Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-07-25Clinical Trial Update: Befotertinib and Icotinib for NSCLC With Uncommon EGFR Mutations [Phase 2]
Phase 2 trial evaluating Befotertinib and Icotinib for metastatic non-small cell lung cancer with uncommon EGFR mutations (G719X, L861Q, S76…
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CLINICAL_TRIALS trial_result · 2024-07-24Clinical Trial Update: First-in-Human Dose Escalation Study of XMT-1536 in Cancers Likely to Express NaPi2b [Phase 1]
XMT-1536, an investigational NaPi2b-targeting agent from Mersana Therapeutics, completed a first-in-human Phase 1 dose-escalation study in c…
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CLINICAL_TRIALS trial_result · 2024-07-24Clinical Trial Update: First-in-Human Dose Expansion Study of XMT-1536 in Cancers Likely to Express NaPi2b [Phase 1]
First-in-human dose expansion Phase 1 trial of XMT-1536 targeting NaPi2b in cancers likely to express the transporter, including platinum-re…
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CLINICAL_TRIALS trial_result · 2024-07-24Clinical Trial Update: A Study of NBF-006 in Non-Small Cell Lung, Pancreatic, or Colorectal Cancer [Phase 1]
NBF-006's Phase 1 trial in non-small cell lung cancer, pancreatic cancer, and colorectal cancer has completed.
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CLINICAL_TRIALS trial_result · 2024-07-24Clinical Trial Update: Omitting of Lymphadenectomy is Acceptable for Lung Cancer Smaller Than 6 mm in Solid Size
The completed trial evaluated whether omitting lymphadenectomy is feasible and safe for very small non-small cell lung cancers with solid si…
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CLINICAL_TRIALS trial_result · 2024-07-24Clinical Trial Update: Evaluation of a Novel Microfluidic Device to Purify Metastatic Lung Cancer Patients CTC (Circulating Tumoral Cells)
A terminated clinical trial evaluating a novel microfluidic device to purify circulating tumor cells in patients with metastatic non-small c…
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CLINICAL_TRIALS research · 2024-07-24Clinical Trial Update: Efficacy and Safety of High-Dose Rate Brachytherapy With Immunotherapy and Chemotherapy as Second-Line Treatment for Advanced Non-Small Cell Lung Cancer
A clinical trial is evaluating high-dose rate brachytherapy combined with immunotherapy and chemotherapy as a second-line treatment for adva…
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CLINICAL_TRIALS trial_result · 2024-07-23Clinical Trial Update: A Study of Neoadjuvant Chemotherapy Plus Nivolumab Versus Neoadjuvant Chemotherapy Plus Placebo, Followed by Surgical Removal and Adjuvant Treatment With Nivolumab or Placebo for Participants With Surgically Removable Early Stage Non-small Cell Lung Cancer [Phase 3]
Phase 3 trial comparing neoadjuvant chemotherapy plus nivolumab versus chemotherapy plus placebo, followed by surgery and adjuvant therapy, …
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CLINICAL_TRIALS research · 2024-07-23Clinical Trial Update: Study of BEBT-109 in Subjects With Non-Small Cell Lung Cancer Carrying EGFR Exon 20 Insertion Mutations [Phase 2]
BEBT-109 is being studied in non-small cell lung cancer with EGFR exon 20 insertion mutations in a Phase 2 trial, which is currently not yet…
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CLINICAL_TRIALS trial_result · 2024-07-23Clinical Trial Update: A Multi-Centre, Prospective, Non-Interventional Study to Intensively Monitor the Safety of Osimertinib in Clinical Practice Among Chinese NSCLC Patients
This is a multi-centre, prospective, non-interventional study that intensively monitors the safety of osimertinib in Chinese patients with n…
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CLINICAL_TRIALS research · 2024-07-22Clinical Trial Update: Treatment of Pulmonary SUlcus, Pancoast and Chest Wall Non-small Cell Lung Cancer Employing Radiation, Immuno-oncology and Resection [Phase 2]
Phase 2 clinical trial update for non-small cell lung cancer involving Pancoast tumors and chest wall involvement, evaluating radiation, imm…
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CLINICAL_TRIALS research · 2024-07-22Clinical Trial Update: Study of Zirconium Zr 89 Crefmirlimab Berdoxam PET/CT in Subjects With Advanced or Metastatic Malignancies [Phase 2]
Phase 2 trial update for Zirconium-89 labeled Crefmirlimab Berdoxam PET/CT in advanced or metastatic cancers; the study is currently active …
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CLINICAL_TRIALS research · 2024-07-22Clinical Trial Update: Trial of Pulsed Electric Field Therapy in Patients With Late-stage Non-small Cell Lung Cancer [NA]
A clinical trial is evaluating pulsed electric field therapy for late-stage non-small cell lung cancer. The study is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-07-19Clinical Trial Update: A Study of Bevacizumab, Carboplatin, and Paclitaxel or Pemetrexed With or Without Atezolizumab in Chemotherapy-Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer (IMpower151) [Phase 3]
Phase 3 IMpower151 trial evaluating bevacizumab with chemotherapy, with or without atezolizumab, in chemo-naïve stage IV non-squamous non-sm…
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CLINICAL_TRIALS trial_result · 2024-07-19Clinical Trial Update: A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of HH2710 in Patient With Advanced Tumors [Phase 1, Phase 2]
Phase 1/2 study of HH2710 in patients with melanoma and other advanced tumors was terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2024-07-19Clinical Trial Update: Neoadjuvant Aliya™ PEF Soft Tissue Ablation With Systemic Therapy in Early-Stage Resectable NSCLC [Phase 4]
Phase 4 neoadjuvant trial of Aliya PEF Soft Tissue Ablation with systemic therapy in early-stage resectable non-small cell lung cancer has b…
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CLINICAL_TRIALS trial_result · 2024-07-19Clinical Trial Update: Feasibility Study of the Aliya System in the Treatment of Early Stage Non-small Cell Lung Cancer [NA]
This clinical trial update reports the completion of a feasibility study evaluating the Aliya System for early-stage non-small cell lung can…
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CLINICAL_TRIALS trial_result · 2024-07-18Clinical Trial Update: A Study of Non-Small Cell Lung Cancer (NSCLC) Patients Receiving Second-Line Nivolumab Monotherapy in Asia [Phase 3]
A Phase 3 clinical trial in Asia assessing second-line nivolumab monotherapy for non-small cell lung cancer has completed and posted results…
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CLINICAL_TRIALS research · 2024-07-18Clinical Trial Update: MYLUNG Consortium Part 3: Observational Study
This document reports a recruiting observational study in the MYLUNG Consortium Part 3 focusing on non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2024-07-18Clinical Trial Update: A Clinical Study to Evaluate the Tolerance, Pharmacokinetics and Efficacy of TQ-A3334 Tablets [Phase 1, Phase 2]
A Phase 1/2 trial evaluating tolerance, pharmacokinetics and efficacy of TQ-A3334 tablets for non-small cell lung cancer has been terminated…
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CLINICAL_TRIALS research · 2024-07-18Clinical Trial Update: Low Volume High Intensity Interval Training in Operated Lung Cancer Patients [NA]
A clinical trial is evaluating the effects of low-volume high-intensity interval training in operated lung cancer patients, including non-sm…
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CLINICAL_TRIALS research · 2024-07-18Clinical Trial Update: Therapeutic ResistAnce and Clonal Evolution Assessed With Liquid Biopsy in ICIs Treated NSCLC Patients
An ongoing clinical study is investigating therapeutic resistance and clonal evolution in non-small cell lung cancer patients treated with i…
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CLINICAL_TRIALS research · 2024-07-17Clinical Trial Update: QUILT-2.025 NANT Neoepitope Yeast Vaccine (YE-NEO-001): Adjuvant Immunotherapy Using a Personalized Neoepitope Yeast-Based Vaccine To Induce T-Cell Responses In Subjects W/ Previously Treated Cancers. [Phase 1]
Phase 1 trial update for YE-NEO-001, NantBioScience's personalized neoepitope yeast vaccine, evaluating adjuvant immunotherapy to elicit T-c…
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CLINICAL_TRIALS research · 2024-07-17Clinical Trial Update: Testing Tumor Tissue and Blood to Help Select Personalized Treatments for Patients With Suspected Lung Cancers
This is a recruiting clinical study evaluating tumor tissue and blood-based approaches to guide personalized treatments for patients with su…
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CLINICAL_TRIALS trial_result · 2024-07-16Clinical Trial Update: Testing the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medications in Patients With HIV and Cancer [Phase 1]
Phase 1 trial evaluating the addition of pembrolizumab to standard antiretroviral therapy in HIV-positive patients with cancer. The study ha…