Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-12-05Clinical Trial Update: Study of Pembrolizumab (MK-3475) in Participants With Advanced Non-small Cell Lung Cancer (MK-3475-025/KEYNOTE-025) [Phase 1]
Phase 1 study of pembrolizumab (MK-3475) in participants with advanced non-small cell lung cancer completed; results posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-12-02Clinical Trial Update: Phase I Study of Vorinostat in Combination With Docetaxel in Patients With Advanced and Relapsed Solid Malignancies. [Phase 1]
This Phase I trial evaluated vorinostat in combination with docetaxel in patients with advanced and relapsed solid malignancies, including n…
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CLINICAL_TRIALS trial_result · 2016-12-01Clinical Trial Update: Erlotinib Hydrochloride and Cabozantinib-s-Malate Alone or in Combination as Second or Third Line Therapy in Treating Patients With Stage IV Non-small Cell Lung Cancer [Phase 2]
This Phase 2 trial evaluates erlotinib hydrochloride alone or in combination with cabozantinib-s-malate as second- or third-line therapy for…
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CLINICAL_TRIALS research · 2016-12-01Clinical Trial Update: Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Non-Small Cell Lung Cancer [Phase 1]
This clinical trial update describes a Phase 1 study evaluating the combination of chemotherapy and radiation therapy for non-small cell lun…
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CLINICAL_TRIALS research · 2016-12-01Clinical Trial Update: SBRT in Multi-metastatic NSCLC Patients Which Are Pan-negative for Driver Mutations [Phase 2]
A Phase 2 trial is evaluating stereotactic body radiotherapy in multi-metastatic non-small cell lung cancer patients who are pan-negative fo…
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CLINICAL_TRIALS approval · 2016-11-30Clinical Trial Update: Afatinib Expanded Access Program
Boehringer Ingelheim's Afatinib Expanded Access Program has been approved for marketing for non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2016-11-29Clinical Trial Update: Efficacy/Safety of Imprime PGG With Cetuximab & Paclitaxel/Carboplatin Therapy in Pts With Untreated Advanced Non-Small Cell Lung Cancer [Phase 2]
Phase 2 trial evaluated Imprime PGG in combination with cetuximab and paclitaxel/carboplatin for untreated advanced non-small cell lung canc…
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CLINICAL_TRIALS trial_result · 2016-11-29Clinical Trial Update: SBRT Combination With rhGM-CSF and Tα1 for Stage IV NSCLC Patients Who Failed in Second-line Chemotherapy [Phase 2]
Phase 2 clinical trial evaluating stereotactic body radiotherapy in combination with rhGM-CSF and thymosin alpha-1 for stage IV non-small ce…
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CLINICAL_TRIALS research · 2016-11-29Clinical Trial Update: Phase II Trial of SBRT Compared With Conventional Radiotherapy for Oligometastatic Non-Small Cell Lung Cancer [Phase 2]
A Phase II study compares stereotactic body radiotherapy (SBRT) with conventional radiotherapy in patients with oligometastatic non-small ce…
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CLINICAL_TRIALS research · 2016-11-25Clinical Trial Update: Evaluation of PD1 / PDL1 Expression on Blood Cells & Tumor Tissue, Their Role as a Prognostic Target in NSCLC Patients
This clinical trial update examines PD-1 and PD-L1 expression on blood cells and tumor tissue to evaluate their potential as prognostic targ…
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CLINICAL_TRIALS trial_result · 2016-11-25Clinical Trial Update: Radiotherapy Combined With Thymosin for Metastatic NSCLC Patients Who Showed Stable Disease After First Line TKI Therapy [Phase 2]
Phase 2 clinical trial update examining the combination of radiotherapy and thymosin in metastatic non-small cell lung cancer patients who h…
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CLINICAL_TRIALS trial_result · 2016-11-23Clinical Trial Update: Safety, Tolerability, Pharmacokinetics and Anti-tumour Activity of AC0010 in Advanced Non Small Cell Lung Cancer [Phase 1, Phase 2]
This clinical trial update reports on safety, tolerability, pharmacokinetics and anti-tumor activity of AC0010 in advanced Non-Small Cell Lu…
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CLINICAL_TRIALS research · 2016-11-23Clinical Trial Update: Open Label, Prospective Study to Investigate Efficacy and Safety of AZD9291 in BM From NSCLC Patients With EGFR T790M [Phase 3]
Open-label Phase 3 study evaluating the efficacy and safety of osimertinib (AZD9291) in brain metastases from EGFR T790M-positive non-small …
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CLINICAL_TRIALS trial_result · 2016-11-23Clinical Trial Update: Post-marketing Surveillance Study of Docetaxel-Based Chemotherapy
A post-marketing surveillance study of docetaxel-based chemotherapy in non-small cell lung cancer and head and neck squamous cell carcinoma …
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CLINICAL_TRIALS research · 2016-11-21Clinical Trial Update: uPAR-PET for Prognostication in Patients With Non-small Cell Lung Cancer, Malignant Pleural Mesothelioma and Large Cell Neuroendocrine Carcinoma of the Lung [Phase 2]
Clinical trial update describing Phase 2 evaluation of uPAR-PET imaging as a prognostic tool in patients with Non-small cell lung cancer, ma…
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CLINICAL_TRIALS trial_result · 2016-11-18Clinical Trial Update: High-dose Icotinib Treatment Beyond Progression in EGFR Mutant NSCLC [Phase 2]
A Phase 2 clinical trial update evaluating high-dose icotinib beyond progression in patients with EGFR-mutant non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2016-11-18Clinical Trial Update: Azacitidine and Entinostat in Treating Patients With Newly Diagnosed Stage IA-IIIA Non-Small Lung Cancer Undergoing Surgery [Phase 1]
A Phase 1 study evaluating azacitidine and entinostat in newly diagnosed stage IA-IIIA non-small cell lung cancer patients undergoing surger…
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CLINICAL_TRIALS trial_result · 2016-11-18Clinical Trial Update: Study Investigating the Effect of Everolimus Monotherapy in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) [Phase 2]
A Phase 2 study evaluated everolimus as monotherapy in patients with advanced non-small cell lung cancer. The trial status is completed.
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FDA approval · 2016-11-17FDA Approved: GEMCITABINE — Supplemental Application (Hospira, Inc.)
FDA approved Hospira, Inc.'s supplemental application for gemcitabine under ANDA 079183. This represents approval of a supplemental submissi…
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CLINICAL_TRIALS trial_result · 2016-11-11Clinical Trial Update: Icotinib in Non-small Cell Lung Cancer Patients With Uncommon EGFR Mutation [Phase 2]
This document provides an update on a Phase 2 clinical trial evaluating icotinib in non-small cell lung cancer patients with uncommon EGFR m…
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CLINICAL_TRIALS approval · 2016-11-10Clinical Trial Update: LUX Lung Special Access Scheme Australia Named Patient Use (NPU)
Australia granted marketing approval for afatinib under the Special Access Scheme (Named Patient Use) for non-small cell lung cancer.
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FDA approval · 2016-11-04FDA Approved: ALECENSA — Supplemental Application (Genentech, Inc.)
The FDA approved a supplemental application for ALECENSA (alectinib hydrochloride) to update the label for its use in ALK-positive non-small…
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CLINICAL_TRIALS withdrawal · 2016-11-04Clinical Trial Update: A Study of RO5083945 in Combination With Cisplatin and Gemcitabine or Carboplatin and Paclitaxel in Patients With Advanced or Recurrent Non-Small Cell Lung Cancer of Squamous Histology Who Have Not Received Prior Chemotherapy for The Metastatic Disease [Phase 1]
A Phase 1 study of RO5083945 in combination with cisplatin and gemcitabine or carboplatin and paclitaxel for squamous non-small cell lung ca…
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: A Study of Avastin (Bevacizumab) in Patients With Non-Squamous Non-Small Cell Lung Cancer (NSCLC) [Phase 3]
A Phase 3 trial evaluating Avastin (bevacizumab) in non-squamous non-small cell lung cancer has completed. The document notes the trial stat…
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: A Study of Avastin (Bevacizumab) in Combination With Thoracic Radiation and Chemotherapy in Patients With Advanced Non-Squamous Non-Small Cell Lung Cancer. [Phase 1]
Phase 1 study of Avastin (bevacizumab) in combination with thoracic radiation and chemotherapy in patients with advanced non-squamous non-sm…