies. [Phase 1, Phase 2]
Clinical trial update indicating an early-phase study of XNW27011 for multiple advanced solid tumors is currently recruiting.
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CLINICAL_TRIALS withdrawal · 2025-02-07Clinical Trial Update: A Study to Learn About Dacomitnib in Patients With Non-small Cell Lung Cancer Which Has Spread to the Brain.
Pfizer has withdrawn a clinical trial of dacomitnib for non-small cell lung cancer that has spread to the brain.
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CLINICAL_TRIALS research · 2025-02-07Clinical Trial Update: GT201 Injection in Combination with Teraplizumab Injection for Treatment of Patients with Non-small Cell Lung Cancer [NA]
This clinical trial update reports a study of GT201 Injection in combination with Teraplizumab Injection for non-small cell lung cancer, wit…
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CLINICAL_TRIALS trial_result · 2025-02-06Clinical Trial Update: Study of Pembrolizumab With Maintenance Olaparib or Maintenance Pemetrexed in First-line (1L) Metastatic Nonsquamous Non-Small-Cell Lung Cancer (NSCLC) (MK-7339-006, KEYLYNK-006) [Phase 3]
Phase 3 trial evaluating pembrolizumab with maintenance olaparib or maintenance pemetrexed as first-line therapy in metastatic nonsquamous n…
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CLINICAL_TRIALS research · 2025-02-06Clinical Trial Update: Effectiveness of Respiratory Muscle Training with a Mobile Application After Lobectomy [NA]
A clinical trial investigates whether respiratory muscle training delivered via a mobile app improves outcomes after lobectomy for non-small…
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CLINICAL_TRIALS research · 2025-02-06Clinical Trial Update: Retrospective Observational Study on Prediction of Response to PD-1 Immunotherapy in Patients with NSCLC
A retrospective observational study is being conducted to predict response to PD-1 immunotherapy in patients with advanced non-small cell lu…
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CLINICAL_TRIALS research · 2025-02-06Clinical Trial Update: A Study of PLB1001 in Non-small Cell Lung Cancer With c-Met Dysregulation(KUNPENG) [Phase 2]
A Phase 2 clinical trial evaluating PLB1001 in patients with non-small cell lung cancer that have c-Met dysregulation; the study status is A…
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CLINICAL_TRIALS trial_result · 2025-02-05Clinical Trial Update: Evaluation of UCPVax Plus Nivolumab as Second Line Therapy in Advanced Non Small Cell Lung Cancer [Phase 2]
Phase 2 trial evaluating UCPVax in combination with nivolumab as second-line therapy for advanced non-small cell lung cancer has completed.
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CLINICAL_TRIALS trial_result · 2025-02-05Clinical Trial Update: Liquid Biopsy to Reduce Time to Treatment for Advanced Nonsquamous NSCLC Diagnosed at Outside Sites [NA]
The trial investigates using liquid biopsy to shorten time to treatment for advanced non-small cell lung cancer diagnosed at outside sites. …