Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2018-04-25Clinical Trial Update: Nivolumab in Treating Patients With Stage IV or Recurrent Lung Cancer With High Mutation Loads [Phase 2]
A Phase 2 trial of nivolumab for patients with Stage IV or recurrent non-small cell lung cancer has been withdrawn.
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CLINICAL_TRIALS trial_result · 2018-04-24Clinical Trial Update: Phase II Trial to Evaluate the Efficacy and Safety of HM61713 as the 1st-line NSCLC Anticancer Therapy [Phase 2]
A Phase II clinical trial update reports the efficacy and safety of HM61713 as first-line therapy for non-small cell lung cancer (NSCLC). Th…
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CLINICAL_TRIALS trial_result · 2018-04-24Clinical Trial Update: Phase II Safety and Tolerability Trial With Nab-Paclitaxel Plus Carboplatin Followed by Nab-Paclitaxel for First Line Treatment of NSCLC Subjects With ECOG PS 2 [Phase 2]
Phase II safety and tolerability trial evaluating nab-paclitaxel plus carboplatin followed by nab-paclitaxel as first-line treatment in non-…
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CLINICAL_TRIALS trial_result · 2018-04-24Clinical Trial Update: Phase I/II Trial to Evaluate Safety, Tolerability and Pharmacokinetic Profile of HM61713 in NSCLC Patients [Phase 1, Phase 2]
Phase I/II trial assessing safety, tolerability, and pharmacokinetics of HM61713 in non-small cell lung cancer has completed.
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CLINICAL_TRIALS trial_result · 2018-04-23Clinical Trial Update: Erlotinib and SBRT in Treating Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer [Phase 2]
Phase 2 clinical trial evaluating erlotinib with SBRT for locally advanced or metastatic non-small cell lung cancer has completed; results p…
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CLINICAL_TRIALS trial_result · 2018-04-23Clinical Trial Update: Pilot Trial of EGF Ointment for the Patients With EGFR-i Related Skin Side Effects [Phase 2, Phase 3]
A pilot Phase 2/Phase 3 trial evaluated an epidermal growth factor ointment to manage EGFR-inhibitor–related skin side effects in cancer pat…
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CLINICAL_TRIALS trial_result · 2018-04-20Clinical Trial Update: Local Therapies for Oligometastatic Non-Small Cell Lung Cancer Harboring Sensitizing EGFR Mutations [NA]
Clinical trial update indicating completion and posting of results for a study on local therapies in oligometastatic non-small cell lung can…
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CLINICAL_TRIALS trial_result · 2018-04-20Clinical Trial Update: Broncho-Adventitial Delivery of Paclitaxel to Extend Airway Patency in Malignant Airway Obstruction Patients [NA]
This is a completed clinical trial evaluating broncho-adventitial delivery of paclitaxel to extend airway patency in patients with malignant…
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FDA approval · 2018-04-18FDA Approved: TAGRISSO — Supplemental Application (AstraZeneca Pharmaceuticals LP)
The FDA approved a supplemental application for Tagrisso (osimertinib) from AstraZeneca, resulting in changes to its approved labeling.
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CLINICAL_TRIALS trial_result · 2018-04-18Clinical Trial Update: Oshadi D and Oshadi R in Combination With Docetaxel, as 2nd Line Therapy for Metastatic Non Small Cell Lung Cancer [Phase 2]
Phase 2 trial examining Oshadi D and Oshadi R in combination with docetaxel as second-line therapy for metastatic non-small cell lung cancer…
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FDA approval · 2018-04-17FDA Approved: ALIMTA — Supplemental Application (Eli Lilly and Company)
FDA approved a supplemental application for ALIMTA (pemetrexed disodium) from Eli Lilly and Company.
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CLINICAL_TRIALS withdrawal · 2018-04-17Clinical Trial Update: Pulmonary Interstitial Lymphography in Early Stage Lung Cancer [NA]
The Stanford University-sponsored trial 'Pulmonary Interstitial Lymphography in Early Stage Lung Cancer' has been terminated. The trial stat…
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CLINICAL_TRIALS withdrawal · 2018-04-17Clinical Trial Update: A Safety Study of Nivolumab in Combination With Ipilimumab in Participants With Advanced Non-small Cell Lung Cancer [Phase 3]
A Phase 3 safety study evaluating nivolumab in combination with ipilimumab for advanced non-small cell lung cancer has been withdrawn.
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CLINICAL_TRIALS trial_result · 2018-04-13Clinical Trial Update: Study Evaluating the Safety Of HKI-272 (Neratinib) In Subjects With Advanced Non-Small Cell Lung Cancer [Phase 2]
Phase 2 trial evaluating neratinib (HKI-272) in subjects with advanced non-small cell lung cancer has completed, and results have been poste…
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CLINICAL_TRIALS trial_result · 2018-04-13Clinical Trial Update: Irinotecan for Previously Treated, Advanced, Non-Small Cell Lung Cancer [Phase 1, Phase 2]
A Phase 1/Phase 2 trial of irinotecan for previously treated, advanced non-small cell lung cancer was terminated, with results posted in 201…
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CLINICAL_TRIALS research · 2018-04-12Clinical Trial Update: Salivary Biomarkers for Non-small Cell Lung Cancer Detection
This clinical trial update reports ongoing research on salivary biomarkers for detecting non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2018-04-10Clinical Trial Update: Phase 2 Study of AUY922 in NSCLC Patients With Exon 20 Insertion Mutations in EGFR [Phase 2]
Phase 2 study of luminespib (AUY922) in non-small cell lung cancer with EGFR exon 20 insertion mutations has completed. Results were posted …
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CLINICAL_TRIALS trial_result · 2018-04-06Clinical Trial Update: Effects of Matuzumab in Combination With Pemetrexed for the Treatment of Advanced Lung Cancer [Phase 2]
A Phase 2 trial evaluating matuzumab in combination with pemetrexed for advanced non-small cell lung cancer has completed, with results post…
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CLINICAL_TRIALS trial_result · 2018-04-05Clinical Trial Update: Chemotherapy Combination With Local Radiotherapy and rhGM-CSF for Oligometastatic Stage IV NSCLC Patients [NA]
Clinical trial update on using chemotherapy in combination with local radiotherapy and rhGM-CSF for oligometastatic stage IV non-small cell …
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CLINICAL_TRIALS trial_result · 2018-04-03Clinical Trial Update: Erlotinib Plus Tivantinib (ARQ 197) Versus Single Agent Chemotherapy in Locally Advanced or Metastatic Non-Small Cell Lung Cancer [Phase 2]
Phase 2 trial comparing erlotinib plus tivantinib (ARQ 197) versus single-agent chemotherapy in locally advanced or metastatic non-small cel…
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CLINICAL_TRIALS trial_result · 2018-04-02Clinical Trial Update: Combination Checkpoint Inhibitor Plus Erlotinib or Crizotinib for EGFR or ALK Mutated Stage IV Non-small Cell Lung Cancer [Phase 1]
A Phase 1 trial evaluating a checkpoint inhibitor in combination with erlotinib or crizotinib for EGFR- or ALK-mutated stage IV non-small ce…
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CLINICAL_TRIALS withdrawal · 2018-04-02Clinical Trial Update: Endobronchial Ultrasound Guided Transbronchial Needle Aspiration (EBUS-TBNA) for Mediastinal Re-staging of Non-small Cell Lung Cancer(NSCLC) [NA]
A clinical trial evaluating endobronchial ultrasound-guided transbronchial needle aspiration for mediastinal re-staging in non-small cell lu…
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CLINICAL_TRIALS trial_result · 2018-03-30Clinical Trial Update: A Study Evaluating Safety and Pharmacokinetics of ABBV-221 in Subjects With Advanced Solid Tumor Types Likely to Exhibit Elevated Levels of Epidermal Growth Factor Receptor [Phase 1]
A Phase 1 trial evaluating the safety and pharmacokinetics of ABBV-221 in adults with advanced solid tumors likely to overexpress EGFR was t…
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CLINICAL_TRIALS trial_result · 2018-03-29Clinical Trial Update: AUY922 for Advanced ALK-positive NSCLC [Phase 2]
Phase 2 trial update reporting results for AUY922 (ganetespib) in advanced ALK-positive non-small cell lung cancer; results have been posted…
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CLINICAL_TRIALS trial_result · 2018-03-29Clinical Trial Update: Trial of a Vaccination With Tumor Antigen-loaded Dendritic Cell-derived Exosomes [Phase 2]
Phase 2 trial evaluating a tumor antigen-loaded dendritic cell-derived exosome vaccine for non-small cell lung cancer has completed.