Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Enhanced Dermatological Care to Reduce Rash and Paronychia in Epidermal Growth Factor Receptor (EGRF)-Mutated Non-Small Cell Lung Cancer (NSCLC) Treated First-line With Amivantamab Plus Lazertinib [Phase 2]
Phase 2 trial update describes enhanced dermatologic care to reduce rash and paronychia in patients with epidermal growth factor receptor-mu…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of Stereotactic Radiosurgery (SRS) and Standard Treatment in People With Lung Cancer That Has Spread to the Brain [Phase 2]
This is a Phase 2 clinical trial evaluating stereotactic radiosurgery with standard treatment for non-small cell lung cancer that has spread…
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CLINICAL_TRIALS other · 2026-04-13Clinical Trial Update: Study of Radiation Therapy Followed by Atezolizumab in Stage II or III Non-small Cell Lung Cancer Patients [Phase 2]
Clinical trial update for a Phase 2 study evaluating radiation therapy followed by atezolizumab in stage II or stage III non-small cell lung…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) [Phase 2]
Phase 2 clinical trial evaluating amivantamab in combination with lazertinib or with platinum-based chemotherapy for EGFR-mutated locally ad…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of Participants in China With Non-Small-Cell Lung Cancer That is Unable to be Treated With Surgery
Hoffmann-La Roche is sponsoring a study in China for patients with non-small cell lung cancer that cannot be treated surgically; the trial i…
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CLINICAL_TRIALS other · 2026-04-13Clinical Trial Update: Centrally Confined 8Gy/1f to Tumor Core Followed by Concurrent Chemoradiotherapy for Unresectable Stage III NSCLC [Phase 1]
This Phase 1 trial evaluates centrally confined 8 Gy in 1 fraction to the tumor core followed by concurrent chemoradiotherapy for unresectab…
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: Phase Ib of L-NMMA and Pembrolizumab [Phase 1]
This completed Phase 1 trial evaluated the combination of L-NMMA with pembrolizumab across multiple cancers, with results posted.
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: Safety, PK and Efficacy of AI-061 in Advanced Solid Tumors [Phase 1]
Phase 1 update reporting safety, pharmacokinetics, and preliminary efficacy data for AI-061 in advanced solid tumors across multiple indicat…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Metformin Plus Tyrosine Kinase Inhibitors for Treatment of Patients With Non-small Cell Lung Cancer With EGFR Mutations [Phase 3]
A Phase 3 clinical trial is evaluating the combination of Metformin with EGFR tyrosine kinase inhibitors for treating patients with Non-Smal…
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors [Phase 2]
Jazz Pharmaceuticals is conducting a Phase 2 trial of Zanidatamab in HER2-expressing tumors across multiple cancers. The study is currently …
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: A Clinical Study of MK-1084 With Other Treatments for Non-small Cell Lung Cancer (MK-3475-01F) [Phase 1, Phase 2]
This clinical trial update describes a phase 1/2 study of MK-1084 in combination with other treatments for non-small cell lung cancer (MK-34…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Glutamine Plus L. Reuteri Prevents TKI Therapy-diarrhea in Patients With NSCLC [Phase 3]
A Phase 3 trial is investigating whether adding glutamine and the probiotic Lactobacillus reuteri can prevent diarrhea associated with EGFR-…
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: A Study to Compare Efficacy, Safety, and Immunogenicity of GME751 and EU-authorized Keytruda in Adult Participants With Untreated Metastatic Non-squamous Non-small Cell Lung Cancer (NSCLC) [Phase 3]
A Phase 3 trial comparing GME751 to pembrolizumab (Keytruda) in adults with untreated metastatic non-small cell lung cancer has completed.
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: Phase Ib Trial of the KRAS G12C Inhibitor Adagrasib (MRTX849) in Combination With the PARP Inhibitor Olaparib in Patients With KRAS G12C Mutated Advanced Solid Tumors, With a Focus on Gynecological, Breast, Pancreatic and KEAP1 Mutated Non-small Cell Lung Cancers [Phase 1]
Phase Ib trial evaluating adagrasib (KRAS G12C inhibitor) in combination with olaparib in KRAS G12C-mutated advanced solid tumors, focusing …
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Ivonescimab in Combination With Docetaxel in Advanced Non-Small Cell Lung Cancer [Phase 3]
A Phase 3 clinical trial evaluating Ivonescimab in combination with docetaxel for advanced non-small cell lung cancer is currently recruitin…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Study of Aerosolized Antibiotics and Pembrolizumab in Advanced Non-small Cell Lung Cancer [Phase 1]
This Phase 1 trial is evaluating the combination of aerosolized antibiotics with pembrolizumab in patients with advanced non-small cell lung…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Nitroglycerin Plus Radiotherapy Versus Conventional Radiotherapy in Patients With Lung Cancer. [NA]
A clinical trial is evaluating nitroglycerin as a radiosensitizer added to radiotherapy versus conventional radiotherapy in patients with no…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: IO102-IO103 in Combination With Pembrolizumab as First-line Treatment for Patients With Metastatic NSCLC, SCCHN, or mUBC [Phase 2]
Phase 2 trial results of IO102-IO103 in combination with pembrolizumab as first-line therapy for metastatic non-small cell lung cancer, head…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: A Study of Participant Reported Preference for Subcutaneous Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) Over Intravenous Pembrolizumab (MK-3475) Formulation in Multiple Tumor Types (MK-3475A-F11) [Phase 2]
Phase 2 study compares subcutaneous pembrolizumab coformulated with hyaluronidase alfa (MK-3475A) to intravenous pembrolizumab in multiple t…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: GEN1042 Safety Trial and Anti-tumor Activity in Participants With Malignant Solid Tumors [Phase 1, Phase 2]
GEN1042 is being evaluated in a Phase 1/2 safety study with indications across malignant solid tumors, including non-small cell lung cancer,…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Dose Escalation and Dose Expansion Study of RMC-6291 Monotherapy in Subjects With Advanced KRASG12C Mutant Solid Tumors [Phase 1]
Phase 1 study update for RMC-6291 monotherapy in KRASG12C-mutant solid tumors, outlining dose-escalation and dose-expansion cohorts in subje…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Combining Furmonertinib With Local Therapy for Inoperable Early-stage Lung Cancer: A Phase II Trial [Phase 2]
A Phase II study is exploring adding furmonertinib to local therapy for patients with inoperable, early-stage non-small cell lung cancer. Th…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: The Research Plan of Taiwan Precision Medicine
This document provides a clinical trial update on Taiwan's precision medicine research plan and notes that recruitment is ongoing for a stud…
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CLINICAL_TRIALS withdrawal · 2026-04-08Clinical Trial Update: Clinical Study of SHR-A1921 Combined With Adebrelimab and SHR-8068 With or Without Carboplatin in the Treatment of Advanced NSCLC [Phase 1, Phase 2]
A Phase 1/2 trial investigating SHR-A1921 combined with Adebrelimab and SHR-8068, with or without carboplatin, for advanced non-small cell l…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Delayed or Upfront Brain RAdiotherapy in Treatment naïve Lung Cancer Patients With Asymptomatic or Minimally Symptomatic Brain Metastases and ALK rEarrangements [Phase 1, Phase 2]
A phase 1/2 clinical trial is investigating optimal timing of brain radiotherapy (delayed vs upfront) in treatment‑naïve non-small cell lung…