Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-06-04Clinical Trial Update: Chemotherapy With or Without Immune Checkpoint Inhibitors for Lung Cancer
A clinical trial is evaluating whether adding immune checkpoint inhibitors to chemotherapy improves outcomes in non-small cell lung cancer. …
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CLINICAL_TRIALS research · 2024-06-04Clinical Trial Update: Anlotinib Plus Immune Checkpoint Inhibitors for Lung Cancer [Phase 2, Phase 3]
A clinical trial update reporting ongoing phase 2 and phase 3 studies evaluating the combination of anlotinib with immune checkpoint inhibit…
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CLINICAL_TRIALS research · 2024-06-04Clinical Trial Update: Crizotinb or Standard Chemotherapy in Met Exon 14 Skipping Advanced NSCLC [Phase 2]
A Phase 2 trial tests crizotinib against standard chemotherapy in metastatic exon 14 skipping non-small cell lung cancer; the study is curre…
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CLINICAL_TRIALS research · 2024-06-04Clinical Trial Update: Improvement of Personalized Lung Cancer Care Through Digital Connection and Patient Participation (DigiNet) [NA]
This clinical trial update describes the DigiNet study aimed at improving personalized lung cancer care through digital connectivity and pat…
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CLINICAL_TRIALS trial_result · 2024-06-03Clinical Trial Update: A Dose Escalation Study of L-DOS47 in Recurrent or Metastatic Non-Squamous NSCLC [Phase 1]
Phase 1 dose-escalation study of L-DOS47 in patients with recurrent or metastatic non-squamous non-small cell lung cancer was terminated; re…
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CLINICAL_TRIALS research · 2024-06-03Clinical Trial Update: T-Cell Repertoire Sequencing: Assessing Pembrolizumab Efficacy in Advanced Non-small Lung Cancer [Phase 2]
A Phase 2 clinical trial is evaluating pembrolizumab efficacy in metastatic non-small cell lung cancer using T-cell repertoire sequencing; t…
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CLINICAL_TRIALS research · 2024-05-31Clinical Trial Update: An Exploratory Study of Efficacy and Safety of Iruplinalkib Tablets in Patients With ROS1 Positive Non-small Cell Lung Cancer [EARLY_Phase 1]
An exploratory Phase 1 trial assessing the efficacy and safety of Iruplinalkib tablets in patients with ROS1-positive non-small cell lung ca…
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CLINICAL_TRIALS trial_result · 2024-05-31Clinical Trial Update: A Randomised Phase II Trial of Osimertinib With or Without SRS for EGFR Mutated NSCLC With Brain Metastases [Phase 2]
This randomized Phase II trial evaluates osimertinib with or without stereotactic radiosurgery (SRS) in patients with EGFR-mutant non-small …
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CLINICAL_TRIALS withdrawal · 2024-05-31Clinical Trial Update: Using Infrared Spectroscopy to Analyze Volatile Organic Compounds (VOCs) in the Breath of Patients With Lung Cancer
The clinical trial evaluating infrared spectroscopy of breath volatile organic compounds in lung cancer patients has been terminated.
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CLINICAL_TRIALS trial_result · 2024-05-30Clinical Trial Update: Pembrolizumab Plus Bevacizumab and Chemotherapy for ALK-rearranged NSCLC With Persistent 5'ALK [Phase 2]
Phase 2 clinical trial update for ALK-rearranged non-small cell lung cancer evaluating pembrolizumab plus bevacizumab and chemotherapy, with…
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CLINICAL_TRIALS research · 2024-05-30Clinical Trial Update: A Study of SBRT Combined With Puterizumab in Intrapulmonary Metastasis From NSCLC [Phase 2]
A Phase 2 clinical trial evaluating SBRT in combination with Puterizumab for intrapulmonary metastases from non-small-cell lung cancer, with…
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CLINICAL_TRIALS research · 2024-05-30Clinical Trial Update: Osimertinib and Etoposide as First-Line Treatment in Osimertinib-Resistant Advanced EGFR-Mutant NSCLC [Phase 2]
Phase 2 trial evaluating osimertinib plus etoposide as first-line therapy in osimertinib-resistant advanced EGFR-mutant non-small cell lung …
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CLINICAL_TRIALS research · 2024-05-30Clinical Trial Update: Immune Treatment of Brain Metastasis of Lung Cancer Combined With Large-segmentation Precision Radiotherapy [Phase 2]
A Phase 2 clinical trial in non-small cell lung cancer with brain metastases is currently recruiting, evaluating an immune therapy in combin…
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CLINICAL_TRIALS trial_result · 2024-05-30Clinical Trial Update: The Efficacy and Safety of LMV-12 Combined With Osimertinib in NSCLC [Phase 1, Phase 2]
A phase 1/2 clinical trial is evaluating the combination of LMV-12 with Osimertinib for non-small cell lung cancer, including tumors with RE…
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CLINICAL_TRIALS trial_result · 2024-05-29Clinical Trial Update: Evaluate the Mediators of Sensitivity and Resistance to Nivolumab Plus Ipilimumab in Patients With Advanced NSCLCs [Phase 2]
Phase 2 trial evaluating biomarkers of sensitivity and resistance to nivolumab plus ipilimumab in advanced non-small cell lung cancer, with …
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CLINICAL_TRIALS trial_result · 2024-05-29Clinical Trial Update: A Study of Combination Amivantamab and Carboplatin-Pemetrexed Therapy, Compared With Carboplatin-Pemetrexed, in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Characterized by Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions [Phase 3]
Phase 3 trial evaluating amivantamab with carboplatin-pemetrexed versus carboplatin-pemetrexed alone in advanced/metastatic non-small cell l…
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CLINICAL_TRIALS trial_result · 2024-05-29Clinical Trial Update: Pulmonary sarcomatoid_MEDI4736+Treme [Phase 2]
A Phase 2 trial evaluating the combination of durvalumab and tremelimumab for pulmonary sarcomatoid carcinoma and non-small cell lung cancer…
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CLINICAL_TRIALS trial_result · 2024-05-29Clinical Trial Update: A Study of Combination Amivantamab and Carboplatin-Pemetrexed Therapy, Compared With Carboplatin-Pemetrexed, in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Characterized by Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions [Phase 3]
Phase 3 trial comparing amivantamab plus carboplatin-pemetrexed versus carboplatin-pemetrexed in advanced/metastatic non-small cell lung can…
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CLINICAL_TRIALS withdrawal · 2024-05-29Clinical Trial Update: JDQ443 for KRAS G12C NSCLC Brain Metastases [Phase 2]
A Phase 2 trial of JDQ-443 for KRAS G12C-mutant non-small cell lung cancer with brain metastases has been withdrawn.
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CLINICAL_TRIALS research · 2024-05-29Clinical Trial Update: Assessing an Oral EGFR Inhibitor, DZD9008 in Patients With Advanced Non-small Cell Lung Cancer(NSCLC) With EGFR Mutations (WU-KONG15) [NA]
Clinical trial update for DZD9008, an oral EGFR inhibitor, in patients with advanced non-small cell lung cancer with EGFR mutations. The stu…
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CLINICAL_TRIALS research · 2024-05-28Clinical Trial Update: Safety and Efficacy of Whole Brain LDRT+ICI+Intrathecal Chemotherapy in Refractory Meningeal Metastasis of Lung Cancer [Phase 1]
A Phase 1 clinical trial update evaluating safety and efficacy of combining whole-brain low-dose radiotherapy with a PD-1 inhibitor and intr…
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CLINICAL_TRIALS research · 2024-05-28Clinical Trial Update: a Single-arm, Single-center, Open Clinical Study
This update notes a single-arm, single-center, open-label clinical trial that is currently recruiting, evaluating treatment across multiple …
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CLINICAL_TRIALS trial_result · 2024-05-24Clinical Trial Update: A Study to Evaluate the Safety and Tolerability of Immunotherapy Combinations in Participants With Advanced Malignancies [Phase 1]
This Phase 1 trial evaluated the safety and tolerability of immunotherapy combinations across multiple advanced cancers and has completed.
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CLINICAL_TRIALS research · 2024-05-24Clinical Trial Update: Safety and Feasibility of Surgery After Conversion Therapy for Locally Advanced and Advanced NSCLC [NA]
Clinical trial update noting an ongoing study evaluating the safety and feasibility of surgery after conversion therapy for locally advanced…
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CLINICAL_TRIALS trial_result · 2024-05-24Clinical Trial Update: A Registry to Evaluate the Performance of the BDX-XL2 Test
This document reports a completed clinical trial registry evaluating the performance of the BDX-XL2 diagnostic test.