Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2015-12-15Clinical Trial Update: Concurrent Nab-P/Carboplatin and Thoracic Radiotherapy in Squamous Cell Lung Cancer [Phase 2]
Phase 2 clinical trial update evaluating concurrent nab-paclitaxel and carboplatin with thoracic radiotherapy in squamous cell non-small cel…
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CLINICAL_TRIALS withdrawal · 2015-12-14Clinical Trial Update: Study of Motesanib (AMG 706) in Combination With Paclitaxel and Carboplatin for Advanced Non-Squamous Non-Small Cell Lung Cancer [Phase 3]
A Phase 3 study evaluating motesanib in combination with paclitaxel and carboplatin for advanced non-squamous non-small cell lung cancer has…
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CLINICAL_TRIALS trial_result · 2015-12-14Clinical Trial Update: A Study of Tarceva (Erlotinib) or Placebo in Combination With Platinum-Based Therapy as First Line Treatment in Patients With Advanced or Recurrent Non-Small Cell Lung Cancer [Phase 3]
A Phase 3 trial evaluating Tarceva (erlotinib) in combination with platinum-based therapy versus placebo with platinum in first-line advance…
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CLINICAL_TRIALS trial_result · 2015-12-14Clinical Trial Update: GRN1005 in Non-Small Cell Lung Cancer (NSCLC) Patients With Brain Metastases (GRABM-L) [Phase 2]
GRN1005 was studied in a Phase 2 trial (GRABM-L) for non-small cell lung cancer with brain metastases. The study is terminated and results h…
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FDA approval · 2015-12-11FDA Approved: ALECENSA — Original Application (Genentech, Inc.)
FDA approved ALECENSA (alectinib hydrochloride) from Genentech under NDA208434 as an original application for the treatment of ALK-positive …
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CLINICAL_TRIALS trial_result · 2015-12-09Clinical Trial Update: Afatinib vs Erlotinib as 2nd TKI After Failure to 1st TKI and Chemotherapy for Metastatic NSCLC [Phase 2]
A Phase 2 trial compares afatinib versus erlotinib as second TKI therapy after failure of a first TKI and chemotherapy in metastatic non-sma…
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CLINICAL_TRIALS trial_result · 2015-12-09Clinical Trial Update: Phase 1b/2 Study of Carfilzomib in Relapsed Solid Tumors, Multiple Myeloma, or Lymphoma [Phase 1, Phase 2]
ClinicalTrials.gov reports a Phase 1b/2 study of carfilzomib in relapsed solid tumors, multiple myeloma, or lymphoma. The study is completed…
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CLINICAL_TRIALS research · 2015-12-09Clinical Trial Update: Explore the Individual Treatment of Docetaxel and Paclitaxel in NSCLC, NPC and BRC by PK-guided Dosing Strategy [NA]
A clinical trial update examining pharmacokinetic-guided dosing of docetaxel and paclitaxel in non-small cell lung cancer, nasopharyngeal ca…
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CLINICAL_TRIALS trial_result · 2015-12-03Clinical Trial Update: DNP-Modified Autologous Tumor Cell Vaccine for Resectable Non-Small Cell Lung Cancer [Phase 1, Phase 2]
A Phase 1/2 trial of AVAX's DNP-modified autologous tumor cell vaccine for completely resectable non-small cell lung cancer was terminated.
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CLINICAL_TRIALS trial_result · 2015-12-02Clinical Trial Update: Phase 2 Study of REOLYSIN® in Combination With Paclitaxel and Carboplatin for Non-Small Cell Lung Cancer With KRAS or EGFR Activation [Phase 2]
Phase 2 study evaluating REOLYSIN in combination with paclitaxel and carboplatin for non-small cell lung cancer with KRAS or EGFR activation…
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CLINICAL_TRIALS trial_result · 2015-11-26Clinical Trial Update: Chemotherapy and Radiation in Treating Participants With Stage 3 Non-Small Cell Lung Cancer [Phase 3]
This clinical trial update reports the results of a Phase 3 study evaluating chemotherapy and radiation in participants with stage 3 non-sma…
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CLINICAL_TRIALS trial_result · 2015-11-20Clinical Trial Update: Cancer Vaccine Study for Unresectable Stage III Non-small Cell Lung Cancer (START) [Phase 3]
A Phase 3 trial (START) evaluating the belagenpumatucel-L cancer vaccine in unresectable stage III non-small cell lung cancer has completed.…
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CLINICAL_TRIALS trial_result · 2015-11-20Clinical Trial Update: Docetaxel (Taxotere), Vinorelbine, and Bevacizumab, as Adjuvant Chemotherapy for Patients With Resected Stage I-III Non-small Cell Lung Cancer [NA]
This clinical trial update reports results for an adjuvant triple-drug regimen (docetaxel, vinorelbine, and bevacizumab) in patients with re…
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CLINICAL_TRIALS trial_result · 2015-11-20Clinical Trial Update: Erlotinib and AT-101 in Advanced Non-Small Cell Lung Cancer (NSCLC) Patients With Epidermal Growth Factor Receptor (EGFR) Activating Mutations [Phase 2]
A phase 2 trial evaluating the combination of erlotinib and AT-101 in advanced non-small cell lung cancer with EGFR activating mutations was…
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CLINICAL_TRIALS trial_result · 2015-11-20Clinical Trial Update: Erlotinib and Chemotherapy for Patients With Stage IB-IIIA NSCLC With EGFR Mutations (ECON) [Phase 2]
Phase 2 trial evaluating erlotinib in combination with chemotherapy for stage IB-IIIA non-small cell lung cancer with EGFR mutations has com…
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CLINICAL_TRIALS research · 2015-11-20Clinical Trial Update: Cisplatin for Malignant Pleural Effusion in Patients With Non-small-cell Lung Cancer [NA]
A clinical trial update evaluating cisplatin for malignant pleural effusion in patients with non-small cell lung cancer. The current study s…
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CLINICAL_TRIALS withdrawal · 2015-11-20Clinical Trial Update: Feasibility of Mutational Analysis of Non-Small Cell Lung Cancer (NSCLC) Using Low-volume Lung Aspirates
The trial evaluating mutational analysis of non-small cell lung cancer using low-volume lung aspirates has been withdrawn.
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CLINICAL_TRIALS research · 2015-11-20Clinical Trial Update: A Non-interventional Study (NIS) Registry for the Epidemiological and Scientific Evaluation of Epidermal Growth Factor Receptor (EGFR) Mutation Status in Patients With Newly Diagnosed Locally Advanced or Metastatic Non Small Cell Lung Cancer (NSCLC) (Stage IIIB/IV Non-small Cell Lung Cancer).
A completed non-interventional registry study evaluating EGFR mutation status in newly diagnosed locally advanced or metastatic non-small ce…
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CLINICAL_TRIALS trial_result · 2015-11-20Clinical Trial Update: Predictive Value of FDG PET/CT, DWI and DCE-MRI Scans for Non-small Cell Lung Cancer Patients Receiving Chemotherapy
A completed clinical trial evaluating imaging biomarkers (FDG PET/CT, diffusion-weighted MRI, and dynamic contrast-enhanced MRI) as predicto…
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CLINICAL_TRIALS trial_result · 2015-11-18Clinical Trial Update: Phase 2b Randomized Controlled Study of Tecemotide (L-BLP25) for Immunotherapy of NSCLC (Non-Small Cell Lung Cancer) [Phase 2]
Phase 2b randomized trial of Tecemotide (L-BLP25) for non-small cell lung cancer completed; results were posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-11-18Clinical Trial Update: RO4929097 in Treating Patients With Advanced Non-Small Cell Lung Cancer Who Have Recently Completed Treatment With Front-Line Chemotherapy [Phase 2]
Phase 2 trial of RO4929097 in advanced non-small cell lung cancer patients recently treated with front-line chemotherapy; the study was term…
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CLINICAL_TRIALS trial_result · 2015-11-17Clinical Trial Update: Cetuximab, Paclitaxel, Carboplatin, and Radiation Therapy in Treating Patients With Unresectable Stage IIIA or Stage IIIB Non-Small Cell Lung Cancer [Phase 2]
A completed Phase 2 trial evaluating a combination of cetuximab, paclitaxel, carboplatin, and radiation therapy in patients with unresectabl…
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CLINICAL_TRIALS trial_result · 2015-11-17Clinical Trial Update: Chemotherapy Plus Radiation Therapy With or Without Surgery in Treating Patients With Stage IIIA Non-small Cell Lung Cancer [Phase 3]
Phase 3 trial evaluating chemotherapy plus radiation therapy with or without surgery for Stage IIIA non-small cell lung cancer. The study st…
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CLINICAL_TRIALS trial_result · 2015-11-17Clinical Trial Update: Gemcitabine, Carboplatin or Paclitaxel Plus Radiation Therapy in Treating Patients With Stage IIIA or IIIB Non-Small Cell Lung Cancer [Phase 1]
This completed Phase 1 clinical trial evaluated adding gemcitabine with either carboplatin or paclitaxel plus radiation therapy in patients …
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CLINICAL_TRIALS trial_result · 2015-11-16Clinical Trial Update: A Study of Erlotinib [Tarceva] as Monotherapy or Intermittent Dosing With Docetaxel in Patients With Advanced or Metastatic Non-Small Cell Lung Cancer. (TALISMAN) [Phase 2]
Phase 2 trial evaluating erlotinib as monotherapy or intermittent dosing with docetaxel in advanced or metastatic non-small cell lung cancer…