Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: A Study to Compare Pharmacokinetics, Efficacy, Safety, and Immunogenicity of MB12 (Proposed Pembrolizumab Biosimilar) to Keytruda® in Non-small Cell Lung Cancer (BENITO Study) [Phase 3]
Phase 3 clinical trial comparing MB12, a proposed pembrolizumab biosimilar, to Keytruda in non-small cell lung cancer to assess pharmacokine…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: First-in-human Study of Interferon-y PET Imaging to Assess Response to Immunotherapy [Phase 1]
This clinical trial update describes a first-in-human Phase 1 study of an interferon-gamma PET imaging tracer to assess immunotherapy respon…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: The Effect of Toripalimab Plus Radiotherapy in Patients With Operable Stage II-IIIA (N+) Non Small Cell Lung Cancer [Phase 2]
This document reports a Phase 2 trial evaluating toripalimab plus radiotherapy for operable stage II-IIIA (N+) non-small cell lung cancer; e…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: IBI351 Plus Cetuximab β in Untreated Advanced Non-small Cell Lung Cancer With KRAS G12C Mutation [Phase 2]
Phase 2 clinical trial investigating IBI351 in combination with Cetuximab beta for untreated advanced non-small cell lung cancer with KRAS G…
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CLINICAL_TRIALS trial_result · 2026-03-11Clinical Trial Update: NBTXR3 and Radiation Therapy for the Treatment of Inoperable Recurrent Non-small Cell Lung Cancer [Phase 1]
A Phase 1 clinical trial update evaluates NBTXR3 hafnium oxide nanoparticles in combination with radiation therapy for inoperable recurrent …
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Cardiovascular Injury and Cardiac Fitness in Locally Advanced Non-Small Cell Lung Cancer Patients Receiving Model Based Personalized Chemoradiation [NA]
An ongoing clinical trial update examining cardiovascular injury and cardiac fitness in locally advanced non-small cell lung cancer patients…
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CLINICAL_TRIALS trial_result · 2026-03-11Clinical Trial Update: A Study Evaluating the Safety and Efficacy of Neoadjuvant and Adjuvant Tiragolumab Plus Atezolizumab, With or Without Platinum-Based Chemotherapy, in Participants With Previously Untreated Locally Advanced Resectable Stage II, IIIA, or Select IIIB Non-Small Cell Lung Cancer [Phase 2]
Phase 2 study evaluating tiragolumab plus atezolizumab with or without platinum chemotherapy in untreated locally advanced resectable non-sm…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: A Phase III Study of HS-20093 Injection Combined With Adebrelimab Versus Docetaxel in Previously Treated Patients With Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer Without Actionable Genomic Alterations [Phase 3]
Announcement of a Phase III trial evaluating HS-20093 injection plus adebrelimab versus docetaxel in previously treated advanced or metastat…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: HEARTS Trial for Thoracic Cancers [Phase 2]
HEARTS is a Phase 2 clinical trial targeting thoracic cancers, including non-small cell lung cancer, esophageal cancer, esophagogastric canc…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Liquid Biopsy Based NGS in Newly Diagnosed NSCLC [NA]
A clinical trial evaluating liquid biopsy-based next-generation sequencing in newly diagnosed non-small cell lung cancer is currently active…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: A Study to Assess Adverse Events and Change in Disease Activity of Intravenous (IV) Telisotuzumab Adizutecan Compared to Standard of Care in Adult Participants With Locally Advanced or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer [Phase 2, Phase 3]
Clinical trial update for an ongoing Phase 2/3 study comparing Telisotuzumab Adizutecan to standard of care in adults with EGFR-mutated loca…
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CLINICAL_TRIALS trial_result · 2026-03-11Clinical Trial Update: Tunlametinib Combination Therapy in KRAS-Mutated Unresectable Locally Advanced or Metastatic Non-Small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial assessing tunlametinib in combination therapy for KRAS-mutated unresectable locally advanced or metastatic non-smal…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Neoadjuvant and Adjuvant Treatment in Resectable Non-small Cell Lung Cancer [Phase 2]
AstraZeneca is conducting a Phase 2 study of neoadjuvant and adjuvant therapy for resectable non-small cell lung cancer, currently recruitin…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Pembrolizumab Plus Bevacizumab and Chemotherapy for Non-Squamous NSCLC Patients [Phase 2]
A Phase 2 trial evaluating pembrolizumab plus bevacizumab and chemotherapy for non-small cell lung cancer is currently active but not recrui…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: GT103 in Combination With Pembrolizumab for the Treatment of Advanced or Metastatic STK11 Mutant Non-Small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial evaluating GT103 in combination with pembrolizumab for advanced or metastatic STK11-mutant non-small cell lung canc…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Role of Gut Microbiome and Fecal Transplant on Medication-Induced GI Complications in Patients With Cancer [Phase 1]
A Phase 1 clinical trial at MD Anderson Cancer Center is studying whether modifying the gut microbiome via fecal transplantation can reduce …
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: ORIENT-31 Regimen in Combination With SBRT for EGFR-mutant Metastatic NSCLC After First-line Third-generation EGFR-TKIs [Phase 2]
This entry documents a Phase 2 clinical trial evaluating the ORIENT-31 regimen in combination with SBRT for EGFR-mutant metastatic non-small…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: PhI/II Study of Amivantamab and Tepotinib Combo in MET-altered Non-small Cell Lung Cancer [Phase 1, Phase 2]
A Phase I/II clinical trial evaluating the combination of amivantamab and tepotinib for MET-altered non-small cell lung cancer is currently …
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Study of BPI-572270 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS [Phase 1, Phase 2]
Betta Pharmaceuticals' BPI-572270 is being studied in Phase 1/2 trials for advanced solid tumors with specific RAS mutations, including non-…
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CLINICAL_TRIALS other · 2026-03-11Clinical Trial Update: Evaluation of Impedance Cardiography for Assessing Hemodynamic Shifts in Patients With LA-NSCLC During Treatment.
A clinical trial update describing an observational evaluation of impedance cardiography to monitor hemodynamic shifts in patients with loca…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: A Global Phase II/III Clinical Study to Evaluate the Efficacy and Safety of HLX43 Monotherapy or HLX43 in Combination With HLX07 Versus Docetaxel in Advanced or Metastatic Squamous Non-Small Cell Lung Cancer [Phase 2, Phase 3]
A global Phase II/III trial evaluating HLX43 as a monotherapy or in combination with HLX07 versus docetaxel in advanced or metastatic squamo…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: REZILIENT3 (REsearching ZIpaLertinib In Egfr Non-small Cell Lung Cancer Tumors) [Phase 3]
A Phase 3 trial (REZILIENT3) evaluating zipalertinib for advanced or metastatic EGFR exon 20 insertion non-small cell lung cancer is current…
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CLINICAL_TRIALS trial_result · 2026-03-10Clinical Trial Update: Understanding Non-small Cell Lung Cancer Patient Characteristics, Treatment Patterns and Outcomes
A completed AstraZeneca-sponsored clinical trial update examining patient characteristics, treatment patterns, and outcomes in non-small cel…
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CLINICAL_TRIALS trial_result · 2026-03-10Clinical Trial Update: A Study to Learn About Lorlatinib in Patients With Non-Small Cell Lung Cancer Which Could Not Be Controlled
Results from a completed study evaluating lorlatinib in patients with non-small cell lung cancer that could not be controlled have been post…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Phase I Trial of Defactinib and VS-6766. [Phase 1]
A Phase I clinical trial evaluating the combination of defactinib and VS-6766 across multiple solid tumors, including non-small cell lung ca…