Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-09-13Clinical Trial Update: Safety And Efficacy Of Crizotinib (Regulatory Post Marketing Commitment Plan)
Clinical trial update reporting safety and efficacy data for crizotinib under a regulatory post-marketing commitment plan for non-small cell…
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CLINICAL_TRIALS trial_result · 2019-09-12Clinical Trial Update: Randomized Phase III Trial of Surgery Alone or Surgery Plus Preoperative Gemcitabine-Cisplatin in Early Stages NSCLC [Phase 3]
A randomized Phase III trial comparing surgery alone to surgery plus preoperative gemcitabine-cisplatin in early-stage non-small cell lung c…
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CLINICAL_TRIALS trial_result · 2019-09-12Clinical Trial Update: Pembrolizumab Alone and In Combination With Acalabrutinib (ACP-196) in Subjects With Advanced Non-small Cell Lung Cancer [Phase 2]
Phase 2 trial evaluating pembrolizumab alone and in combination with acalabrutinib in advanced non-small cell lung cancer has completed with…
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CLINICAL_TRIALS trial_result · 2019-09-12Clinical Trial Update: A Comparison of Two Doses of Pemetrexed in Patients Who Have Lung Cancer [Phase 3]
A Phase 3 trial comparing two doses of pemetrexed in non-small cell lung cancer has completed.
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CLINICAL_TRIALS trial_result · 2019-09-12Clinical Trial Update: Combination of Cetuximab and NK Immunotherapy for Recurrent Non-small Cell Lung Cancer [Phase 1, Phase 2]
Clinical trial updating the combination of cetuximab with NK immunotherapy for recurrent non-small cell lung cancer (Phase 1/Phase 2) has co…
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CLINICAL_TRIALS trial_result · 2019-09-12Clinical Trial Update: Combination of Cryosurgery and NK Immunotherapy for Advanced Non-Small Cell Lung Cancer [Phase 1, Phase 2]
Phase 1/2 trial evaluating the combination of cryosurgery and NK cell immunotherapy for metastatic non-small cell lung cancer has completed.
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CLINICAL_TRIALS trial_result · 2019-09-12Clinical Trial Update: Safety and Efficiency of γδ T Cell Against Non Small Lung Cancer ( Without EGFR Mutation) [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating safety and efficacy of γδ T cell therapy for non-small cell lung cancer without EGFR mutation.
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CLINICAL_TRIALS trial_result · 2019-09-12Clinical Trial Update: High-activity Natural Killer Immunotherapy for Small Metastases of Non-small Cell Lung Cancer [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating a high-activity natural killer immunotherapy for small metastases in non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2019-09-10Clinical Trial Update: Safety & Efficacy Study of EGF Cancer Vaccine to Treat Stage IV Biomarker Positive, Wild Type EGF-R NSCLC Patients [Phase 3]
Phase 3 trial update for an EGF cancer vaccine in stage IV biomarker-positive, wild-type EGFR non-small cell lung cancer; study terminated.
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CLINICAL_TRIALS trial_result · 2019-09-10Clinical Trial Update: Phase 2 Study of MGCD265 in Patients With Non-Small Cell Lung Cancer With Activating Genetic Alterations in MET [Phase 2]
Phase 2 trial of MGCD265 in non-small cell lung cancer with activating MET alterations has completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-09-10Clinical Trial Update: Phase 2 Etirinotecan Pegol in Refractory Brain Metastases & Advanced Lung Cancer / Metastatic Breast Cancer [Phase 2]
Phase 2 trial update for etirinotecan pegol in refractory brain metastases, extensive-stage small cell lung cancer, recurrent NSCLC, metasta…
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CLINICAL_TRIALS trial_result · 2019-09-10Clinical Trial Update: Study of KN046 With Chemotherapy in First Line Advanced NSCLC [Phase 2]
Phase 2 clinical trial update for KN046 in combination with chemotherapy as first-line treatment for advanced non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2019-09-06Clinical Trial Update: Erlotinib or Placebo Following Chemoradiotherapy (Chemo/RT) in Stage III Non-Small Cell Lung Cancer (NSCLC) [Phase 3]
Phase 3 trial comparing erlotinib versus placebo after chemoradiotherapy in stage III non-small cell lung cancer completed with posted resul…
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FDA approval · 2019-09-05FDA Approved: DOCETAXEL — Supplemental Application (Mylan Institutional LLC)
FDA approved a supplemental application for docetaxel (docetaxel anhydrous) by Mylan Institutional LLC under ANDA 210072.
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CLINICAL_TRIALS trial_result · 2019-08-28Clinical Trial Update: Phase 3 Trial in Squamous Non Small Cell Lung Cancer Subjects Comparing Ipilimumab Plus Paclitaxel and Carboplatin Versus Placebo Plus Paclitaxel and Carboplatin [Phase 3]
Phase 3 trial in squamous non-small cell lung cancer comparing ipilimumab with paclitaxel and carboplatin to placebo with paclitaxel and car…
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CLINICAL_TRIALS trial_result · 2019-08-28Clinical Trial Update: A Study to Demonstrate the Benefit of a New Kind of Anti-cancer Treatment [PReferentially Expressed Antigen of MElanoma (PRAME) Immunotherapy] for Patients With Non-Small Cell Lung Cancer (NSCLC), After Removal of Their Tumor [Phase 2]
Phase 2 trial evaluating a PRAME-targeted immunotherapy for non-small cell lung cancer after tumor removal.
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CLINICAL_TRIALS trial_result · 2019-08-28Clinical Trial Update: Olmutinib Trial in T790M (+) NSCLC Patients Detected by Liquid Biopsy Using BALF Extracellular Vesicular DNA [Phase 2]
Phase 2 trial update evaluating olmutinib in T790M-positive non-small cell lung cancer detected via liquid biopsy in BALF extracellular vesi…
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CLINICAL_TRIALS trial_result · 2019-08-28Clinical Trial Update: Study of ADCT-502 in Patients With Advanced Solid Tumors Withhuman Epidermal Growth Factor Receptor-2 (HER2) Expression [Phase 1]
Phase 1 study of ADCT-502 in HER2-expressing advanced solid tumors including breast cancer and non-small cell lung cancer has terminated wit…
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CLINICAL_TRIALS trial_result · 2019-08-26Clinical Trial Update: Study of Pembrolizumab (MK-3475) Versus Platinum-Based Chemotherapy for Participants With Programmed Cell Death-Ligand 1 (PD-L1)-Positive Advanced or Metastatic Non-Small Cell Lung Cancer (MK-3475-042/KEYNOTE-042)-China Extension Study [Phase 3]
Phase 3 study comparing pembrolizumab to platinum-based chemotherapy in PD-L1–positive advanced/metastatic non-small cell lung cancer (China…
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CLINICAL_TRIALS trial_result · 2019-08-21Clinical Trial Update: Study of Anlotinib Combined With Osimertinib as Second-line Treatment in Stage IIIb-IV NSCLC With Confirmed EGFRm and T790M [Phase 2]
A Phase 2 clinical trial evaluating the combination of Anlotinib with Osimertinib as second-line therapy for stage IIIb-IV non-small cell lu…
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CLINICAL_TRIALS trial_result · 2019-08-21Clinical Trial Update: Phase 2 Study of Pyrotinib in Previously Treated Patients With NSCLC Having EGFR or ERBB2 Exon 20 Insertion Mutation [Phase 2]
Phase 2 study investigating Pyrotinib in previously treated non-small cell lung cancer with EGFR or ERBB2 exon 20 insertion mutations.
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FDA approval · 2019-08-15FDA Approved: ROZLYTREK — Original Application (Genentech, Inc.)
The FDA granted approval of Rozlytrek (entrectinib) in an original NDA for adult and pediatric patients with solid tumors that harbor NTRK g…
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CLINICAL_TRIALS trial_result · 2019-08-15Clinical Trial Update: A Study to Determine the Efficiency For Brain Metastasis NSCLC Patients Treated With Icotinib Alone or Combined With Radiation Therapy [Phase 3]
Phase 3 trial evaluating icotinib alone vs icotinib with radiation therapy for brain metastases in non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2019-08-15Clinical Trial Update: Safety and Efficacy Study of TQ-B3101 in Patients With ROS1-positive Non-Small Cell Lung Cancer (NSCLC) [Phase 2]
Phase 2 clinical trial update evaluating TQ-B3101 for ROS1-positive non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2019-08-12Clinical Trial Update: Afatinib (BIBW 2992) in Advanced Non-Small Cell Lung Cancer Patients With EGFR Mutation [Phase 3]
Phase 3 trial update of afatinib in advanced non-small cell lung cancer with EGFR mutation completed; results posted.