Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Lobectomy-First vs. Lymphadenectomy-First for Operable NSCLC (LOFTY) [NA]
A clinical trial called LOFTY is evaluating whether lobectomy-first or lymphadenectomy-first surgical strategies are preferable for operable…
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: A Phase 1/2 Study to Evaluate the Safety, Tolerability and PK of JIN-A02 in Patients With EGFR Mutant Advanced NSCLC [Phase 1, Phase 2]
This document describes a Phase 1/2 clinical trial evaluating the safety, tolerability, and pharmacokinetics of JIN-A02 in patients with EGF…
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: The Prospective Non-randomized Case-control Study From Real-world Lung Cancer Patients
A prospective non-randomized case-control real-world study in non-small cell lung cancer sponsored by Samsung Medical Center is currently AC…
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FDA approval · 2025-05-15FDA Approved: PACLITAXEL PROTEIN-BOUND PARTICLES FOR INJECTABLE SUSPENSION (ALBUMIN-BOUND) — Original Application (BluePoint Laboratories)
FDA approved the original application for paclitaxel protein-bound particles for injectable suspension (albumin-bound) from BluePoint Labora…
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CLINICAL_TRIALS research · 2025-05-15Clinical Trial Update: A Pilot Study of Dacomitinib With or Without Osimertinib for Patients With Metastatic EGFR Mutant Lung Cancers With Disease Progression on Osimertinib. [EARLY_Phase 1]
An early-phase pilot study evaluating dacomitinib with or without osimertinib in patients with metastatic EGFR-mutant non-small cell lung ca…
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CLINICAL_TRIALS trial_result · 2025-05-15Clinical Trial Update: Circulating Tumor DNA in Predicting Outcomes in Patients With Stage IV Head and Neck Cancer or Stage III-IV Non-small Cell Lung Cancer
A completed clinical trial evaluating whether circulating tumor DNA can predict outcomes in patients with stage IV head and neck cancer or s…
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CLINICAL_TRIALS research · 2025-05-15Clinical Trial Update: Testing the Use of Combination Immunotherapy Treatment (N-803 [ALT-803] Plus Pembrolizumab) Against the Usual Treatment for Advanced Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial) [Phase 2, Phase 3]
SWOG reports a Phase 2/3 trial evaluating N-803 (ALT-803) in combination with pembrolizumab versus standard treatment for advanced non-small…
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CLINICAL_TRIALS research · 2025-05-15Clinical Trial Update: Neoadjuvant Sacituzumab Govitecan Plus Pembrolizumab in Resectable Non-Small Cell Lung Cancer [Phase 2]
A Phase 2 neoadjuvant trial evaluating sacituzumab govitecan in combination with pembrolizumab for resectable non-small cell lung cancer is …
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CLINICAL_TRIALS research · 2025-05-15Clinical Trial Update: Clinical Study of Combined EphA2-targeted CAR-DC and CAR-T Cell Therapy for Non-small Cell Lung Cancer [Phase 1]
This Phase 1 clinical study evaluates a combined EphA2-targeted CAR-DC and CAR-T cell therapy for non-small cell lung cancer and is currentl…
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CLINICAL_TRIALS withdrawal · 2025-05-15Clinical Trial Update: Analysis of Biopsy Specimens to Study Responses to PD-1 or PD-L1 Therapies
The trial examining biopsy specimens to study responses to PD-1 or PD-L1 therapies has been withdrawn.
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CLINICAL_TRIALS research · 2025-05-15Clinical Trial Update: Avoiding Radiation Therapy Due to Intracranial Response to Chemotherapy, Targeted Therapy and/or Immuno-ONcology Therapy for Brain Metastases: Pilot Pragmatic Trial [Phase 2]
This is a Phase 2 pilot pragmatic clinical trial updating on strategies to avoid radiation therapy for brain metastases in NSCLC patients wh…
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CLINICAL_TRIALS trial_result · 2025-05-15Clinical Trial Update: Continued Access to RXDX-105 [Phase 1]
This clinical trial update concerns continued access to RXDX-105 in a Phase 1 study for non-small cell lung cancer and ovarian cancer, inclu…
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FDA approval · 2025-05-14FDA Approved: EMRELIS — Original Application (AbbVie Inc.)
FDA approved EMRELIS (telisotuzumab vedotin) under the original application submitted by AbbVie. The approval pertains to a MET-targeted ant…
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CLINICAL_TRIALS other · 2025-05-14Clinical Trial Update: RAPA-201 Therapy of Solid Tumors [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating RAPA-201 for solid tumors, including small cell and non-small cell lung cancer and several head and neck…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: JS111 in Patients With Advanced NSCLC Harboring EGFR Mutations [Phase 1, Phase 2]
A Phase 1/2 clinical trial of JS111 is recruiting for patients with advanced non-small cell lung cancer harboring EGFR mutations.
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: High-Dose Firmonertinib Combined With Bevacizumab and Intrathecal Pemetrexed in the Treatment of EGFR-Mutated Non-Small Cell Lung Cancer With Leptomeningeal Metastasis [Phase 2]
Phase 2 clinical trial evaluating high-dose Firmonertinib with Bevacizumab and intrathecal Pemetrexed for EGFR-mutated non-small cell lung c…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: Dose-Deescalated 3-Fraction Stereotactic Body Radiotherapy For Centrally Located Lung Cancer [Phase 1, Phase 2]
This update outlines a Phase 1/2 trial of dose-deescalated 3-fraction stereotactic body radiotherapy for centrally located non-small cell lu…
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CLINICAL_TRIALS other · 2025-05-14Clinical Trial Update: Study of IRX4204 With Erlotinib in Previously Treated Advanced NSCLC [Phase 1]
Phase 1 clinical trial update shows the study of IRX4204 combined with erlotinib in previously treated advanced non-small cell lung cancer h…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: MWA With or Without Furmonertinib for Early-Stage Non-Small Cell Lung Cancer [NA]
A clinical trial is evaluating microwave ablation with or without furmonertinib for early-stage non-small cell lung cancer. The study is cur…
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CLINICAL_TRIALS trial_result · 2025-05-13Clinical Trial Update: Phase I/II Trial of Alectinib and Bevacizumab in Patients With Advanced, Anaplastic Lymphoma Kinase (ALK)-Positive, Non-Small Cell Lung Cancer [Phase 1, Phase 2]
A Phase I/II study evaluating the combination of alectinib and bevacizumab in ALK-positive non-small cell lung cancer was terminated, with r…
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CLINICAL_TRIALS trial_result · 2025-05-13Clinical Trial Update: Phase 1/2 Study of APR-246 in Combination With Pembrolizumab in Subjects With Solid Tumor Malignancies [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating APR-246 in combination with pembrolizumab in solid tumors has completed enrollment with results posted…
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CLINICAL_TRIALS research · 2025-05-13Clinical Trial Update: Efficacy of Torque Teno Virus as a Biomarker for Predicting Treatment Response of Immune Checkpoint Inhibitor Therapy and Postoperative Outcome in NSCLC Patients
A clinical trial from the Medical University of Vienna is evaluating Torque Teno Virus as a biomarker to predict response to immune checkpoi…
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CLINICAL_TRIALS trial_result · 2025-05-13Clinical Trial Update: The Study of NC318 Alone or in Combination With Pembrolizumab in Patients With Advanced Non-small Cell Lung Cancer [Phase 2]
A Phase 2 study evaluating NC318 alone or in combination with pembrolizumab in adults with advanced non-small cell lung cancer is active but…
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FDA approval · 2025-05-13FDA Approved: DOCETAXEL — Original Application (Meitheal Pharmaceuticals Inc.)
FDA approves a generic docetaxel product under an original ANDA for Meitheal Pharmaceuticals Inc.
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CLINICAL_TRIALS research · 2025-05-12Clinical Trial Update: NAD+ Supplement（NMN）With Radioimmunotherapy in Advanced NSCLC [Phase 1]
A Phase 1 clinical trial is evaluating NAD+ precursor NMN in combination with radioimmunotherapy for advanced non-small cell lung cancer. Th…