Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-03-08Clinical Trial Update: Almonertinib Combined With Pyrotinib in the Treatment of Advanced NSCLC Patients With HER-2 Amplification/Mutation After EGFR-TKI Resistance [Phase 2]
A Phase 2 trial evaluating almonertinib combined with pyrotinib for advanced non-small cell lung cancer with HER-2 amplification/mutation af…
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CLINICAL_TRIALS trial_result · 2021-03-05Clinical Trial Update: CyberKnife Radiosurgical Treatment of Inoperable Early Stage Non-Small Cell Lung Cancer [Phase 2]
Phase 2 clinical trial update on CyberKnife radiosurgical treatment for inoperable early-stage non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2021-03-05Clinical Trial Update: Sensitivity of PDL-1-analysis From Pleural Effusion in Non-small Cell Lung Cancer
A completed clinical trial evaluating PD-L1 analysis sensitivity from pleural effusion in non-small cell lung cancer.
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FDA approval · 2021-03-03FDA Approved: LORBRENA — Supplemental Application (Pfizer Laboratories Div Pfizer Inc)
The FDA approved a supplemental application for Lorlatinib (LORBRENA) filed by Pfizer Laboratories Div Pfizer Inc.
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CLINICAL_TRIALS trial_result · 2021-02-26Clinical Trial Update: Study Comparing Veliparib Plus Carboplatin and Paclitaxel Versus Investigator's Choice of Standard Chemotherapy in Adults Receiving First Cytotoxic Chemotherapy for Metastatic or Advanced Non-Squamous Non-Small Cell Lung Cancer (NSCLC) and Who Are Current or Former Smokers [Phase 3]
Phase 3 trial comparing veliparib plus carboplatin and paclitaxel versus investigator's choice chemotherapy in first-line metastatic/advance…
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CLINICAL_TRIALS trial_result · 2021-02-26Clinical Trial Update: Adjuvant Toripalimab Plus Chemotherapy for EGFR/ALK Mutation Negative Stage II-IIIB(N2) NSCLC (LungMate-008) [Phase 3]
Phase 3 trial evaluating adjuvant toripalimab plus chemotherapy for EGFR/ALK mutation-negative stage II-IIIB(N2) non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2021-02-24Clinical Trial Update: Camrelizumab Combined With SRT/WBRT and Chemotherapy in Patients With Brain Metastases of Driven Gene-negative NSCLC [Phase 3]
Phase 3 trial evaluating camrelizumab with SRT/WBRT and chemotherapy in brain metastases from driver gene-negative non-small cell lung cance…
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CLINICAL_TRIALS trial_result · 2021-02-24Clinical Trial Update: GIOTRIF rPMS in Korean Patients With NSCLC
A completed clinical trial update for GIOTRIF rPMS in Korean patients with non-small cell lung carcinoma (NSCLC) has results posted.
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CLINICAL_TRIALS trial_result · 2021-02-23Clinical Trial Update: Bevacizumab or Pemetrexed Disodium Alone or In Combination After Induction Therapy in Treating Patients With Advanced Non-Squamous Non-Small Cell Lung Cancer [Phase 3]
A Phase 3 trial comparing bevacizumab or pemetrexed disodium alone or in combination after induction therapy in advanced non-squamous non-sm…
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CLINICAL_TRIALS trial_result · 2021-02-23Clinical Trial Update: Clinical Trial of Kanglaite Injection (KLTi) in Advanced Non-Small Cell Lung Cancer (NSCLC) [Phase 4]
Phase 4 clinical trial update for Kanglaite Injection (KLTi) in advanced non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2021-02-21Clinical Trial Update: Nintedanib in Molecularly Selected Patients With Advanced Non-Small Cell Lung Cancer [Phase 2]
This update presents results from a Phase 2 study of nintedanib in molecularly selected patients with advanced non-small cell lung cancer. T…
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CLINICAL_TRIALS trial_result · 2021-02-21Clinical Trial Update: Neoadjuvant Durvalumab/Anlotinib /Chemotherapy Plus Curative Resection in Stage III Non-Small-Cell Lung Cancer : A Single-arm Phase II Study [Phase 2]
A single-arm Phase II trial evaluating neoadjuvant durvalumab, anlotinib, and chemotherapy followed by curative resection in stage III non-s…
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CLINICAL_TRIALS trial_result · 2021-02-21Clinical Trial Update: Study of Patupilone in Patients With Brain Metastasis From Non-small Cell Lung Cancer [Phase 2]
Phase 2 trial update for patupilone in patients with brain metastasis from non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2021-02-21Clinical Trial Update: Open Label Extension Study of Conatumumab and Ganitumab (AMG 479) [Phase 2]
Open-label extension study of Conatumumab and Ganitumab (AMG 479) in a Phase 2 trial for advanced solid tumors; completed with results poste…
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CLINICAL_TRIALS trial_result · 2021-02-18Clinical Trial Update: A Study of Atezolizumab (MPDL3280A) Compared With a Platinum Agent (Cisplatin or Carboplatin) + (Pemetrexed or Gemcitabine) in Participants With Stage IV Non-Squamous or Squamous Non-Small Cell Lung Cancer (NSCLC) [IMpower110] [Phase 3]
Phase 3 trial comparing atezolizumab with platinum-based chemotherapy in stage IV NSCLC shows completed status with posted results.
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CLINICAL_TRIALS trial_result · 2021-02-16Clinical Trial Update: Efficacy and Safety Evaluation of Sintilimab in Patients With Advanced or Metastatic Non-squamous NSCLC [Phase 3]
Phase 3 trial evaluating sintilimab for advanced/metastatic non-squamous non-small cell lung cancer completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-02-16Clinical Trial Update: Pembrolizumab With Nab-Paclitaxel in Non-Small Cell Lung Cancer [Phase 1, Phase 2]
A clinical trial evaluating pembrolizumab in combination with nab-paclitaxel in non-small cell lung cancer has completed phases 1 and 2.
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CLINICAL_TRIALS trial_result · 2021-02-16Clinical Trial Update: Chemoradiotherapy in Stage III Non-small Cell Lung Cancer (NSCLC) [Phase 2]
Phase 2 trial update on chemoradiotherapy for Stage III non-small cell lung cancer; results posted after completion.
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CLINICAL_TRIALS trial_result · 2021-02-11Clinical Trial Update: Nimotuzumab Combined With Chemoradiotherapy for Unresectable Locally Advanced Squamous Cell Lung Cancer [Phase 2]
Phase 2 clinical trial evaluating nimotuzumab with chemoradiotherapy in unresectable locally advanced non-small cell lung cancer has complet…
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CLINICAL_TRIALS trial_result · 2021-02-11Clinical Trial Update: HX008 Plus Chemotherapy VS Pembrolizumab Plus Chemotherapy As the First-line Treatment in Participants With Advanced or Metastatic Nonsquamous Non-small Cell Lung Cancer [Phase 2, Phase 3]
A clinical trial comparing HX008 plus chemotherapy to pembrolizumab plus chemotherapy as first-line treatment for advanced or metastatic non…
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CLINICAL_TRIALS trial_result · 2021-02-05Clinical Trial Update: Phase 2 Study Evaluating Mid-position Strategy in Radiotherapy Treatment for Patients With a Locally Advanced Non-small Cell Lung Carcinoma [Phase 2]
Phase 2 trial evaluating a mid-position strategy in radiotherapy for locally advanced, non-metastatic non-small cell lung cancer; study comp…
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FDA approval · 2021-02-03FDA Approved: TEPMETKO — Original Application (EMD Serono, Inc.)
The FDA approves Tepmetko (tepotinib hydrochloride) under an original NDA for adults with metastatic non-small cell lung cancer harboring ME…
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CLINICAL_TRIALS trial_result · 2021-02-03Clinical Trial Update: Stereotactic Body Radiation Therapy (SBRT) in Newly Diagnosed Advanced Staged Lung Adenocarcinoma (Sindas) [Phase 3]
Phase 3 trial of SBRT in newly diagnosed stage IV EGFR-mutated non-small cell lung cancer was terminated.
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CLINICAL_TRIALS trial_result · 2021-02-02Clinical Trial Update: Trametinib and Docetaxel in Treating Patients With Recurrent or Stage IV KRAS Mutation Positive Non-small Cell Lung Cancer [Phase 2]
Phase 2 trial evaluating trametinib in combination with docetaxel for KRAS-mutant non-small cell lung cancer; results have been posted and t…
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CLINICAL_TRIALS trial_result · 2021-02-02Clinical Trial Update: A Phase 1/2 Study of SC-43 in Combination With Cisplatin [Phase 1, Phase 2]
Phase 1/2 study investigating SC-43 in combination with cisplatin in advanced cancers including non-small cell lung cancer and biliary tract…