Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2014-12-02Clinical Trial Update: Phase II Study of Gefitinib Plus Nimotuzumab Versus Gefitinib in Non-small Cell Lung Cancer [Phase 2]
This document reports a completed Phase II trial comparing Gefitinib plus Nimotuzumab versus Gefitinib alone in patients with Non-Small Cell…
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CLINICAL_TRIALS research · 2014-12-02Clinical Trial Update: Identification of EGFR-TKIs Sensitivity or Resistance Markers in NSCLC May Help in Optimal Patient Selection
This clinical trial update discusses efforts to identify biomarkers predicting sensitivity or resistance to EGFR-TKIs in non-small cell lung…
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CLINICAL_TRIALS trial_result · 2014-12-01Clinical Trial Update: LUME-Lung 1: BIBF 1120 Plus Docetaxel as Compared to Placebo Plus Docetaxel in 2nd Line Non Small Cell Lung Cancer [Phase 3]
A Phase 3 trial (LUME-Lung 1) evaluating BIBF 1120 (nintedanib) plus docetaxel vs placebo plus docetaxel in second-line non-small cell lung …
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CLINICAL_TRIALS trial_result · 2014-11-25Clinical Trial Update: Customized Neoadjuvant Versus Standard Chemotherapy in NSCL Patients With Resectable Stage IIIA (N2)Disease [Phase 2]
A Phase 2 clinical trial comparing customized neoadjuvant chemotherapy versus standard chemotherapy in patients with resectable stage IIIA (…
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CLINICAL_TRIALS trial_result · 2014-11-24Clinical Trial Update: Study of Everolimus, Pemetrexed, Carboplatin, and Bevacizumab to Treat Stage IV Lung Cancer [Phase 1]
Phase 1 study evaluating a four-drug combination of everolimus, pemetrexed, carboplatin, and bevacizumab for stage IV non-small cell lung ca…
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CLINICAL_TRIALS trial_result · 2014-11-21Clinical Trial Update: LUX-Lung 8: A Phase III Trial of Afatinib (BIBW 2992) Versus Erlotinib for the Treatment of Squamous Cell Lung Cancer After at Least One Prior Platinum Based Chemotherapy [Phase 3]
Phase III trial comparing afatinib versus erlotinib in squamous cell non-small cell lung cancer after platinum-based therapy; results comple…
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CLINICAL_TRIALS trial_result · 2014-11-21Clinical Trial Update: Amifostine in Treating Patients With Stage II or Stage III Non-small Cell Lung Cancer [Phase 3]
This clinical trial update reports the completion of a Phase 3 study evaluating amifostine in patients with Stage II/III non-small cell lung…
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CLINICAL_TRIALS trial_result · 2014-11-21Clinical Trial Update: Clinicopathological Features of NSCLC Patients Associated With the Chromosome 2p (EML4-ALK)
Completed clinical trial investigating clinicopathological features of non-small cell lung cancer patients associated with the EML4-ALK chro…
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CLINICAL_TRIALS trial_result · 2014-11-20Clinical Trial Update: Lume Lung 2 : BIBF 1120 Plus Pemetrexed Compared to Placebo Plus Pemetrexed in 2nd Line Nonsquamous NSCLC [Phase 3]
Phase 3 LUME-Lung 2 trial comparing nintedanib (BIBF-1120) plus pemetrexed versus placebo plus pemetrexed in second-line non-squamous non-sm…
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CLINICAL_TRIALS trial_result · 2014-11-20Clinical Trial Update: BIBF 1120 in Combination With Pemetrexed in Advanced Non Small Cell Lung Cancer (NSCLC) [Phase 1]
Phase 1 trial of BIBF 1120 (nintedanib) in combination with pemetrexed for advanced non-small cell lung cancer was terminated; results were …
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CLINICAL_TRIALS trial_result · 2014-11-19Clinical Trial Update: A Study of Avastin (Bevacizumab) in Patients With Non-Squamous Non-Small Cell Lung Cancer With Asymptomatic Untreated Brain Metastasis [Phase 2]
Phase 2 study evaluating Avastin (bevacizumab) in patients with non-squamous non-small cell lung cancer and asymptomatic untreated brain met…
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CLINICAL_TRIALS research · 2014-11-18Clinical Trial Update: Retrospective Study in Non Small Cell Lung Cancer (NSCLC) With Epidermal Growth Factor Receptor (EGFR)
A completed retrospective study in non-small cell lung cancer focusing on EGFR-related aspects is reported in this clinical trial update.
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CLINICAL_TRIALS withdrawal · 2014-11-17Clinical Trial Update: Combination of gp96-Ig Vaccine, Theophylline and Oxygen for the Treatment of Patients With Advanced, Relapsed or Metastatic Non-Small Cell Lung Cancer [Phase 1]
A Phase 1 trial combining gp96-Ig vaccine, theophylline, and oxygen for advanced, relapsed or metastatic non-small cell lung cancer has been…
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CLINICAL_TRIALS trial_result · 2014-11-13Clinical Trial Update: Phase 1b/2 Study of Retaspimycin HCl (IPI-504) in Combination With Everolimus in KRAS Mutant Non-small Cell Lung Cancer [Phase 1, Phase 2]
A completed Phase 1b/2 study evaluating the combination of retaspimycin HCl (IPI-504) and everolimus in KRAS-mutant non-small cell lung canc…
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CLINICAL_TRIALS withdrawal · 2014-11-13Clinical Trial Update: A Proof of Principle Study of Aminolevulinic Acid (ALA) - Induced Fluorescence Detection in Resectable Non-Small Cell Lung Cancer [Phase 1]
A Phase 1 proof-of-principle trial investigating aminolevulinic acid–induced fluorescence for detecting resectable non-small cell lung cance…
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CLINICAL_TRIALS trial_result · 2014-11-11Clinical Trial Update: A Study of Tarceva (Erlotinib) in Combination With Avastin (Bevacizumab) in Patients With Advanced Non-Small Cell Lung Cancer. [Phase 2]
This is a Phase 2 trial evaluating Tarceva (erlotinib) in combination with Avastin (bevacizumab) for advanced non-small cell lung cancer; re…
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CLINICAL_TRIALS trial_result · 2014-11-11Clinical Trial Update: Cyclophosphamide or Denileukin Diftitox Followed By Expanding a Patient's Own T Cells in the Laboratory in Treating Patients With HER-2/Neu Overexpressing Metastatic Breast Cancer, Ovarian Cancer, or Non-Small Cell Lung Cancer Previously Treated With HER-2/Neu Vaccine [Phase 1]
Phase 1 study evaluating conditioning with cyclophosphamide or denileukin diftitox followed by expansion of the patient’s own T cells for HE…
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CLINICAL_TRIALS research · 2014-11-11Clinical Trial Update: Comparison of Different Types of Surgery in Treating Patients With Early-stage Non-small Cell Lung Cancer
The clinical trial update describes a trial comparing different surgical approaches for early-stage non-small cell lung cancer, including st…
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CLINICAL_TRIALS trial_result · 2014-11-10Clinical Trial Update: Second Line Erlotinib (Tarceva) Plus Digoxin in Non-Small Cell Lung Cancer [Phase 2]
This document reports results from a Phase 2 trial of second-line erlotinib plus digoxin in non-small cell lung cancer. The study was termin…
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CLINICAL_TRIALS trial_result · 2014-11-07Clinical Trial Update: MK-0646 Insulin Growth Factor 1 Receptor Antibody in Stage IIIb or IV Metastatic Non-Squamous Lung Cancer [Phase 2]
Phase 2 trial of MK-0646 (dalotuzumab), an IGF-1 receptor antibody, in stage IIIb/IV metastatic non-squamous non-small cell lung cancer has …
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CLINICAL_TRIALS trial_result · 2014-11-05Clinical Trial Update: Icotinib as the Adjunctive Treatment After Surgery in Stage I-IIIB Lung Adenocarcinoma Patients With EGFR Gene Mutation [Phase 4]
A Phase 4 clinical trial evaluating icotinib as adjuvant therapy after surgery for EGFR-mutant stage I-IIIB non-small cell lung cancer (lung…
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FDA approval · 2014-11-05FDA Approved: DOCETAXEL — Original Application (Dr. Reddy's Laboratories Inc.)
FDA approves the original (ANDA) application for docetaxel generic produced by Dr. Reddy's Laboratories.
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CLINICAL_TRIALS research · 2014-11-05Clinical Trial Update: Value of Physical Capacity Tests in Lung Cancer
A completed clinical trial evaluating the value of physical capacity tests in patients with lung cancer (non-small cell and small cell).
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CLINICAL_TRIALS trial_result · 2014-11-04Clinical Trial Update: EGF Ointment for Erlotinib Skin Lesion [Phase 2]
Phase 2 study updates the use of epidermal growth factor ointment to manage erlotinib-induced skin lesions in patients with non-small cell l…
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CLINICAL_TRIALS trial_result · 2014-11-04Clinical Trial Update: Radiation Therapy in Treating Patients With Stage I Non-Small Cell Lung Cancer [Phase 2]
Phase 2 trial update on radiation therapy for patients with stage I non-small cell lung cancer.