Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: A Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC) [Phase 2]
This Phase 2 trial aims to evaluate adverse events and pharmacokinetics of Telisotuzumab Vedotin as a standalone therapy in adults with prev…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: DeniLA: Comprehensive Demographics and Clinical Profile of NSCLC Patients: Analyzing Guideline-Concordant Care in First-line Treatment Patterns
This clinical trial update profiles demographics and clinical characteristics of non-small cell lung cancer patients and analyzes guideline-…
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CLINICAL_TRIALS trial_result · 2026-02-23Clinical Trial Update: Study to Evaluate Adverse Events, Optimal Dose, and Change in Disease Activity, With Livmoniplimab in Combination With Budigalimab Plus Chemotherapy Versus IV Infused Pembrolizumab Plus Chemotherapy in Adult Participants With Untreated Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC) [Phase 2, Phase 3]
This Phase 2/Phase 3 trial compares Livmoniplimab plus Budigalimab with chemotherapy versus Pembrolizumab plus chemotherapy as first-line tr…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: A First-in-human Study of PRTH-101 Monotherapy +/- Pembrolizumab in Subjects With Advanced Malignancies [Phase 1]
A first-in-human Phase 1 study of PRTH-101 alone or with pembrolizumab in patients with advanced malignancies is recruiting, including non-s…
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CLINICAL_TRIALS trial_result · 2026-02-23Clinical Trial Update: A Study to Learn About How Different Amounts of the Study Medicine PF-07826390 Act in the Body of People With Cancer When Taken Alone or With Other Anti-cancer Medicines. [Phase 1]
Phase 1 study of PF-07826390 in cancer patients, including non-small cell lung cancer, was terminated; the trial evaluated different doses o…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: A Study of Trastuzumab Deruxtecan in People With Non-Small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial evaluating trastuzumab deruxtecan for non-small cell lung cancer is currently recruiting, including stage II, IIIA,…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Immunotherapy Consolidation After Radical Treatment of Synchronous Oligo-metastatic NSCLC [Phase 2]
This clinical trial update describes a Phase 2 study evaluating immunotherapy as consolidation therapy after radical treatment for synchrono…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Lazertinib & Tepotinib for EGFR Mutant NSCLC in MET Overexpressed or Amplified Who Progressed After Lazertinib Treatment [Phase 2]
A Phase 2 trial evaluating the combination of lazertinib and tepotinib for EGFR-mutant metastatic non-small cell lung cancer with MET overex…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Pre-operative Tumor Treating Fields in Patients With Resectable Lung Cancer [NA]
A clinical trial evaluating pre-operative tumor treating fields in patients with resectable non-small cell lung cancer; the study is not yet…
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CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: Sarcopenia and CRP-TyG Index (CTI) as Predictors of Immunotherapy Response in Metastatic Non-Small Cell Lung Cancer
This completed clinical trial investigated whether sarcopenia and the CRP-TyG (CTI) index can predict response to immunotherapy in metastati…
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CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: Nivolumab Plus Cisplatin/Pemetrexed or Cisplatin/Gemcitabine as Induction in Resectable Non-Small Cell Lung Cancer [Phase 2]
Phase 2 trial evaluating nivolumab with induction chemotherapy in resectable non-small cell lung cancer was terminated, and results have bee…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating the safety and efficacy of a mesothelin-targeting logic-gated CAR T therapy in adults with solid tumors …
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Phase 1 Study Of Izalontamab Brengitecan + Adagrasib In NSCLC - The IZA-A Trial [Phase 1]
Phase 1 clinical trial evaluating Izalontamab Brengitecan in combination with Adagrasib for non-small cell lung cancer; the study is current…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Ascending Doses of Ceralasertib in Combination With Chemotherapy and/or Novel Anti Cancer Agents [Phase 1, Phase 2]
Clinical trial update on ascending doses of ceralasertib in combination with chemotherapy or other anti-cancer agents in advanced solid mali…
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CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: Poziotinib in EGFR Exon 20 Mutant Advanced NSCLC [Phase 2]
Phase 2 trial of poziotinib for EGFR exon 20-mutant or ERBB2-mutant advanced non-small cell lung cancer was terminated.
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Early Rebiopsy to Identify Biomarkers of Tumor Cell Survival Following EGFR, ALK, ROS1 or BRAF TKI Therapy
This clinical trial update describes a study evaluating early rebiopsy to identify biomarkers of tumor cell survival after EGFR, ALK, ROS1, …
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CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: First in Human Study of AZD9592 in Solid Tumors [Phase 1]
First-in-human Phase 1 study of AstraZeneca’s AZD9592 in solid tumors is recruiting to evaluate safety, tolerability, and preliminary dosing…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: A Study of ITC-6146RO in Patients With Advanced or Metastatic Cancer Who Have Failed Standard Therapy [Phase 1]
Phase 1 study of ITC-6146RO in patients with advanced or metastatic cancers after standard therapy; the trial is not yet recruiting.
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Onco-primary Care Networking to Support TEAM-based Care [NA]
Clinical trial update noting that the Duke University study on oncology-primary care networking to support TEAM-based care is currently ACTI…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Study of AZD5305 as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Malignancies [Phase 1, Phase 2]
AZD5305 is being evaluated as a monotherapy and in combination with anti-cancer agents in a Phase 1/2 trial for multiple advanced solid mali…
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CLINICAL_TRIALS trial_result · 2026-02-19Clinical Trial Update: Feasibility and Safety of IMP321 (Eftilagimod Alpha) for Advanced Stage Solid Tumors [Phase 1]
A Phase 1 trial assessing IMP321 (eftilagimod alpha) for advanced solid tumors reports feasibility and safety findings.
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Phase 1/2 Study Evaluating MCLA-129, a Human Anti-EGFR, Anti-c-MET Bispecific Antibody, in Advanced NSCLC and Other Solid Tumors, Alone and in Combination [Phase 1, Phase 2]
Phase 1/2 trial update evaluating MCLA-129, a bispecific anti-EGFR and anti-c-MET antibody, in advanced non-small cell lung cancer and other…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Testing the Safety of Dapagliflozin Prior to Surgery for the Treatment of Patients With Stage IA Lung Adenocarcinoma [EARLY_Phase 1]
This early-phase 1 trial evaluates the safety of dapagliflozin given before surgery in patients with Stage IA lung adenocarcinoma (a form of…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Beating Lung Cancer in Ohio Protocol in Improving Survival in Patients With Stage IV Non-Small Cell Lung Cancer [NA]
A clinical trial sponsored by Ohio State University Comprehensive Cancer Center is recruiting to test a protocol for improving survival in p…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: 177Lu-anti-PD-L1 sdAb in Metastatic Solid Tumors [EARLY_Phase 1]
Early-phase clinical trial investigating a radiolabeled anti-PD-L1 single-domain antibody (177Lu-anti-PD-L1 sdAb) in metastatic solid tumors…