Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Fluorine-18-AlphaVBeta6-Binding Peptide Positron Emission Tomography in Metastatic Non-Small Cell Lung Cancer [Phase 1]
This Phase 1 trial is evaluating a Fluorine-18 labeled AlphaVbeta6-binding peptide as a PET imaging agent for metastatic non-small cell lung…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Whole Body HER2 Quantification With 89Zr-Trastuzumab PET/CT to Asses Zr-trastuzumab Accumulation in HER2-mutated and HER2-overexpressing Metastatic Non-small Cell Lung Cancer [Phase 1]
A Phase 1 clinical trial is investigating whole-body quantification of HER2 with 89Zr-trastuzumab PET/CT to assess tracer accumulation in HE…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: A Study to Compare the Efficacy and Safety of Entrectinib and Crizotinib in Participants With Advanced or Metastatic ROS1 Non-small Cell Lung Cancer (NSCLC) With and Without Central Nervous System (CNS) Metastases [Phase 3]
A Phase 3 clinical trial comparing entrectinib with crizotinib in patients with advanced or metastatic ROS1-positive non-small cell lung can…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: DETERMINE Trial Treatment Arm 07: Dabrafenib in Combination With Trametinib in Adult, Paediatric and Teenage/Young Adult Patients With BRAF V600 Mutation-Positive Cancers. [Phase 2, Phase 3]
The DETERMINE trial's Arm 07 is studying dabrafenib plus trametinib in patients with BRAF V600 mutation-positive cancers across age groups; …
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Promoting Immunotherapy Efficacy With Low-Dose Liver RT [NA]
A clinical trial evaluating whether low-dose liver radiotherapy can boost immunotherapy efficacy in non-small cell lung cancer, melanoma, an…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Study of Three Endpoints to Assess the Benefit of Rehabilitation in Patients With Advanced Non-small Cell Lung Cancer Controlled After at Least 6 Months of Systemic Treatment
An upcoming clinical trial evaluating three endpoints to assess the benefit of rehabilitation in patients with advanced non-small cell lung …
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Sublobar Wedge Resection or Stereotactic Radiotherapy Treatment of High-risk Patients With Early-stage Lung Cancer [NA]
A clinical trial comparing sublobar wedge resection versus stereotactic radiotherapy for high-risk patients with early-stage non-small cell …
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Molecularly Targeted Radionuclide Therapy Via the Integrin Alphavbeta6 [Phase 1]
Phase 1 clinical trial using a molecularly targeted radionuclide therapy directed at integrin alphavbeta6 for metastatic non-small cell lung…
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FDA label_change · 2026-02-26FDA Approved: ENSACOVE — Supplemental Application (Xcovery Holdings, Inc.)
FDA approved a supplemental application for ENSACOVE (ensartinib) to update the labeling.
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CLINICAL_TRIALS trial_result · 2026-02-25Clinical Trial Update: PRO1107 in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
The Phase 1/2 PRO1107 trial in advanced solid tumors, including endometrial and ovarian cancers, has been terminated.
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: A Study of NVL-330 in Patients With Advanced or Metastatic HER2-altered NSCLC (HEROEX-1) [Phase 1]
A Phase 1 study (HEROEX-1) of NVL-330 in patients with advanced or metastatic HER2-altered non-small cell lung cancer is currently recruitin…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Image-Guided Hypofractionated Radiation Therapy With Stereotactic Body Radiation Therapy Boost and Combination Chemotherapy in Treating Patients With Stage II-III Non-Small Cell Lung Cancer That Cannot Be Removed By Surgery [NA]
This clinical trial update outlines a study of image-guided hypofractionated radiation therapy with a stereotactic body radiation therapy bo…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: PD-1 Inhibitor and Chemotherapy With Concurrent Irradiation at Varied Tumour Sites in Advanced Non-small Cell Lung Cancer [Phase 3]
A Phase 3 clinical trial evaluating a PD-1 inhibitor with chemotherapy and concurrent irradiation for advanced non-small cell lung cancer; t…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: REPotrectinib in ROS1-positive Non-small Cell Lung Cancer Patients With Active Brain mEtastasis [Phase 2]
Phase 2 trial update for repotrectinib in ROS1-positive non-small cell lung cancer patients with active brain metastases; currently recruiti…
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CLINICAL_TRIALS other · 2026-02-25Clinical Trial Update: Fecal Microbiota Transplant(FMT) Combination With Tislelizumab in Advanced or Metastatic NSCLC [Phase 2]
Phase 2 clinical trial evaluating fecal microbiota transplant in combination with tislelizumab for advanced or metastatic non-small cell lun…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: A Study of TAK-788 in Adults With Non-Small Cell Lung Cancer [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study of TAK-788 in adults with non-small cell lung cancer, currently active but not recrui…
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CLINICAL_TRIALS other · 2026-02-25Clinical Trial Update: A Phase 1, Multicenter Imaging Study of LNTH-2403 in Participants With Locally Advanced or Metastatic Solid Tumors. [Phase 1]
Phase 1 multicenter imaging trial update for LNTH-2403 in locally advanced or metastatic solid tumors; currently NOT_YET_RECRUITING.
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CLINICAL_TRIALS trial_result · 2026-02-24Clinical Trial Update: Bevacizumab Combined With Double Doses of Icotinib in Advanced NSCLC Patients With EGFR L858R Mutation [Phase 2]
Phase 2 trial evaluating bevacizumab combined with double doses of icotinib in advanced non-small cell lung cancer with EGFR L858R mutation …
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Cemiplimab and Fianlimab Before Surgery for the Treatment of Stage IB-IIIB Non-Small Cell Lung Cancer [Phase 2]
Phase 2 trial evaluating the combination of cemiplimab and fianlimab before surgery for stage IB-IIIB non-small cell lung cancer, currently …
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CLINICAL_TRIALS trial_result · 2026-02-24Clinical Trial Update: Understanding the Post-Surgical Non-Small Cell Lung Cancer Patient's Symptom Experience [NA]
A completed clinical trial update reports results related to symptoms and self-efficacy in post-surgical non-small cell lung cancer patients…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: A Study to Investigate Safety and Tolerability of TransCon IL-2 β/γ Alone or in Combination With Pembrolizumab and/or TransCon TLR7/8 Agonist or Other Anticancer Therapies in Adult Participants With Locally Advanced or Metastatic Solid Tumor Malignancies [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study evaluating the safety and tolerability of TransCon IL-2 β/γ alone or in combination w…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1 [Phase 3]
A Phase 3 clinical trial evaluating Ivonescimab as first-line therapy for metastatic Non-Small Cell Lung Cancer in patients with high PD-L1 …
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Self-Management Survivorship Care in Stage I-III Non-small Cell Lung Cancer or Colorectal Cancer [Phase 3]
An update on a Phase 3 trial evaluating self-management survivorship care for stage I-III non-small cell lung cancer and colorectal cancer.
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CLINICAL_TRIALS trial_result · 2026-02-23Clinical Trial Update: Study of REGN 2810 Compared to Platinum-Based Chemotherapies in Participants With Metastatic Non-Small Cell Lung Cancer (NSCLC) [Phase 3]
A Phase 3 study comparing cemiplimab (REGN2810) to platinum-based chemotherapy in metastatic non-small cell lung cancer has completed.
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CLINICAL_TRIALS withdrawal · 2026-02-23Clinical Trial Update: CISH Inactivated TILs in the Treatment of NSCLC [Phase 1, Phase 2]
A Phase 1/2 trial evaluating CISH-inactivated tumor-infiltrating lymphocytes for non-small cell lung cancer has been withdrawn.