Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2016-06-24Clinical Trial Update: Personalized Adaptive Radiation Therapy With Individualized Systemic Targeted Therapy (PARTIST) for Locally Advanced, Non-small Cell Lung Cancer With Genomic Driver Mutations [EARLY_Phase 1]
The PARTIST trial evaluating personalized adaptive radiation therapy with individualized systemic targeted therapy for locally advanced non-…
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CLINICAL_TRIALS trial_result · 2016-06-23Clinical Trial Update: Phase 3 Trial in Squamous Non Small Cell Lung Cancer Subjects Comparing Ipilimumab Versus Placebo in Addition to Paclitaxel and Carboplatin [Phase 3]
Phase 3 trial evaluating ipilimumab plus paclitaxel and carboplatin versus placebo in squamous non-small cell lung cancer; study completed w…
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CLINICAL_TRIALS trial_result · 2016-06-23Clinical Trial Update: Iressa Follow-up Trial [Phase 3]
Phase 3 follow-up trial of Iressa (gefitinib) in non-small cell lung cancer and breast cancer has completed, with results posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-06-22Clinical Trial Update: Study to Assess the Effect of AZD9291 on the Blood Levels of Simvastatin in Patients With EGFRm+ NSCLC [Phase 1]
This Phase 1 trial assessed whether AZD9291 (osimertinib) alters the blood levels of simvastatin in patients with EGFR mutation-positive non…
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CLINICAL_TRIALS trial_result · 2016-06-22Clinical Trial Update: Docetaxel With or Without Low-dose, Short Course Sunitinib in Refractory Solid Tumors [Phase 2]
Phase 2 trial update evaluating docetaxel with or without low-dose, short-course sunitinib in refractory solid tumors, including breast canc…
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CLINICAL_TRIALS research · 2016-06-21Clinical Trial Update: Acquired Resistant Mechanism of the First-generation EGFR TKIs
This clinical trial update discusses the acquired resistance mechanisms to first-generation EGFR tyrosine kinase inhibitors in non-small cel…
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CLINICAL_TRIALS research · 2016-06-17Clinical Trial Update: A Multi-center Prospective Observational Biomarker Study on EGFRm+ Non-small Cell Lung Cancer Patients With Leptomeningeal Metastasis
A multi-center prospective observational biomarker study in EGFR-mutant non-small cell lung cancer patients with leptomeningeal metastasis.
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CLINICAL_TRIALS trial_result · 2016-06-16Clinical Trial Update: Pemetrexed Plus Cisplatin Versus Gemcitabine Plus Cisplatin for Advanced NSCLC Metastatic Non-small Cell Lung Cancer [Phase 2]
A Phase 2 randomized trial compared pemetrexed plus cisplatin versus gemcitabine plus cisplatin in advanced/metastatic non-small cell lung c…
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CLINICAL_TRIALS trial_result · 2016-06-14Clinical Trial Update: A Study of AMG 951 [rhApo2L/TRAIL] in Subjects With Previously Untreated Non-Small Cell Lung Cancer (NSCLC) Treated With Chemotherapy +/- Bevacizumab [Phase 2]
A Phase 2 clinical trial evaluating AMG 951 (rhApo2L/TRAIL) in previously untreated non-small cell lung cancer patients treated with chemoth…
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CLINICAL_TRIALS trial_result · 2016-06-14Clinical Trial Update: A Placebo Controlled Study Comparing AZD1775+ Docetaxel Versus Placebo+Docetaxel to Treat Lung Cancer [Phase 2]
A Phase 2 randomized trial comparing AZD1775 plus docetaxel versus placebo plus docetaxel in previously treated non-small cell lung cancer w…
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CLINICAL_TRIALS research · 2016-06-10Clinical Trial Update: Identification of Marker of Primary or Acquired Resistance to Anti Tumorous Treatment [NA]
An ongoing clinical trial is exploring markers of primary or acquired resistance to anticancer therapies in melanoma and lung cancers; curre…
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CLINICAL_TRIALS trial_result · 2016-06-09Clinical Trial Update: An Investigational Drug, PF-02341066, Is Being Studied In Patients With Advanced Non-Small Cell Lung Cancer With A Specific Gene Profile Involving The Anaplastic Lymphoma Kinase (ALK) Gene [Phase 2]
A Phase 2 clinical trial evaluating PF-02341066 (crizotinib) in patients with advanced non-small cell lung cancer with ALK gene alterations …
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CLINICAL_TRIALS trial_result · 2016-06-09Clinical Trial Update: Tolerability and Efficacy of Tremelimumab in Combination With Gefitinib in NSCLC Patients [Phase 1]
This Phase 1 trial update reports tolerability and early efficacy data for the combination of tremelimumab with gefitinib in non-small cell …
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CLINICAL_TRIALS trial_result · 2016-06-07Clinical Trial Update: Phase II AZD9291 Open Label Study in NSCLC After Previous EGFR TKI Therapy in EGFR and T790M Mutation Positive Tumours [Phase 2]
Phase II open-label study of AZD9291 (osimertinib) in EGFR-mutant, T790M-positive non-small cell lung cancer after progression on prior EGFR…
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CLINICAL_TRIALS trial_result · 2016-06-06Clinical Trial Update: Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Carboplatin in Treating Patients With Stage IIIB, Stage IV, or Recurrent Non-Small Cell Lung Cancer [Phase 2]
Phase 2 trial evaluating nab-paclitaxel in combination with carboplatin for stage IIIB/IV or recurrent non-small cell lung cancer has comple…
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CLINICAL_TRIALS trial_result · 2016-06-03Clinical Trial Update: Phase 1b/2 Trial of AMG386 With Pemetrexed and Carboplatin in Non-Small Cell Lung Cancer [Phase 1, Phase 2]
Phase 1b/2 trial update of AMG-386 with pemetrexed and carboplatin in non-small cell lung cancer has completed the indicated phases.
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CLINICAL_TRIALS research · 2016-06-03Clinical Trial Update: Individualized Adaptive Radiotherapy Based on PET/CT and IMRT for Locally Advanced Non-Small Cell Lung Cancer (NSCLC) [Phase 3]
This entry describes a Phase 3 clinical trial evaluating individualized adaptive radiotherapy guided by PET/CT and IMRT for locally advanced…
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CLINICAL_TRIALS trial_result · 2016-06-02Clinical Trial Update: Iressa v BSC (Best Supportive Care) in First Line NSCLC [Phase 2, Phase 3]
Phase 2 and Phase 3 trials comparing Iressa (gefitinib) to Best Supportive Care in first-line non-small cell lung cancer have been completed…
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CLINICAL_TRIALS trial_result · 2016-06-02Clinical Trial Update: Pemetrexed Plus Cetuximab in Patients With Recurrent Non Small Cell Lung Cancer [Phase 1, Phase 2]
The update reports the completion of a Phase 1/2 study evaluating the combination of pemetrexed with cetuximab in patients with recurrent no…
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CLINICAL_TRIALS research · 2016-06-02Clinical Trial Update: A Study of Hypofractionated Radiotherapy for Limited Metastatic NSCLC Harboring Sensitizing EGFR Mutations After First Line TKI Therapy [Phase 2]
A Phase 2 clinical trial update evaluating hypofractionated radiotherapy for limited metastatic non-small cell lung cancer with EGFR-sensiti…
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CLINICAL_TRIALS trial_result · 2016-06-01Clinical Trial Update: Dacomitinib (PF-00299804) As A Single Oral Agent In Selected Patients With Adenocarcinoma Of The Lung [Phase 2]
Phase 2 clinical trial updating Dacomitinib (PF-00299804) as a single oral agent in selected patients with non-small cell lung adenocarcinom…
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CLINICAL_TRIALS trial_result · 2016-06-01Clinical Trial Update: Influence of the Use of the Diabetic Drug Metformin on the Overall Survival and Treatment-related Toxicity in Advanced Stage Non-small Cell Lung Cancer Patients.
A completed clinical trial evaluated whether metformin use influences overall survival and treatment-related toxicity in patients with advan…
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CLINICAL_TRIALS research · 2016-06-01Clinical Trial Update: Monosialoganglioside(GM1) Preventing Neurotoxicity Induced by Cisplatin Contained Chemotherapy in NSCLC Patients [Phase 3]
This Phase 3 trial investigates whether monosialoganglioside GM1 can prevent neurotoxicity caused by cisplatin-containing chemotherapy in no…
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CLINICAL_TRIALS trial_result · 2016-05-26Clinical Trial Update: A Study of Alectinib (RO5424802) in Participants With Non-Small Cell Lung Cancer Who Have Anaplastic Lymphoma Kinase (ALK) Mutation and Failed Crizotinib Treatment [Phase 1, Phase 2]
Phase 1/2 study of alectinib in ALK-positive NSCLC patients who failed crizotinib; trial completed with results posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-05-25Clinical Trial Update: SORAVE - Sorafenib and Everolimus in Solid Tumors [Phase 1]
A Phase 1 trial evaluating sorafenib and everolimus in solid tumors, including non-small cell lung cancer, has completed.