Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors [Phase 1]
Phase 1 trial evaluating [225Ac]Ac-AKY-1189 for solid tumors is currently recruiting, including urothelial carcinoma of the bladder and trip…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Trial Investigating Visugromab and Nivolumab With or Without Docetaxel in 2L Treatment of Participants With Metastatic NSCLC [Phase 2]
Phase 2 clinical trial evaluating Visugromab with nivolumab, with or without docetaxel, for second-line metastatic non-squamous non-small ce…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Barriers and Facilitators of Persistence With Adjuvant Osimertinib
Clinical trial update examining barriers and facilitators to persistence with adjuvant osimertinib in non-small cell lung cancer.
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Divarasib Compared With Investigator's Choice of Immunotherapy or Observation in Participants With Resected Stage II-III KRAS G12C-Positive Non-Small Cell Lung Cancer (NSCLC) [Phase 3]
A Phase 3 trial in resected Stage II-III KRAS G12C-positive non-small cell lung cancer compares Divarasib with investigator's choice of immu…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: A Study to Compare ABP 234 and Keytruda® (Pembrolizumab) in Participants With Advanced or Metastatic Non-squamous Non-Small Cell Lung Cancer [Phase 3]
This document announces a Phase 3 clinical trial comparing ABP 234 to pembrolizumab (Keytruda) in patients with advanced or metastatic non-s…
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CLINICAL_TRIALS other · 2026-04-21Clinical Trial Update: Study of JDQ443 in Comparison With Docetaxel in Participants With Locally Advanced or Metastatic KRAS G12C Mutant Non-small Cell Lung Cancer [Phase 3]
Phase 3 trial evaluating JDQ443 versus docetaxel in locally advanced or metastatic KRAS G12C-mutant non-small cell lung cancer; the study is…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: CIMAvax-EGF With KRAS G12C Inhibitor for the Treatment of Advanced, KRAS G12C Mutated Non Small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial evaluating CIMAvax-EGF in combination with a KRAS G12C inhibitor for advanced KRAS G12C-mutated non-small cell lung…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies [Phase 1, Phase 2]
Phase 1/2 clinical trial of S241656 in RAS/MAPK mutation-positive malignancies is currently recruiting. The study targets non-small cell lun…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: A Study to Investigate the Safety and Efficacy of KQB368 as Monotherapy in Participants With Advanced Solid Malignancies [Phase 1]
Phase 1 study to assess safety and preliminary efficacy of KQB368 as monotherapy in participants with advanced solid malignancies; the trial…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: RATS Sleeve Lobectomy After Neo-Chemo-IO for NSCLC
A Shanghai Chest Hospital trial is evaluating robotic-assisted sleeve lobectomy after neoadjuvant chemoimmunotherapy for stage IIB to III no…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Phase I Study of [177Lu]Lu-DFC413 in Patients With Solid Tumors [Phase 1]
Phase I study update for the radiopharmaceutical [177Lu]Lu-DFC413 in patients with various solid tumors, currently recruiting.
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CLINICAL_TRIALS other · 2026-04-21Clinical Trial Update: Study of Itacitinib in Combination With Docetaxel in Subjects With Non-Small Cell Lung Cancer [Phase 2]
A Phase 2 study of itacitinib in combination with docetaxel for non-small cell lung cancer has been terminated.
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: RACE-2L: Real-World Assessment of Clinical Practice and Outcomes in Non-squamous NSCLC After Failure of Platinum-based Chemotherapy in Brazil
Real-world observational trial in Brazil evaluating treatment patterns and outcomes in non-squamous non-small cell lung cancer after platinu…
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CLINICAL_TRIALS other · 2026-04-21Clinical Trial Update: A Study of Ivonescimab in Combination With Dato-DXd or Osimertinib in People With Non-Small Cell Lung Cancer [Phase 1, Phase 2]
This clinical trial update notes ongoing Phase 1/2 studies evaluating Ivonescimab in combination with Dato-DXd or Osimertinib for non-small …
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: The Impact of Exercise on the Tumor Microenvironment in Patients With Lung Cancer [NA]
A University of Arizona-sponsored clinical trial is evaluating how exercise impacts the tumor microenvironment in patients with non-small ce…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: MK-3475A±Calderasib (MK-1084) in Completely Resected Stage IIA-IIIB (N2) KRAS G12Cm NSCLC (MK-1084-013) [Phase 3]
A Phase 3 trial evaluating pembrolizumab (MK-3475A) with or without Calderasib (MK-1084) in completely resected KRAS G12C-mutant non-small c…
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: Efficacy and Safety Study of Tisotumab Vedotin for Patients With Solid Tumors [Phase 2]
This Phase 2 trial update evaluates the efficacy and safety of tisotumab vedotin in solid tumors. It includes colorectal cancer, non-small c…
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: A Study of Tucidinostat Combined With Tislelizumab as First-line Treatment in Advanced NSCLC [Phase 2]
Phase 2 study evaluating tucidinostat in combination with tislelizumab as first-line treatment for advanced Non-Small Cell Lung Cancer has c…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer [Phase 3]
A Phase 3 trial evaluating first-line olomorasib with pembrolizumab, with or without chemotherapy, in advanced KRAS G12C-mutant non-small ce…
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: A Study of Atezolizumab in Combination With Epacadostat in Subjects With Previously Treated Stage IIIB or Stage IV Non-Small Cell Lung Cancer and Previously Treated Stage IV Urothelial Carcinoma [Phase 1]
Phase 1 study of atezolizumab in combination with epacadostat in previously treated non-small cell lung cancer and urothelial cancer; the tr…
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: A Study Evaluating the Efficacy and Safety of Divarasib Versus Sotorasib or Adagrasib in Participants With Previously Treated KRAS G12C-positive Advanced or Metastatic Non-Small Cell Lung Cancer [Phase 3]
A Phase 3 clinical trial comparing Divarasib to Sotorasib or Adagrasib in previously treated KRAS G12C-positive advanced or metastatic non-s…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: A Study Evaluating the Safety, Activity, and Pharmacokinetics of Divarasib as a Single Agent or in Combination With Other Anti-Cancer Therapies in Participants With Previously Untreated Advanced or Metastatic Non-Small Cell Lung Cancer With a KRAS G12C Mutation [Phase 1, Phase 2]
This is an ongoing Phase 1/2 clinical trial evaluating divarasib as a single agent or in combination with other anti-cancer therapies in pre…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: A Study of BL-B01D1 in Combination With Osimertinib Versus Osimertinib as First-Line Treatment in Patients With EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer(PANKU-Lung04) [Phase 3]
A Phase 3 clinical trial update describing a study of BL-B01D1 in combination with Osimertinib versus Osimertinib alone as first-line treatm…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Iparomlimab and Tuvonralimab Plus Chemotherapy Before Surgery for Stage III Lung Cancer [NA]
A clinical trial update notes a neoadjuvant regimen of Iparomlimab and Tuvonralimab plus chemotherapy before surgery for stage III non-small…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Evaluate the Safety and Efficacy of BLEX 404 Oral Liquid Combined With Pemetrexed + Cisplatin Therapy [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating the safety and efficacy of BLEX 404 oral liquid in combination with pemetrexed and cisplatin for no…