Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: An Open-Label, Single-Arm, Dose-Escalation Phase I Study Evaluating the Safety, Tolerability, and Preliminary Efficacy of EDB-102 in Patients With EGFR L858R-Mutant, Third-Generation TKI-Resistant Advanced Non-Small Cell Lung Cancer With Liver Metastases [Phase 1]
This is a Phase I open-label, dose-escalation study of EDB-102 evaluating safety, tolerability, and preliminary efficacy in EGFR L858R-mutan…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Necitumumab and Trastuzumab in Combination With Osimertinib for the Treatment of Refractory Epidermal Growth Factor Receptor (EGFR)-Mutated Stage IV Non-small Cell Lung Cancer [Phase 1, Phase 2]
Phase 1/2 clinical trial update evaluating the combination of necitumumab, trastuzumab, and osimertinib for refractory EGFR-mutated stage IV…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: The Safety, Dosimetry and Efficacy of 177Lu-INN805 in Patients With Malignant Solid Tumors [EARLY_Phase 1]
This early-phase (Phase 1) trial assesses the safety, dosimetry, and preliminary efficacy signals of the radiopharmaceutical 177Lu-INN805 in…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Pemetrexed-free vs. Pemetrexed-based Immunochemotherapy in Metastatic TTF-1 Negative Lung Adenocarcinoma [Phase 4]
Phase 4 clinical trial comparing pemetrexed-free versus pemetrexed-based immunochemotherapy in metastatic TTF-1 negative lung adenocarcinoma…
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CLINICAL_TRIALS trial_result · 2026-03-10Clinical Trial Update: Daratumumab in STK11 Mutated NSCLC [Phase 2]
A Phase 2 clinical trial evaluating daratumumab in non-small cell lung cancer with STK11/LKB1 mutations has completed.
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Phase III, Multicenter, Randomized Controlled Clinical Study of Three-Dimensional Radiotherapy for Primary Tumors in Non-Oligometastatic Stage IV Non-Small Cell Lung Cancer [NA]
A multicenter Phase III randomized trial from Guizhou Medical University evaluating three-dimensional radiotherapy for primary tumors in non…
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CLINICAL_TRIALS trial_result · 2026-03-10Clinical Trial Update: A Tool for Improving the Shared Decision-making Process in Patients With Non-small Cell Lung Cancer [NA]
Clinical trial update describing a Mayo Clinic-sponsored study that evaluates a decision-support tool to improve shared decision-making for …
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Efficacy and Safety of HGXJT in Bone Metastatic NSCLC Patients [NA]
Clinical trial update on HGXJT for bone-metastatic non-small cell lung cancer, currently recruiting.
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: The CyberChallenge Trial How Much is Too Much - What is the Role of Cyberknife Radiosurgery in Patients With Multiple Brain Metastases? [NA]
This clinical trial update discusses the role of CyberKnife radiosurgery for patients with multiple brain metastases, including individuals …
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CLINICAL_TRIALS trial_result · 2026-03-09Clinical Trial Update: Pembrolizumab and Stereotactic Radiosurgery for Melanoma or Non-Small Cell Lung Cancer Brain Metastases [Phase 1]
This phase 1 study assessed pembrolizumab in combination with stereotactic radiosurgery for patients with brain metastases from melanoma or …
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors [Phase 1]
A Phase 1 clinical trial from AstraZeneca evaluating a KRAS G12D-targeted TCR-T cell therapy in adults with unresectable, advanced, or metas…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Therapy for Advanced NSCLC With EGFR 19delins Mutation [EARLY_Phase 1]
An early-phase (Phase 1) study of an investigational therapy for advanced non-small cell lung cancer with EGFR 19delins mutation. The trial …
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CLINICAL_TRIALS trial_result · 2026-03-09Clinical Trial Update: Study of AK119 and AK112 With or Without Chemotherapy for NSCLC Patients [Phase 1, Phase 2]
A Phase 1/2 trial evaluating AK119 and AK112 with or without chemotherapy for non-small cell lung cancer has been terminated.
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: AK112 and AK104 With or Without Chemotherapy in Advanced Non-small Cell Lung Cancer [Phase 1, Phase 2]
This clinical trial update discusses the Phase 1/Phase 2 study of AK112 and AK104, with or without chemotherapy, in advanced non-small cell …
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: A Study of YL202 in Patients With Advanced Solid Tumors [Phase 2]
A Phase 2 trial of YL202 in patients with advanced solid tumors is currently recruiting, including non-small cell lung cancer, colorectal ca…
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CLINICAL_TRIALS other · 2026-03-09Clinical Trial Update: AK112 in Advanced Non-Small Cell Lung Cancer [Phase 3]
This entry provides an update on the AK112 trial in advanced non-small cell lung cancer, indicating the Phase 3 study is currently active bu…
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CLINICAL_TRIALS trial_result · 2026-03-09Clinical Trial Update: Pulmonary Magnetic Resonance-guided Online Adaptive Radiotherapy of Locally Advanced Non-Small Cell Lung Cancer [NA]
This clinical trial update describes a study of pulmonary MR-guided online adaptive radiotherapy for locally advanced non-small cell lung ca…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating RAS(ON) inhibitors in patients with advanced non-small cell lung cancer harboring KRAS, NRAS, or HR…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Multiple Targeted Therapies as Treatments for Participants With Non-Small Cell Lung Cancer (NSCLC) [Phase 2, Phase 3]
A Phase 2/3 clinical trial sponsored by Hoffmann-La Roche is evaluating the efficacy and safety of multiple targeted therapies for non-small…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Study to Evaluate the Efficacy and Safety of Adjuvant Tislelizumab in High-Risk Stage I NSCLC [Phase 2]
Phase 2 trial to evaluate adjuvant tislelizumab in high-risk stage I non-small cell lung cancer. The study is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: ctDNA-MRD Guided Escalation of Ivonescimab and Docetaxel in Advanced NSCLC With Long-Term Responses to First-line Immunotherapy (CR1STAL-Adaptive) [Phase 2]
A Phase 2 clinical trial investigates whether using ctDNA-minimal residual disease status to guide escalation of Ivonescimab plus Docetaxel …
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CLINICAL_TRIALS trial_result · 2026-03-09Clinical Trial Update: Image-Guided, Intensity-Modulated Photon or Proton Beam Radiation Therapy in Treating Patients With Stage II-IIIB Non-small Cell Lung Cancer [Phase 1, Phase 2]
This ClinicalTrials.gov entry outlines a Phase 1/2 study evaluating image-guided, intensity-modulated photon or proton beam radiation therap…
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK 1/2/3 (Trk A/B/C), ROS1, or ALK Gene Rearrangements (Fusions) [Phase 2]
Phase 2 basket study evaluating entrectinib in solid tumors harboring NTRK1/2/3, ROS1, or ALK gene rearrangements; the study is listed as Ac…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Tocilizumab, Ipilimumab, and Nivolumab for the Treatment of Advanced Melanoma, Non-Small Cell Lung Cancer, or Urothelial Carcinoma [Phase 2]
Phase 2 clinical trial update evaluating a triple combination of tocilizumab, ipilimumab, and nivolumab for advanced melanoma, non-small cel…
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: Liquid Biopsy Genotyping Using Oncomine Precision Assay GX in Advanced NSCLC [NA]
A completed clinical trial evaluating liquid biopsy genotyping using the Oncomine Precision Assay GX in advanced Non-Small Cell Lung Cancer.