Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2014-02-27Clinical Trial Update: Paclitaxel, Carboplatin, and Radiation Therapy in Treating Patients Who Are Undergoing Surgery for Stage III Non-Small Cell Lung Cancer [Phase 2]
Phase 2 trial evaluating paclitaxel, carboplatin, and radiation therapy in patients undergoing surgery for stage III non-small cell lung can…
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CLINICAL_TRIALS trial_result · 2014-02-27Clinical Trial Update: Determine MTD and to Evaluate pk, Safety/Tolerability and Efficacy Profiles of Hocena® in NSCLC Subjects [Phase 1]
Phase 1 study to determine the maximum tolerated dose and evaluate pharmacokinetics, safety, tolerability, and preliminary efficacy of Hocen…
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CLINICAL_TRIALS trial_result · 2014-02-25Clinical Trial Update: Afatinib Plus Nimotuzumb for NSCLC [Phase 1, Phase 2]
Clinical trial update on a Phase 1/2 study evaluating the combination of afatinib and nimotuzumab for non-small cell lung cancer, with curre…
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CLINICAL_TRIALS trial_result · 2014-02-24Clinical Trial Update: Theranostic Tool During Erlotinib Treatment in Non-small Cell Lung Cancer Patient [Phase 2]
Phase 2 clinical trial investigating a theranostic tool used during erlotinib treatment for patients with metastatic or recurrent non-small …
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CLINICAL_TRIALS trial_result · 2014-02-19Clinical Trial Update: Intermittent and Maintenance of Erlotinib in Combination With Pemetrexed/Carboplatin in Ⅲb/IV Non Small Cell Lung Cancer With Epidermal Growth Factor Receptor (EGFR) Mutation [Phase 2]
This document reports a Phase 2 trial update evaluating intermittent and maintenance erlotinib plus pemetrexed/carboplatin in advanced EGFR-…
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CLINICAL_TRIALS research · 2014-02-17Clinical Trial Update: Icotinib Combined With WBRT For NSCLC Patients With Brain Metastases and EGFR Mutation [Phase 1, Phase 2]
Clinical trial update reporting Phase 1/2 evaluation of icotinib combined with whole-brain radiotherapy in EGFR-mutant non-small cell lung c…
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CLINICAL_TRIALS trial_result · 2014-02-17Clinical Trial Update: Dose Escalation Of Icotinib In Previously Treated Patients With Routine Dose [Phase 4]
Phase 4 dose-escalation study evaluating icotinib in previously treated non-small cell lung cancer patients.
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FDA approval · 2014-02-14FDA Approved: XALKORI — Supplemental Application (Pfizer Laboratories Div Pfizer Inc)
FDA approved a supplemental application for XALKORI (crizotinib) submitted by Pfizer Laboratories Div Pfizer Inc.
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CLINICAL_TRIALS trial_result · 2014-02-11Clinical Trial Update: Combination of Weekly Chest Radiotherapy and Oral Navelbine for the Palliation of Advanced Non Small Cell Lung Cancer: A Phase I Study [Phase 1, Phase 2]
This clinical trial update reports a Phase I/II study evaluating weekly chest radiotherapy in combination with oral vinorelbine (Navelbine) …
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CLINICAL_TRIALS trial_result · 2014-02-11Clinical Trial Update: Once Weekly Radiation for Lung Cancer With Chemotherapy [NA]
This entry reports the completion of a clinical trial evaluating once-weekly radiation in combination with chemotherapy for non-small cell l…
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CLINICAL_TRIALS trial_result · 2014-02-10Clinical Trial Update: Safety Study of Individual Paclitaxel Dose Adjustment Based on Pharmacokinetics in Non-Small Cell Lung Cancer (NSCLC) [Phase 3]
Phase 3 safety study evaluating individual paclitaxel dose adjustment based on pharmacokinetics in non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2014-02-04Clinical Trial Update: Bevacizumab, Docetaxel, and Gemcitabine Patients With Stage IIIB, Stage IV, or Recurrent Non-Small Cell Lung Cancer [Phase 2]
Phase 2 clinical trial assessing bevacizumab with docetaxel and gemcitabine in stage IIIB, stage IV, or recurrent non-small cell lung cancer…
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CLINICAL_TRIALS trial_result · 2014-01-30Clinical Trial Update: Pulsed Paclitaxel And Daily Thoracic Radiotherapy For Inoperable (Stage I/II) Or Unresectable Lung Cancer [Phase 1, Phase 2]
Phase 1/2 trial evaluating pulsed paclitaxel in combination with daily thoracic radiotherapy for inoperable or unresectable non-small cell l…
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CLINICAL_TRIALS trial_result · 2014-01-29Clinical Trial Update: A Pilot Phase 2 Trial of the Immunogenicity, and Safety of GI-4000; an Inactivated Recombinant S. Cerevisiae Expressing Mutant Ras Protein, as Consolidation Therapy Following Curative Treatment for Stage I-III Non-Small Cell Lung Cancer (NSCLC) With Tumor Sequence Confirmation of K-ras Mutation [Phase 2]
A pilot Phase 2 trial evaluated GI-4000, an inactivated recombinant yeast expressing mutant Ras, as consolidation therapy after curative tre…
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CLINICAL_TRIALS withdrawal · 2014-01-29Clinical Trial Update: Hypo-Hyperfractionated Chest Radiation for Non Small Cell Lung Cancer With Taxotere/Xeloda Combination Chemotherapy [Phase 1, Phase 2]
A clinical trial update indicates that the phase 1/2 study evaluating hypo-hyperfractionated chest radiation with Taxotere and Xeloda for no…
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CLINICAL_TRIALS trial_result · 2014-01-24Clinical Trial Update: Positron Emission Tomography Scan and CT Scan in Planning Radiation Therapy for Patients With Stage II or Stage III Non-Small Cell Lung Cancer [NA]
This clinical trial update describes using positron emission tomography (PET) and CT scans to plan radiation therapy for patients with stage…
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CLINICAL_TRIALS research · 2014-01-22Clinical Trial Update: Establishment and Characterization of Patient-Derived Non-Small Cell Lung Cancer Xenografts and Cell Cultures
Establishment and characterization of patient-derived non-small cell lung cancer xenografts and cell cultures using patient tumor samples.
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CLINICAL_TRIALS trial_result · 2014-01-22Clinical Trial Update: Customizing First Line Chemotherapy in Advanced Non-Small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial on customizing first-line chemotherapy for advanced non-small cell lung cancer has been terminated. The study was s…
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EMA withdrawal · 2014-01-21EMA Lapsed: Docetaxel Teva Pharma (docetaxel) — Teva Pharma B.V.
The EMA lists Docetaxel Teva Pharma as lapsed (withdrawn) for multiple indications including non-small cell lung carcinoma, breast neoplasms…
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CLINICAL_TRIALS trial_result · 2014-01-20Clinical Trial Update: Oral HYCAMTIN Plus Whole Brain Radiation Therapy In Treatment Of Brain Metastases Resulting From Non-Small Lung Cancer [Phase 3]
Phase 3 trial evaluating oral topotecan (HYCAMTIN) in combination with whole-brain radiation therapy for brain metastases from non-small cel…
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CLINICAL_TRIALS trial_result · 2014-01-17Clinical Trial Update: Dose Escalation Study of RAD001 in Combination w/Chemotherapy & Radiation in Patients With NSCLC [Phase 1]
A Phase 1 dose-escalation study of RAD001 (everolimus) in combination with chemotherapy and radiation for non-small cell lung cancer was ter…
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CLINICAL_TRIALS trial_result · 2014-01-16Clinical Trial Update: Safety and Exploratory Efficacy of Kanglaite Injection in Non Small Cell Lung Cancer [Phase 2]
The update reports safety data and exploratory efficacy signals from a Phase 2 trial of Kanglaite Injection in Stage IV non-small cell lung …
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CLINICAL_TRIALS trial_result · 2014-01-16Clinical Trial Update: Two Regimens of Docetaxel in Treating Patients Who Have Not Received Chemotherapy For Unresectable Stage IIIB or Stage IV Non-Small Cell Lung Cancer [Phase 2]
Phase 2 clinical trial evaluating two regimens of docetaxel in chemotherapy-naive patients with unresectable stage IIIB or stage IV non-smal…
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CLINICAL_TRIALS trial_result · 2014-01-16Clinical Trial Update: Safety Study: Combined Modality Treatment for Non-Small Cell Lung Cancer [Phase 1]
Phase 1 safety trial of a combined modality treatment for non-small cell lung cancer was terminated.
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CLINICAL_TRIALS withdrawal · 2014-01-16Clinical Trial Update: Changes in Brain Structure Related to Systemic Chemotherapy Treatment: A Prospective Study in Individuals Diagnosed With Non-small Cell Lung Cancer Utilizing High-resolution Structural Magnetic Resonance Imaging
The clinical trial investigating brain structure changes in non-small cell lung cancer patients treated with systemic chemotherapy was termi…