Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Taletrectinib Phase 2 Global Study in ROS1 Positive NSCLC [Phase 2]
Taletrectinib is being studied in a Phase 2 global trial for ROS1-positive non-small cell lung cancer, with the study currently active but n…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Osimertinib Combined With Savolitinib in the Treatment of NSCLC With Low Copy Number MET Amplification [Phase 2]
Phase 2 trial of osimertinib combined with savolitinib for non-small cell lung cancer with MET amplification; currently recruiting.
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Phase II Study Investigating the Combination of Encorafenib and Binimetinib in BRAF V600E Mutated Chinese Patients With Metastatic Non-Small Cell Lung Cancer [Phase 2]
Phase II trial update investigating the combination of encorafenib and binimetinib in Chinese patients with metastatic non-small cell lung c…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Neoadjuvant Sacituzumab Tirumotecan and Limertinib for Potentially Resectable Stage Ⅲ EGFR-mutant Non-small Cell Lung Cancer [Phase 2]
A Phase 2 neoadjuvant trial is investigating sacituzumab tirumotecan with limertinib for potentially resectable stage III EGFR-mutant non-sm…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Study of Dato-DXd Plus Pembrolizumab vs Pembrolizumab Alone in the First-line Treatment of Subjects With Advanced or Metastatic NSCLC Without Actionable Genomic Alterations [Phase 3]
An ongoing Phase 3 clinical trial comparing datopotamab deruxtecan plus pembrolizumab versus pembrolizumab alone as first-line treatment for…
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CLINICAL_TRIALS trial_result · 2026-01-06Clinical Trial Update: Combination Study of RMC-4630 and Sotorasib for NSCLC Subjects With KRASG12C Mutation After Failure of Prior Standard Therapies [Phase 2]
A Phase 2 trial evaluating the combination of RMC-4630 and sotorasib in KRAS G12C-mutant non-small cell lung cancer after prior therapies ha…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Postoperative Radiotherapy for Postoperative N2 Metastases of NSCLC in the Immunotherapy Era (Phase II) [Phase 4]
This clinical trial update describes an ongoing post-operative radiotherapy study for non-small cell lung cancer with N2 metastases in the i…
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CLINICAL_TRIALS trial_result · 2026-01-06Clinical Trial Update: A Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced Cancers [Phase 1]
Phase 1 study assessing safety and early efficacy of KFA115 alone and in combination with pembrolizumab in select advanced cancers; the tria…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: A Study Evaluating BAT3306 Compared With Keytruda® in NSCLC Cancer Participants [Phase 1]
A Phase 1 study evaluating BAT3306 compared with pembrolizumab (Keytruda) in patients with non-small cell lung cancer is currently recruitin…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Effects of a Visual Interactive LINE Chatbot on Self-Management of EGFR-TKI Related Side Effects in Patients With Lung Cancer [NA]
A clinical trial evaluating a visual interactive LINE chatbot to help patients with non-small cell lung cancer self-manage EGFR-TKI related …
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: PEMBRO-K : Evaluation of Pembrolizumab Therapeutic Pharmacological Monitoring Benefit in NSCLC
This clinical trial update describes the PEMBRO-K study evaluating therapeutic pharmacological monitoring with pembrolizumab in non-small ce…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: NK-cell Therapy Combined With PD-1 Antibody and Platinum-Based Chemotherapy as Neoadjuvant Therapy in Resectable NSCLC [Phase 1]
Phase 1 clinical trial evaluating neoadjuvant therapy for resectable non-small cell lung cancer using a combination of NK-cell therapy, a PD…
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CLINICAL_TRIALS trial_result · 2026-01-06Clinical Trial Update: Firmonertinib Combined With Definitive Radiotherapy in Stage III Unresectable EGFR Uncommon Mutant Pulmonary Adenocarcinoma [Phase 2]
Phase 2 trial update evaluating Firmonertinib combined with definitive radiotherapy for stage III unresectable EGFR uncommon mutant non-smal…
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CLINICAL_TRIALS trial_result · 2026-01-05Clinical Trial Update: A Study of Gimistotug (BGB-A445) in Combination With Other Investigational Agents in Participants With Non-Small Cell Lung Cancer [Phase 2]
Phase 2 study evaluating Gimistotug (BGB-A445) in combination with other investigational agents for non-small cell lung cancer has completed…
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: Adaptive Adjuvant Sintilimab Therapy Guided by MRD (ADAPT Lung) [Phase 2]
An ongoing Phase 2 trial (ADAPT Lung) evaluating adaptive adjuvant sintilimab therapy guided by minimal residual disease in non-small cell l…
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: Positron Emission Tomography (PET) Guided Stereotactic Body Radiation Therapy for the Treatment of Oligoprogressive Non-small Cell Lung Cancer, Melanoma, and Renal Cell Carcinoma [Phase 2]
A Phase 2 clinical trial is evaluating PET-guided stereotactic body radiation therapy for oligoprogressive disease in non-small cell lung ca…
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CLINICAL_TRIALS trial_result · 2026-01-05Clinical Trial Update: C-TIL051 in Non-Small Cell Lung Cancer [Phase 1]
A Phase 1 clinical trial evaluating C-TIL051 for metastatic non-small cell lung cancer has been terminated.
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: Validation of the TheraSure CNI-Monitor Under Immuno-checkpoint-therapy (Hereinafter: "Immunotherapy") in NSCLC in Palliative Therapy
This entry reports a trial validating the TheraSure CNI-Monitor in non-small cell lung cancer patients undergoing immunotherapy in palliativ…
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: A Multi-centre Chart Review Study of Stage I-III Non-Small Cell Lung Cancer in China
This clinical trial update describes a planned multi-centre chart review study of stage I-III non-small cell lung cancer in China; recruitme…
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: Study of ZG005 Combined With Gecacitinib in Patients With Advanced Non-Small Cell Lung Cancer [Phase 1, Phase 2]
The document reports a Phase 1/Phase 2 clinical trial evaluating ZG005 in combination with Gecacitinib in patients with advanced non-small c…
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: Locally Advanced NSCLC Treated With Radiochemotherapy: Phase 2 Study on the Value of a Stereotactic Boost [Phase 2]
A Phase 2 study is evaluating radiochemotherapy with a stereotactic boost for locally advanced non-small cell lung cancer and is currently r…
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CLINICAL_TRIALS trial_result · 2026-01-02Clinical Trial Update: Study of Interest of Personalized Radiotherapy Dose Redistribution in Patients With Stage III NSCLC [Phase 2]
Phase 2 trial evaluating personalized radiotherapy dose redistribution for stage III non-small cell lung cancer has completed enrollment.
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CLINICAL_TRIALS trial_result · 2026-01-02Clinical Trial Update: Dynamics of 18-FDG Uptake in Stage III/IV Non Small Cell Lung Cancer During First Line Pembrolizumab Treatment [NA]
This clinical trial update analyzes how 18-FDG uptake changes over time in patients with stage III/IV non-small cell lung cancer treated wit…
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CLINICAL_TRIALS research · 2026-01-02Clinical Trial Update: The CCANED-CIPHER Study: Early Cancer Detection and Treatment Response Monitoring Using AI-Based Platelet and Immune Cell Transcriptomic Profiling
This clinical trial update describes the CCANED-CIPHER study, an ongoing investigation using AI-based transcriptomic profiling of platelets …
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CLINICAL_TRIALS research · 2026-01-02Clinical Trial Update: Imaging and Blood-Based Biomarkers for the Evaluation of Early Signs of Myocardial Injury After Thoracic Radiation Therapy
This clinical trial update from Ohio State University Comprehensive Cancer Center describes evaluating imaging and blood-based biomarkers to…