Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Adagrasib + SRS for Patients With Metastatic KRAS G12C-mutated NSCLC With Untreated Brain Metastases [Phase 2]
Phase 2 clinical trial evaluating the combination of adagrasib with stereotactic radiosurgery for metastatic KRAS G12C-mutated non-small cel…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Study to Assess the Efficacy and Safety of Rina-S in Participants With Non-small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial is evaluating the efficacy and safety of Rina-S in participants with Non-small cell lung cancer and is currently re…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: A Study to See How Well and How Safely Different Treatments Work in a Group of Participants With Non-Small Cell Lung Cancer (NSCLC) [Phase 1, Phase 2]
This clinical trial update describes a Roche-sponsored Phase 1/2 study in non-small cell lung cancer to evaluate how well and how safely dif…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Study of Inlexisertib (DCC-3116) in Participants With RAS/MAPK Pathway Mutant Solid Tumors [Phase 1]
A Phase 1 study of Inlexisertib (DCC-3116) in patients with RAS/MAPK pathway mutant solid tumors, including Non-Small Cell Lung Cancer, has …
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Beamion LUNG-3: A Study to Test Whether Zongertinib Helps People With Surgically Removed, Non-small Cell Lung Cancer With HER2 Mutations Compared With Standard Treatment [Phase 3]
A Phase 3 trial (LUNG-3) is evaluating Zongertinib vs standard treatment in patients with surgically removed non-small cell lung cancer harb…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Trial to Evaluate Acasunlimab and Pembrolizumab Combination Superiority Over Standard of Care Docetaxel in Non-Small Cell Lung Cancer (ABBIL1TY NSCLC-06) [Phase 3]
Phase 3 trial to evaluate acasunlimab plus pembrolizumab vs docetaxel in PD-L1-positive non-small cell lung cancer is currently active but n…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Adjuvant Pembrolizumab vs Observation Following Curative Resection for Stage I Non-small Cell Lung Cancer (NSCLC) With Primary Tumors Between 1-4 cm [Phase 2]
A Phase 2 clinical trial evaluating adjuvant pembrolizumab versus observation after curative resection in patients with stage I non-small ce…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Lumbar Punctures for the Detection of ctDNA in the Cerebrospinal Fluid of Patients With Stage III and IV Non-Small Cell Lung Cancer [NA]
This clinical trial entry describes a study evaluating lumbar punctures to detect circulating tumor DNA in the cerebrospinal fluid of patien…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: A Study of Lorlatinib in Combination With Ramucirumab in People With Lung Cancer [Phase 1, Phase 2]
This is a Phase 1/Phase 2 clinical trial testing lorlatinib in combination with ramucirumab in people with non-small cell lung cancer. The s…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Alectinib Pharmacokinetic in Patients With NSCLC [Phase 1, Phase 2]
This clinical trial update describes a pharmacokinetic study of alectinib in patients with non-small cell lung cancer (ALK mutation), spanni…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: JS212 Plus JS111 in EGFR-Mutant Advanced NSCLC: A Phase II Study [Phase 2]
A Phase II trial of JS212 plus JS111 for EGFR-mutant non-small cell lung cancer is not yet recruiting.
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Pulmonary Rehabilitation in Advanced Non-small Cell Lung Cancer Patients [NA]
A clinical trial update for a study evaluating pulmonary rehabilitation in patients with advanced non-small cell lung cancer, including sarc…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Dose Determining Study of EXS74539 (REC-4539) in Participants With Select Solid Tumors [Phase 1]
This clinical trial update reports a Phase 1 dose-determining study of EXS74539 (REC-4539) in participants with select solid tumors, current…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Osimertinib Induction and Maintenance for Chemo-ineligible Stage III Unresectable EGFR+ NSCLC: Single-arm Study [Phase 2]
Phase 2 single-arm trial assessing osimertinib induction and maintenance for chemo-ineligible, unresectable stage III EGFR-positive non-smal…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A Study to Compare the Combination of BMS-986504 With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion [Phase 2, Phase 3]
This is a phase 2/3 clinical trial evaluating BMS-986504 plus pembrolizumab and chemotherapy versus placebo plus pembrolizumab and chemother…
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: Real World Evaluation of Sotorasib Among Chinese Non-Small Cell Lung Cancer Patients
This document summarizes a real-world evaluation of sotorasib in Chinese patients with non-small cell lung cancer.
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4) [Phase 3]
KRYSTAL-4 is a Phase 3 trial evaluating adagrasib plus pembrolizumab and chemotherapy versus placebo plus pembrolizumab and chemotherapy in …
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: Study of Capmatinib in Indian Patients With MET Exon 14 Skipping Mutation Positive Advanced NSCLC. [Phase 4]
A Phase 4 trial evaluating capmatinib in Indian patients with MET exon 14 skipping mutation–positive advanced non-small cell lung cancer has…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A Clinical Trial of Adjuvant Intismeran (V940) With or Without Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) in High-Risk Stage I Non-Small Cell Lung Cancer (V940-014) [Phase 3]
Phase 3 trial evaluating adjuvant Intismeran (V940) with or without pembrolizumab coformulated with berahyaluronidase alfa (MK-3475A) in hig…
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: Study of Romiplostim for Chemotherapy-induced Thrombocytopenia in Adult Subjects With Non-small Cell Lung Cancer (NSCLC), Ovarian Cancer, or Breast Cancer [Phase 3]
A Phase 3 study evaluating romiplostim for chemotherapy-induced thrombocytopenia in adults with non-small cell lung cancer, ovarian cancer, …
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Surgery Versus Stereotactic Body Radiation Therapy for Stage I Non-Small Cell Lung Cancer
This clinical trial compares surgery versus stereotactic body radiation therapy for stage I non-small cell lung cancer, and the study is cur…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Atezolizumab Immunotherapy With or Without Tiragolumab for Patients With Unresectable Stage III NSCLC [Phase 2]
This clinical trial update describes a Phase 2 study of Atezolizumab with or without Tiragolumab for unresectable stage III non-small cell l…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Confocal Laser Endomicroscopy VERification [NA]
A clinical trial at Amsterdam University Medical Centers is investigating confocal laser endomicroscopy verification for lung cancer; the st…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A Study of VET3-TGI in Patients With Solid Tumors [Phase 1]
Phase 1 clinical trial update for VET3-TGI in patients with solid tumors, currently recruiting across multiple cancer types.
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001) [Phase 1, Phase 2]
Genmab is conducting a Phase 1/2 clinical trial of Rinatabart Sesutecan for multiple advanced solid tumors; recruitment is ongoing.