Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-06-02Clinical Trial Update: Almonertinib Combined With Cerebral Radiation Treat Brain Metastases From EGFR Positive NSCLC [Phase 2]
Phase 2 trial evaluating almonertinib with cerebral radiation for brain metastases in EGFR-positive non-small cell lung cancer.
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FDA approval · 2021-05-28FDA Approved: LUMAKRAS — Original Application (Amgen Inc)
FDA approves Lumakras (sotorasib) from Amgen in an original application for the treatment of adults with KRAS G12C-mutant non-small cell lun…
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CLINICAL_TRIALS trial_result · 2021-05-24Clinical Trial Update: Pemetrexed in Maintenance in Patients With Impaired Renal Function, 2 Dose Calculation Strategies [Phase 4]
Phase 4 trial update evaluating pemetrexed in maintenance for patients with impaired renal function using two dose calculation strategies in…
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FDA approval · 2021-05-21FDA Approved: RYBREVANT — Original Application (Janssen Biotech, Inc.)
FDA approved RYBREVANT (amivantamab-vmjw) from Janssen Biotech, Inc. for adults with metastatic non-small cell lung cancer with EGFR exon 20…
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CLINICAL_TRIALS trial_result · 2021-05-18Clinical Trial Update: Aprepitant vs. Desloratadine in EGFR-TKIs Related Pruritus Treatment [Phase 2]
Phase 2 trial comparing aprepitant to desloratadine for pruritus related to EGFR-TKI therapy in non-small cell lung cancer has completed.
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CLINICAL_TRIALS trial_result · 2021-05-17Clinical Trial Update: A Study of Atezolizumab as Neoadjuvant and Adjuvant Therapy in Resectable Non-Small Cell Lung Cancer (NSCLC) - Lung Cancer Mutation Consortium (LCMC3) [Phase 2]
Phase 2 LCMC3 trial evaluating atezolizumab as neoadjuvant and adjuvant therapy in resectable non-small cell lung cancer has completed enrol…
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CLINICAL_TRIALS trial_result · 2021-05-13Clinical Trial Update: First Line Chemotherapy Treatment of Advanced Non-Small Cell Lung Cancer (NSCLC) [Phase 2]
Phase 2 trial update on first-line chemotherapy for advanced non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2021-05-13Clinical Trial Update: Study of Pemetrexed + Carboplatin + Bevacizumab + Enzastaurin Versus Pemetrexed + Carboplatin + Bevacizumab + Placebo in Participants With Non-Small Cell Lung Cancer Who Have Not Been Previously Treated With Chemotherapy [Phase 2]
A Phase 2 trial comparing pemetrexed/carboplatin/bevacizumab/enzastaurin versus pemetrexed/carboplatin/bevacizumab/placebo in previously unt…
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CLINICAL_TRIALS trial_result · 2021-05-13Clinical Trial Update: A Study of Enzastaurin and Erlotinib in Participants With Solid Tumors and Lung Cancer [Phase 1, Phase 2]
Phase 1/2 study evaluating enzastaurin plus erlotinib in solid tumors and non-small cell lung cancer has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-05-12Clinical Trial Update: Serial [18F]Thymidine (FLT)PET/CT as a Biomarker of Response in Pemetrexed Therapy for Non-Small Cell Lung Cancer [NA]
Clinical trial update on FLT-PET/CT as a biomarker of response for pemetrexed therapy in non-small cell lung cancer; study terminated with p…
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CLINICAL_TRIALS trial_result · 2021-05-11Clinical Trial Update: Almonertinib Treats Advanced NSCLC Patients With EGFR Mutations Who Are Safety Intolerant After Osimertinib Treatment [Phase 2]
Phase 2 trial update evaluating almonertinib in advanced non-small cell lung cancer patients with EGFR mutations who are safety intolerant a…
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CLINICAL_TRIALS trial_result · 2021-05-11Clinical Trial Update: Fluzoparib Combined With Camrelizumab for Maintenance Treatment of Locally Advanced Non-small Cell Lung Cancer [Phase 2]
Phase 2 trial update evaluating fluzoparib combined with camrelizumab as maintenance therapy in locally advanced non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2021-05-10Clinical Trial Update: Study of Niraparib, TSR-022, Bevacizumab, and Platinum-Based Doublet Chemotherapy in Combination With TSR-042 [Phase 1]
Phase 1 study evaluating Niraparib, TSR-022, Bevacizumab, and TSR-042 with platinum-based chemotherapy in patients with advanced or metastat…
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CLINICAL_TRIALS trial_result · 2021-05-10Clinical Trial Update: JY025 is a First-line Treatment for EGFR Mutated NSCLC Phase II and III Clinical Trials of Efficacy and Safety [Phase 2, Phase 3]
Clinical trial update indicates JY025 is being studied as first-line treatment for EGFR-mutated non-small cell lung cancer in Phase 2 and Ph…
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FDA approval · 2021-05-10FDA Approved: ERLOTINIB HYDROCHLORIDE — Original Application (Novadoz Pharmaceuticals LLC)
The FDA approved the original ANDA for erlotinib hydrochloride (generic) from Novadoz Pharmaceuticals LLC, making a generic version availabl…
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FDA approval · 2021-05-07FDA Approved: MEKINIST — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approved a supplemental application for Mekinist (trametinib) from Novartis Pharmaceuticals Corporation.
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CLINICAL_TRIALS trial_result · 2021-05-06Clinical Trial Update: A Study of Nivolumab in Advanced Non-Small Cell Lung Cancer (NSCLC) [Phase 1, Phase 2]
Clinical trial update for nivolumab in advanced non-small cell lung cancer (Phase 1/2) completed with results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-05-06Clinical Trial Update: Neoadjuvant Toripalimab Plus Platinum-based Doublet for Stage III Non-small Cell Lung Cancer [Phase 2]
Phase 2 neoadjuvant trial evaluating toripalimab with platinum-based doublet for stage III non-small cell lung cancer.
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FDA label_change · 2021-05-05FDA Approved: IRESSA — Supplemental Application (AstraZeneca Pharmaceuticals LP)
The FDA approved a supplemental application for IRESSA (gefitinib) from AstraZeneca, updating the drug’s labeling.
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CLINICAL_TRIALS trial_result · 2021-05-04Clinical Trial Update: Phase I Study of Accelerated Hypofractionated Image-Guided Radiation Therapy [NA]
Phase I study update for accelerated hypofractionated image-guided radiation therapy in non-small cell lung cancer; trial completed with res…
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CLINICAL_TRIALS trial_result · 2021-05-03Clinical Trial Update: Almonertinib Versus Osimertinib in the Patients With EGFR Mutations in Advanced NSCLC With Brain Metastases [Phase 3]
A Phase 3 trial comparing almonertinib to osimertinib in patients with EGFR-mutant advanced non-small cell lung cancer with brain metastases…
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CLINICAL_TRIALS trial_result · 2021-05-03Clinical Trial Update: Neoadjuvant Itraconazole in Non-small Cell Lung Cancer [EARLY_Phase 1]
Early-phase neoadjuvant trial evaluating itraconazole in non-small cell lung cancer has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-04-29Clinical Trial Update: Neoadjuvant Chemotherapy and Tilelizumab in Stage III(cTNM-IIIA.IIIB)Non-small-cell Lung Cancer [Phase 2]
Clinical trial update for neoadjuvant chemotherapy with Tilelizumab in stage III non-small-cell lung cancer (Phase 2).
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CLINICAL_TRIALS trial_result · 2021-04-27Clinical Trial Update: TAGRISSO (Osimertinib) in NSCLC Patients in Whom T790 Mutations Are Detected by Liquid Biopsy [Phase 2]
Phase 2 trial update of TAGRISSO (osimertinib) in NSCLC patients with T790M mutations detected by liquid biopsy.
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CLINICAL_TRIALS trial_result · 2021-04-21Clinical Trial Update: A Neoadjuvant Study of Sintilimab Plus Platinum Doublet Chemotherapy in IIIA(N2) Stage NSCLC [Phase 3]
A Phase 3 neoadjuvant trial evaluating sintilimab plus platinum doublet chemotherapy for stage IIIA(N2) non-small cell lung cancer is report…