Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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FDA approval · 2024-05-10FDA Approved: CISPLATIN — Original Application (Apotex Corp.)
FDA approved the original application for cisplatin from Apotex Corp., enabling the generic version to be marketed in the United States.
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CLINICAL_TRIALS trial_result · 2024-05-09Clinical Trial Update: Exploring the Theragnostic Value of Osimertinib in EGFR-mutated Lung Cancer (THEROS) [Phase 2]
Phase 2 trial update evaluating the theragnostic value of osimertinib in epidermal growth factor receptor-mutated non-small cell lung cancer…
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CLINICAL_TRIALS trial_result · 2024-05-09Clinical Trial Update: Rigosertib Plus Nivolumab for KRAS+ NSCLC Patients Who Progressed on First-Line Treatment [Phase 1, Phase 2]
Completed Phase 1/2 trial evaluating the combination of rigosertib and nivolumab in KRAS-positive non-small cell lung cancer patients who pr…
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CLINICAL_TRIALS research · 2024-05-09Clinical Trial Update: Neoadjuvant Targeted Therapy in Patients With Resectable EGFR-mutated Lung Squamous Cell Carcinoma [Phase 2]
This is a Phase 2 clinical trial evaluating neoadjuvant EGFR-targeted therapy in patients with resectable EGFR-mutated lung squamous cell ca…
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CLINICAL_TRIALS trial_result · 2024-05-09Clinical Trial Update: Study of Carfilzomib With Irinotecan in Irinotecan-Sensitive Malignancies and Small Cell Lung Cancer Patients [Phase 1, Phase 2]
Phase 1/2 trial evaluating the combination of carfilzomib with irinotecan in irinotecan-sensitive cancers and small cell lung cancer has com…
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CLINICAL_TRIALS trial_result · 2024-05-09Clinical Trial Update: Shenlingcao Oral Liquid for Patients With Stage II or IIIA NSCLC [Phase 4]
Phase 4 clinical trial update on Shenlingcao Oral Liquid for patients with stage II/IIIa non-small cell lung cancer following chemotherapy. …
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CLINICAL_TRIALS trial_result · 2024-05-09Clinical Trial Update: A Radiomic Model for Risk of Local Recurrence and DFS for T3 and T4 Non-small Cell Lung Cancer
A completed clinical trial evaluates a radiomic model to predict local recurrence risk and disease-free survival in patients with T3-T4 non-…
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CLINICAL_TRIALS research · 2024-05-09Clinical Trial Update: Patient-derived Organoid Drug Sensitivity Guided Treatment for Drug-resistant Recurrent Non-Small Cell Lung Cancer [NA]
This clinical trial investigates using patient-derived organoids to guide drug selection for patients with drug-resistant recurrent non-smal…
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CLINICAL_TRIALS other · 2024-05-09Clinical Trial Update: Neoadjuvant Nivolumab Combination Treatment in Resectable Non-small Cell Lung Cancer Patients [Phase 2]
Phase 2 trial evaluating neoadjuvant nivolumab in combination therapy for resectable non-small cell lung cancer across stages I–IIIa, curren…
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CLINICAL_TRIALS trial_result · 2024-05-08Clinical Trial Update: TRC102 and Temozolomide for Relapsed Solid Tumors and Lymphomas [Phase 1, Phase 2]
This clinical trial update reports the completion and posted results of a Phase 1/2 study evaluating TRC102 in combination with Temozolomide…
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CLINICAL_TRIALS trial_result · 2024-05-08Clinical Trial Update: Cisplatin, Docetaxel, and Nintedanib Before Surgery in Treating Patients With Previously Untreated Stage IB-IIIA Non-small Cell Lung Cancer [Phase 1]
Phase 1 study evaluating the combination of cisplatin, docetaxel, and nintedanib given before surgery in patients with previously untreated …
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: Using Microbiome to Predict Durvalumab Toxicity in Post- Concurrent Chemoradiation Therapy (CCRT) NSCLC Patients
The study aims to use microbiome profiles to predict toxicity from Durvalumab after chemoradiation in stage III non-small cell lung cancer. …
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CLINICAL_TRIALS trial_result · 2024-05-08Clinical Trial Update: eRAPID: Online Symptom Reporting in Lung Cancer [NA]
The eRAPID online symptom reporting study in thoracic cancers has completed, including non-small cell lung cancer, small-cell lung cancer, a…
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: A Study of Combining Cabozantinib and Atezolizumab for Advanced/Metastatic NSCLC (Cabatezo-1) [Phase 2]
A Phase 2 clinical trial evaluating the combination of cabozantinib and atezolizumab for advanced/metastatic non-small cell lung cancer; the…
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: Pulmonary Watershed Topographic Map Navigation for Lung Nodule Resection [NA]
A recruiting clinical trial evaluating a novel navigation technique using pulmonary watershed topography to guide lung nodule resection in s…
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CLINICAL_TRIALS trial_result · 2024-05-08Clinical Trial Update: Breathe Easier II: A Dyad-based Multiple Behavior Intervention [NA]
A completed clinical trial evaluating a dyad-based multiple behavior intervention aimed at improving self-management, physical activity, str…
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: A Phase I Clinical Study of QLC1101 in Patients With Advanced Solid Tumors [Phase 1]
Phase I clinical study of QLC1101 in patients with advanced solid tumors, including non-small cell lung cancer and colorectal cancer; the st…
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CLINICAL_TRIALS trial_result · 2024-05-07Clinical Trial Update: A First-in-human (FIH) Combination Treatment Study With a Single Dose Level of BMC128 [Phase 1]
A first-in-human Phase 1 trial of BMC128 in combination therapy evaluating a single dose level, across multiple cancers; status is active bu…
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CLINICAL_TRIALS research · 2024-05-07Clinical Trial Update: LIFE - Lung Cancer, Immunotherapy, Frailty, Effect
The LIFE trial update describes a study of non-small cell lung cancer examining immunotherapy with attention to frailty and quality-of-life …
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CLINICAL_TRIALS trial_result · 2024-05-07Clinical Trial Update: Selective HDAC6 Inhibitor ACY 241 in Combination With Nivolumab in Patients With Unresectable Non Small Cell Lung Cancer [Phase 1]
Phase 1 trial evaluating ACY-241 in combination with nivolumab for unresectable non-small cell lung cancer was terminated.
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CLINICAL_TRIALS trial_result · 2024-05-07Clinical Trial Update: First-line Treatment With Osimertinib in EGFR-mutated Non-small Cell Lung Cancer [Phase 2]
This ClinicalTrials.gov record reports a Phase 2 trial of first-line osimertinib for patients with EGFR-mutated non-small cell lung cancer; …
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CLINICAL_TRIALS research · 2024-05-07Clinical Trial Update: QOL After SURGERY and ADJUVANT Treatment
A ClinicalTrials.gov update notes a study evaluating quality of life after surgery and adjuvant treatment for non-small cell lung cancer tha…
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CLINICAL_TRIALS trial_result · 2024-05-06Clinical Trial Update: Quality of Life and Physical Fitness After Immune Checkpoint Inhibitors
A completed clinical trial evaluates quality of life and physical fitness in patients treated with immune checkpoint inhibitors for melanoma…
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CLINICAL_TRIALS trial_result · 2024-05-03Clinical Trial Update: Pembrolizumab Alone or Sequentially Following Single Fraction Non-ablative Radiation to One of the Target Lesions, in Previously Treated Patients With Stage IV NSCLC [Phase 2]
Phase 2 study assessing pembrolizumab alone or after targeted radiation to a lesion in previously treated patients with stage IV non-small c…
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CLINICAL_TRIALS trial_result · 2024-05-03Clinical Trial Update: Phase II Anti-PD1 Epigenetic Therapy Study in NSCLC. [Phase 2]
Phase II trial investigating an anti-PD1 epigenetic therapy in non-small cell lung cancer has completed. Results were posted in May 2024.