Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-06-26Clinical Trial Update: Neoadjuvant/Adjuvant Tislelizumab Combined With Anlotinib and Platinum Doublet Chemotherapy With Resectable NSCLC [Phase 2]
A Phase 2 trial exploring neoadjuvant/adjuvant tislelizumab with anlotinib and platinum chemotherapy for resectable non-small cell lung canc…
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CLINICAL_TRIALS research · 2024-06-26Clinical Trial Update: SRT Combined With Anlotinib for the Treatment of Brain Metastases From Non-small Cell Lung Cancer [NA]
This clinical trial is evaluating the combination of stereotactic radiotherapy (SRT) with anlotinib for brain metastases from non-small cell…
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CLINICAL_TRIALS withdrawal · 2024-06-26Clinical Trial Update: Study of Intravenous Telisotuzumab Vedotin in Combination Osimertinib or Standard of Care Chemotherapy to Assess Change in Disease Activity in Adult Participants With Non-Small Cell Lung Cancer That Has a Mutation in the Epidermal Growth Factor Receptor Gene and That Overexpresses the c-Met Protein [Phase 3]
A Phase 3 trial evaluating Telisotuzumab Vedotin in combination with Osimertinib or standard-of-care chemotherapy for EGFR-mutant, MET-overe…
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CLINICAL_TRIALS trial_result · 2024-06-25Clinical Trial Update: Phase 3 Study of Sitravatinib Plus Nivolumab vs Docetaxel in Patients With Advanced Non-Squamous Non-Small Cell Lung Cancer [Phase 3]
A Phase 3 study evaluating sitravatinib in combination with nivolumab versus docetaxel in advanced/metastatic non-squamous non-small cell lu…
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CLINICAL_TRIALS trial_result · 2024-06-25Clinical Trial Update: Phase III Study to Determine Efficacy of Durvalumab in Stage II-III Non-small Cell Lung Cancer (NSCLC) After Curative Intent Therapy. [Phase 3]
Phase III trial update evaluating durvalumab after curative-intent therapy in stage II-III non-small cell lung cancer; results were posted i…
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CLINICAL_TRIALS trial_result · 2024-06-25Clinical Trial Update: Durvalumab and Tremelimumab With or Without High or Low-Dose Radiation Therapy in Treating Patients With Metastatic Colorectal or Non-small Cell Lung Cancer [Phase 2]
Phase 2 trial evaluating durvalumab with tremelimumab, with or without radiation therapy, in metastatic colorectal cancer and metastatic non…
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CLINICAL_TRIALS research · 2024-06-25Clinical Trial Update: Evaluating the Safety and Efficacy of Pembrolizumab Combined With MWA for Advanced NSCLC [NA]
This registry entry describes a clinical study evaluating pembrolizumab in combination with microwave ablation (MWA) for advanced non-small …
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CLINICAL_TRIALS trial_result · 2024-06-25Clinical Trial Update: Phase I Study of the BBP-398 in Patients With Advance Solid Tumors [Phase 1]
Phase I study of BBP-398 in patients with advanced solid tumors, including advanced or metastatic non-small cell lung cancer, has been termi…
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CLINICAL_TRIALS research · 2024-06-25Clinical Trial Update: Hypofraction Radiotherapy for Locally Advanced Non-small Cell Lung Cancer [Phase 1, Phase 2]
A clinical trial update describes a phase 1/2 study of hypofractionated radiotherapy for locally advanced non-small cell lung cancer that is…
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CLINICAL_TRIALS trial_result · 2024-06-25Clinical Trial Update: BBP-398 in Combination With Osimertinib in Locally Advanced or Metastatic NSCLC Patients With EGFR Mutations [Phase 1]
Phase 1 trial evaluating BBP-398 in combination with Osimertinib for locally advanced or metastatic non-small cell lung cancer with EGFR mut…
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CLINICAL_TRIALS research · 2024-06-25Clinical Trial Update: TCR-T Cell Immunotherapy of Lung Cancer and Other Solid Tumors [Phase 1]
A Phase 1 clinical trial evaluating TCR-T cell immunotherapy for non-small cell lung cancer and other solid tumors, currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-06-25Clinical Trial Update: Study of Poziotinib in Japanese Patients With NSCLC [Phase 1, Phase 2]
A Phase 1/2 trial of Poziotinib in Japanese patients with non-small cell lung cancer was terminated, and results have been posted.
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CLINICAL_TRIALS research · 2024-06-25Clinical Trial Update: Study of CXCR5 Modified EGFR Targeted CAR-T Cells for Advanced NSCLC [EARLY_Phase 1]
An early Phase 1 clinical trial is recruiting for CXCR5-modified EGFR-targeted CAR-T cells to treat advanced non-small cell lung cancer, spo…
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CLINICAL_TRIALS trial_result · 2024-06-24Clinical Trial Update: Phase 1 Safety Study of Encorafenib in Chinese Patients With Advanced Metastatic BRAF V600E Mutant Solid Tumors [Phase 1]
Phase 1 safety study evaluating encorafenib in Chinese patients with advanced/metastatic BRAF V600E-mutant solid tumors, including melanoma …
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CLINICAL_TRIALS research · 2024-06-24Clinical Trial Update: Phase 1b/2 Study to Evaluate ABT-101 in Solid Tumor and NSCLC Patients [Phase 1, Phase 2]
A Phase 1b/2 clinical trial evaluating ABT-101 in advanced solid tumors and non-small cell lung cancer is currently recruiting.
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FDA approval · 2024-06-21FDA Approved: KRAZATI — Supplemental Application (Mirati Therapeutics, Inc)
The FDA approved a supplemental application for KRAZATI (adagrasib) submitted by Mirati Therapeutics, Inc.
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CLINICAL_TRIALS research · 2024-06-21Clinical Trial Update: A Prospective, Open-label, Single-center, Single-arm Phase II Clinical Study of Cadonilimab (AK104) Combined With Monotherapy Chemotherapy in Patients With Advanced Non-small Cell Lung Cancer With Negative Driver Genes and Failed Immunotherapy [Phase 2]
A Phase II open-label, single-arm study evaluating cadonilimab (AK104) in combination with chemotherapy for advanced non-small cell lung can…
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CLINICAL_TRIALS trial_result · 2024-06-20Clinical Trial Update: A Study of Selpercatinib (LY3527723) in Participants With Advanced or Metastatic RET Fusion-Positive Non-Small Cell Lung Cancer [Phase 3]
Clinical trial update for a Phase 3 study of selpercatinib in RET fusion-positive non-small cell lung cancer; results have been posted and t…
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CLINICAL_TRIALS trial_result · 2024-06-20Clinical Trial Update: A Study to Learn About How Itraconazole and Carbamazepine Affect the Level of BAY2927088 in the Blood When These Drugs Are Taken Together by Healthy Participants [Phase 1]
Phase 1 study evaluating how itraconazole and carbamazepine affect BAY2927088 blood levels in healthy participants; study completed.
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CLINICAL_TRIALS withdrawal · 2024-06-20Clinical Trial Update: The Effect of Combined General/Regional Anesthesia on Cancer Recurrence in Patients Having Lung Cancer Resections [NA]
A clinical trial assessing whether combined general and regional anesthesia affects cancer recurrence after lung cancer surgery; the study h…
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CLINICAL_TRIALS research · 2024-06-20Clinical Trial Update: Clinical Study of SHR-A1921 or SHR-A2009 in Previously Treated Advanced NSCLC [Phase 2]
Clinical trial update for SHR-A1921 or SHR-A2009 in previously treated advanced non-small cell lung cancer (Phase 2); the study is currently…
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CLINICAL_TRIALS other · 2024-06-18Clinical Trial Update: Tumor Cell Plasticity and Aggressiveness in Human Non-small Cell Lung Cancer
This clinical trial update describes a study on tumor cell plasticity and aggressiveness in non-small cell lung cancer, with recruitment not…
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CLINICAL_TRIALS withdrawal · 2024-06-17Clinical Trial Update: Central Nervous System Efficacy of Capmatinib in NSCLC With Brain Metastases With cfDNA Positive MET Alterations [Phase 2]
A Phase 2 trial evaluating capmatinib for CNS efficacy in non-small cell lung cancer with brain metastases and cfDNA-positive MET alteration…
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CLINICAL_TRIALS research · 2024-06-17Clinical Trial Update: Macrophage Imaging Using Ga-MMR-VHH2 in Lung Cancer Patients [Phase 2]
Phase 2 clinical trial investigating a gallium-labeled imaging agent Ga-MMR-VHH2 for non-small cell lung cancer patients; recruitment curren…
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CLINICAL_TRIALS research · 2024-06-17Clinical Trial Update: CPAP or BiPAP for Motion Mitigation During Radiotherapy [NA]
A University Medical Center Groningen trial is evaluating CPAP or BiPAP to mitigate motion during radiotherapy for NSCLC and other cancers, …