Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-09-17Clinical Trial Update: Surgery, Gemcitabine, Cisplatin, and Radiation Therapy in Treating Patients With Stage II or Stage III Non-Small Cell Lung Cancer [Phase 2]
A Phase 2 trial evaluating surgery with gemcitabine, cisplatin, and radiation for stage II or III non-small cell lung cancer was terminated,…
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CLINICAL_TRIALS withdrawal · 2015-09-16Clinical Trial Update: Stereotactic Radiosurgery Followed by Wedge Resection in Treating Patients With Early Stage Peripheral Non-small Cell Lung Cancer [NA]
A clinical trial evaluating stereotactic radiosurgery followed by wedge resection for early-stage peripheral non-small cell lung cancer has …
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CLINICAL_TRIALS research · 2015-09-15Clinical Trial Update: Nimotuzumab in Combination With Radiochemotherapy for Patients With Stage IIIA/IIIB Non-small Cell Lung Cancer [NA]
A clinical trial update describes nimotuzumab in combination with radiochemotherapy for stage IIIA/IIIB non-small cell lung cancer, with the…
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CLINICAL_TRIALS trial_result · 2015-09-14Clinical Trial Update: S0536: Cetuximab, Paclitaxel, Carboplatin, and Bevacizumab in Treating Patients With Advanced Non-Small Cell Lung Cancer [Phase 2]
This Phase 2 clinical trial (S0536) evaluated the combination of cetuximab, paclitaxel, carboplatin, and bevacizumab in patients with advanc…
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FDA approval · 2015-09-14FDA Approved: XALKORI — Supplemental Application (Pfizer Laboratories Div Pfizer Inc)
FDA approved a supplemental application for XALKORI (crizotinib) from Pfizer, expanding regulatory authorization for the drug.
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CLINICAL_TRIALS research · 2015-09-09Clinical Trial Update: Icotinib in Combination With Chemotherapy Versus Chemotherapy Alone in Patients Progressed After Icotinib Treatment [Phase 2]
Phase 2 trial evaluating icotinib in combination with chemotherapy versus chemotherapy alone in patients with non-small cell lung cancer who…
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CLINICAL_TRIALS research · 2015-09-09Clinical Trial Update: First-line Treatment With Icotinib in Elder NSCLC EGFR Mutated Patients [Phase 4]
This document provides a Phase 4 clinical trial update on first-line icotinib therapy in elderly patients with EGFR-mutated non-small cell l…
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CLINICAL_TRIALS trial_result · 2015-09-07Clinical Trial Update: MONET1-MOtesanib NSCLC Efficacy and Tolerability Study [Phase 3]
The MONET1-Motesanib NSCLC Phase 3 trial was terminated, with the update noting the status but not providing results.
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CLINICAL_TRIALS trial_result · 2015-09-07Clinical Trial Update: Trial of Bevacizumab and Ixabepilone for Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) [Phase 2]
Phase 2 trial of bevacizumab and ixabepilone in advanced or metastatic non-small cell lung cancer has been terminated.
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CLINICAL_TRIALS trial_result · 2015-09-04Clinical Trial Update: Study of Apatinib in RET Fusion Positive Advanced Non-small Cell Lung Cancer [Phase 2]
Update on a Phase 2 study of Apatinib in RET fusion-positive advanced non-small cell lung cancer; current status is UNKNOWN.
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CLINICAL_TRIALS research · 2015-09-02Clinical Trial Update: A Open-label Prospective Cohort Trial of Curcumin Plus Tyrosine Kinase Inhibitors (TKI) for EGFR -Mutant Advanced NSCLC [Phase 1]
Open-label Phase 1 cohort study evaluating curcumin in combination with tyrosine kinase inhibitors for patients with EGFR-mutant advanced no…
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CLINICAL_TRIALS withdrawal · 2015-09-02Clinical Trial Update: A Study Of Ranpirnase(Onconase®) To Pemetrexed Plus Carboplatin In Patients With Non-Squamous Non-Small Cell Lung Cancer [Phase 2]
A Phase 2 study evaluating ranpirnase (Onconase) in combination with pemetrexed and carboplatin for non-squamous non-small cell lung cancer …
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CLINICAL_TRIALS trial_result · 2015-08-28Clinical Trial Update: Efficacy and Safety of Pyrotinib in Patients With HER2 Mutation Advanced Non-Small Cell Lung Cancer [Phase 2]
Phase 2 trial evaluating the efficacy and safety of pyrotinib in patients with HER2-mutant advanced non-small cell lung cancer.
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FDA approval · 2015-08-28FDA Approved: ERLOTINIB — Original Application (Teva Pharmaceuticals USA, Inc.)
FDA approves Teva's erlotinib original application, making a generic version available for the same uses as the reference product. The appro…
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CLINICAL_TRIALS trial_result · 2015-08-27Clinical Trial Update: Nimotuzumab Plus Docetaxel in Chemotherapy-Refractory/Resistant Patients With Advanced Non-Small-Cell Lung Cancer [Phase 2]
A Phase 2 trial evaluating nimotuzumab in combination with docetaxel for advanced non-small cell lung cancer has been terminated.
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CLINICAL_TRIALS withdrawal · 2015-08-27Clinical Trial Update: Study of Lonafarnib in Combination With Paclitaxel and Carboplatin in Patients With Non-Small Cell Lung Cancer (Study P01901)(TERMINATED) [Phase 3]
A Phase 3 trial evaluating lonafarnib with paclitaxel and carboplatin in non-small cell lung cancer has been terminated.
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CLINICAL_TRIALS trial_result · 2015-08-25Clinical Trial Update: Inositol in Preventing Lung Cancer in Current or Former Smokers With Bronchial Dysplasia [Phase 2]
Phase II trial evaluating whether inositol can prevent lung cancer in current or former smokers with bronchial dysplasia; the study is compl…
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CLINICAL_TRIALS trial_result · 2015-08-21Clinical Trial Update: A Randomized Trial Of PF-00299804 Taken Orally Versus Erlotinib Taken Orally For Treatment Of Advanced Non-Small Cell Lung Cancer That Has Progressed After One Or Two Prior Chemotherapy Regimen [Phase 2]
A Phase 2 randomized trial comparing Pfizer's PF-00299804 (dacomitinib) to erlotinib in advanced non-small cell lung cancer that progressed …
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CLINICAL_TRIALS trial_result · 2015-08-20Clinical Trial Update: Dose-Finding Study of Cabozantinib (XL184) in Japanese Subjects With Advanced Cancer [Phase 1]
A Phase 1 dose-finding study of cabozantinib (XL184) in Japanese subjects with advanced cancer has been completed.
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CLINICAL_TRIALS research · 2015-08-20Clinical Trial Update: Expression and Sequence of Calcium Channels in Non-small Cell Lung Carcinoma (NSCLC)
A clinical trial update investigating the expression and genetic sequence of calcium channels in non-small cell lung cancer.
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CLINICAL_TRIALS withdrawal · 2015-08-20Clinical Trial Update: Safety Study of XL647 and XL147 Administered in Combination Daily in Adults With Solid Tumors [Phase 1]
Phase 1 safety study of daily combination therapy with XL647 and XL147 in adults with solid tumors; the study has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2015-08-19Clinical Trial Update: Nimotuzumab in Combination With Cisplatin and Docetaxel for Patients With Advanced Non-small Cell Lung Cancer [Phase 1]
A Phase 1 clinical trial of nimotuzumab with cisplatin and docetaxel for advanced non-small cell lung cancer has been withdrawn.
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CLINICAL_TRIALS trial_result · 2015-08-18Clinical Trial Update: ARQ 197 Plus Erlotinib in Patient With Locally Advanced or Metastatic EGFR Mutation-positive Non-small-cell Lung Cancer [Phase 2]
Phase 2 trial evaluating the combination of tivantinib (ARQ-197) and erlotinib in locally advanced or metastatic EGFR mutation-positive non-…
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CLINICAL_TRIALS trial_result · 2015-08-18Clinical Trial Update: IDO Peptid Vaccination for Stage III-IV Non Small-cell Lung Cancer Patients. [Phase 1]
This update notes the completion of a Phase 1 study evaluating an IDO peptide vaccination in patients with stage III-IV non-small cell lung …
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CLINICAL_TRIALS trial_result · 2015-08-18Clinical Trial Update: Safety Study of Tecemotide (L-BLP25) in Non-Small Cell Lung Cancer (NSCLC) Subjects With Unresectable Stage III Disease [Phase 2]
Phase 2 safety study of Tecemotide (L-BLP25) in patients with unresectable Stage III non-small cell lung cancer has completed, with results …