Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2017-01-31Clinical Trial Update: Stereotactic Radiosurgery and Systemic Dose Chemotherapy for Locally Advanced Lung Cancer [EARLY_Phase 1]
This clinical trial update describes a Phase 1 study combining stereotactic radiosurgery with systemic dose chemotherapy for locally advance…
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CLINICAL_TRIALS trial_result · 2017-01-27Clinical Trial Update: Intercalating and Maintenance Use of Iressa Versus Chemotherapy in Selected Advanced Non Small Cell Lung Cancer [Phase 3]
Phase 3 trial comparing intercalating and maintenance use of Iressa (gefitinib) versus chemotherapy in selected advanced non-small cell lung…
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CLINICAL_TRIALS trial_result · 2017-01-25Clinical Trial Update: Pemetrexed, Carboplatin, and Bevacizumab as First-Line Therapy in Treating Older Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer [Phase 2]
Phase 2 trial evaluating pemetrexed, carboplatin, and bevacizumab as first-line therapy in older patients with stage IIIB or IV non-small ce…
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CLINICAL_TRIALS research · 2017-01-25Clinical Trial Update: A Study Evaluating RO5479599 in Combination With Carboplatin and Paclitaxel in Participants With Advanced or Metastatic Non-Small-Cell Lung Cancer (NSCLC) of Squamous Histology [Phase 1, Phase 2]
A terminated Phase 1/2 study evaluating RO5479599 in combination with carboplatin and paclitaxel for advanced or metastatic squamous non-sma…
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FDA approval · 2017-01-24FDA Approved: XALKORI — Supplemental Application (Pfizer Laboratories Div Pfizer Inc)
FDA approved a supplemental application for XALKORI (crizotinib) submitted by Pfizer Laboratories Div Pfizer Inc. This notice confirms regul…
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CLINICAL_TRIALS trial_result · 2017-01-24Clinical Trial Update: Radiofrequency Ablation in Treating Patients With Stage I Non-Small Cell Lung Cancer [NA]
The study evaluated radiofrequency ablation as a treatment for Stage I non-small cell lung cancer, and results from the completed trial have…
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CLINICAL_TRIALS research · 2017-01-24Clinical Trial Update: PD-L1 and Other Immuno-markers Influenced by Osimertinib Treatment in Advanced NSCLC Patients
This clinical trial update discusses how osimertinib treatment in advanced non-small cell lung cancer influences PD-L1 and other immuno-mark…
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CLINICAL_TRIALS trial_result · 2017-01-24Clinical Trial Update: A Trial to Evaluate the Improvement in Lung Cancer Patients Receiving Radiation With or Without Brachytherapy [Phase 3]
This clinical trial update notes the completion of a Phase 3 study evaluating radiation with or without brachytherapy in patients with non-s…
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CLINICAL_TRIALS trial_result · 2017-01-23Clinical Trial Update: Study of Metatinib Tromethamine Tablet [Phase 1]
This document provides a Phase 1 clinical trial update for Metatinib Tromethamine Tablet investigating advanced or metastatic gastric cancer…
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CLINICAL_TRIALS trial_result · 2017-01-20Clinical Trial Update: Carboplatin and Paclitaxel Albumin-Stabilized Nanoparticle Formulation Followed by Radiation Therapy and Erlotinib in Treating Patients With Stage III Non-Small Cell Lung Cancer That Cannot Be Removed By Surgery [Phase 2]
Phase 2 clinical trial evaluating carboplatin and paclitaxel albumin-stabilized nanoparticle formulation with radiation therapy and erlotini…
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CLINICAL_TRIALS research · 2017-01-20Clinical Trial Update: EGFR-TKI Resistance Profile in Chinese Patients With Advanced EGFRm+ NSCLC
This clinical trial update describes observations on resistance patterns to EGFR tyrosine kinase inhibitors in Chinese patients with advance…
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FDA approval · 2017-01-19FDA Approved: CISPLATIN — Supplemental Application (WG Critical Care, LLC)
The FDA approved a supplemental application for cisplatin submitted by WG Critical Care, LLC.
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CLINICAL_TRIALS trial_result · 2017-01-19Clinical Trial Update: Gemcitabine and Docetaxel in Treating Patients With Recurrent Stage III or Stage IV Non-Small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial evaluating the combination of gemcitabine and docetaxel for patients with recurrent stage III or stage IV non-small…
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CLINICAL_TRIALS withdrawal · 2017-01-19Clinical Trial Update: Stereotactic Body Radiation Therapy in Treating Patients With Stage I or Stage II Non-Small Cell Lung Cancer [Phase 1, Phase 2]
A clinical trial evaluating stereotactic body radiation therapy for stage I–II non-small cell lung cancer has been withdrawn.
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CLINICAL_TRIALS research · 2017-01-19Clinical Trial Update: Therapeutic Resistance Prediction of Tyrosine Kinase Inhibitors
This clinical trial update discusses research on predicting resistance to tyrosine kinase inhibitors in non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2017-01-18Clinical Trial Update: Study of Two Doses of Pembrolizumab (MK-3475) Versus Docetaxel in Previously Treated Participants With Non-Small Cell Lung Cancer (MK-3475-010/KEYNOTE-010) [Phase 2, Phase 3]
Clinical trial comparing two doses of pembrolizumab vs docetaxel in previously treated non-small cell lung cancer; study completed with resu…
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CLINICAL_TRIALS trial_result · 2017-01-16Clinical Trial Update: A Study of Paclitaxel/Carboplatin With or Without Olaratumab (IMC-3G3) in Previously Untreated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) [Phase 2]
Phase 2 trial evaluating paclitaxel/carboplatin with or without olaratumab (IMC-3G3) in previously untreated locally advanced or metastatic …
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CLINICAL_TRIALS research · 2017-01-06Clinical Trial Update: Characterization of Peripheral Muscle Function in Patients With Non-small-cell Lung Cancer
An update on a clinical trial characterizing peripheral muscle function in patients with non-small cell lung cancer.
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CLINICAL_TRIALS research · 2017-01-06Clinical Trial Update: Comparison of Gene Mutations in Matched Samples in Advanced Nonsquamous NSCLC Using NGS [NA]
Clinical trial investigating gene mutation differences in matched samples from patients with advanced non-small cell lung cancer using next-…
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CLINICAL_TRIALS withdrawal · 2017-01-05Clinical Trial Update: Phase IIB/III Of TG4010 Immunotherapy In Patients With Stage IV Non-Small Cell Lung Cancer [Phase 2, Phase 3]
The Phase IIb/III trial of TG4010 immunotherapy in stage IV non-small cell lung cancer was terminated. No efficacy results are provided in t…
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CLINICAL_TRIALS trial_result · 2017-01-04Clinical Trial Update: S0709: Erlotinib With or Without Carboplatin and Paclitaxel in Stage IIIB or Stage IV Non-Small Cell Lung Cancer [Phase 2]
Phase 2 trial of Erlotinib with or without Carboplatin and Paclitaxel in stage IIIB/IV non-small cell lung cancer completed; results posted.
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CLINICAL_TRIALS research · 2017-01-04Clinical Trial Update: Endostar Plus EGFR-TKI(Epidermal Growth Factor Receptor-Tyrosine-Kinase Inhibitor) as a Treatment of EGFR Mutation-positive NSCLC [Phase 3]
This document describes an ongoing Phase 3 clinical trial evaluating Endostar in combination with an EGFR-TKI for EGFR mutation-positive non…
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CLINICAL_TRIALS research · 2017-01-02Clinical Trial Update: Clinical Study of YQ1 Plus Cisplatin-based Chemotherapy in Advanced NSCLC EGFR Wild Type [Phase 2]
A phase 2 clinical trial evaluating YQ1 plus cisplatin-based chemotherapy in advanced non-small cell lung cancer with EGFR wild-type status.…
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CLINICAL_TRIALS withdrawal · 2016-12-30Clinical Trial Update: Adjuvant Erlotinib Intercalating Chemotherapy or Adjuvant Chemotherapy Alone in NSCLC With Common EGFR Mutation [Phase 3]
A Phase 3 trial comparing adjuvant erlotinib intercalating with chemotherapy versus adjuvant chemotherapy alone in NSCLC with common EGFR mu…
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CLINICAL_TRIALS trial_result · 2016-12-29Clinical Trial Update: Sorafenib in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer [Phase 2]
A Phase 2 trial evaluating sorafenib in patients with stage IIIB or stage IV non-small cell lung cancer has completed.