Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-08-15Clinical Trial Update: PRIME_LUNG: Primary Radiotherapy In MEtastatic Lung Cancer - A Pilot Study [Phase 1]
An ongoing Phase 1 pilot trial (PRIME_LUNG) is evaluating primary radiotherapy in metastatic non-small cell lung cancer. The study is curren…
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CLINICAL_TRIALS trial_result · 2024-08-14Clinical Trial Update: FLARE RT for Patients With Stage IIB-IIIB Non-small Cell Lung Cancer: Personalizing Radiation Therapy Using PET/CT and SPECT/CT Imaging [Phase 2]
Phase 2 trial evaluating FLARE RT personalized radiation therapy for stage IIB-IIIB non-small cell lung cancer using PET/CT and SPECT/CT ima…
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CLINICAL_TRIALS research · 2024-08-14Clinical Trial Update: Neoadjuvant HS-10296 (Almonertinib) Therapy for Potential Resectable Stage III EGFR Mutation-Positive Non-small Cell Lung Cancer [Phase 2]
A Phase 2 neoadjuvant trial is evaluating almonertinib (HS-10296) for potentially resectable stage III EGFR-mutant non-small cell lung cance…
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CLINICAL_TRIALS trial_result · 2024-08-13Clinical Trial Update: Pembrolizumab + Imprime PGG for Metastatic Non-small Cell Lung Cancer After Progression on First-Line Therapy: Big Ten Cancer Research Consortium BTCRC-LUN15-017 [Phase 1, Phase 2]
Phase 1/2 study evaluating pembrolizumab with Imprime PGG in metastatic non-small cell lung cancer after progression on first-line therapy; …
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CLINICAL_TRIALS trial_result · 2024-08-13Clinical Trial Update: Real-world Data on Stage III NSCLC Patients Treated With Durvalumab After Chemoradiotherapy in Asia Area (PACIFIC AA)
Real-world data from a completed clinical trial program examining durvalumab after chemoradiotherapy in Asian stage III non-small cell lung …
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CLINICAL_TRIALS research · 2024-08-12Clinical Trial Update: Dietary Intervention for NSCLC Patients Treated With ICI [NA]
A clinical trial evaluating a dietary intervention in patients with non-small cell lung cancer who are treated with immune checkpoint inhibi…
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CLINICAL_TRIALS trial_result · 2024-08-09Clinical Trial Update: Toripalimab Combined With Double Platinum-based Chemotherapy for Initially Unresectable NSCLC [Phase 2]
Phase 2 trial results on toripalimab combined with double platinum-based chemotherapy for initially unresectable advanced non-small cell lun…
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CLINICAL_TRIALS trial_result · 2024-08-09Clinical Trial Update: AST-VAC2 Vaccine in Patients With Non-small Cell Lung Cancer [Phase 1]
Phase 1 results update for AST-VAC2 vaccine in patients with advanced non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2024-08-09Clinical Trial Update: SBRT Combined With Avelumab (Anti-PD-L1) for Management of Early Stage Non-Small Cell Lung Cancer (NSCLC) [Phase 1, Phase 2]
A phase 1/2 trial evaluating SBRT combined with Avelumab for non-small cell lung cancer was terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2024-08-09Clinical Trial Update: A Study Evaluating the Safety, Pharmacokinetics, and Preliminary Efficacy of Orally Administered SM08502 Combined With Hormonal Therapy or Chemotherapy in Subjects With Advanced Solid Tumors [Phase 1]
Phase 1 study evaluating the safety, pharmacokinetics, and preliminary efficacy of the oral SM08502 with hormonal therapy or chemotherapy in…
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CLINICAL_TRIALS research · 2024-08-09Clinical Trial Update: Alectinib in Neo-adjuvant Treatment of Stage III NSCLC [Phase 2]
Phase 2 trial evaluating neoadjuvant alectinib for stage III non-small cell lung cancer. The study is currently active but not recruiting.
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CLINICAL_TRIALS research · 2024-08-09Clinical Trial Update: Improving Osimertinib Exposure and Cost-effectiveness Using Pharmacokinetic Boosting With Cobicistat [Phase 4]
A Phase 4 clinical trial from Maastricht University Medical Center will evaluate boosting osimertinib exposure with cobicistat to improve dr…
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CLINICAL_TRIALS research · 2024-08-09Clinical Trial Update: Prognostic Value of Combined Approach Based on KEAP1/NFE2L2 Mutations and Pre-therapeutic FDG-PET/CT Radiomic Analysis in Advanced Non-small-cell Lung Cancer PDL1 ≥ 50% Treated With Pembrolizumab (PEMBROMIC)
This clinical trial update evaluates whether a combined KEAP1/NFE2L2 mutation profile and pre-treatment FDG-PET/CT radiomic analysis can pro…
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CLINICAL_TRIALS research · 2024-08-09Clinical Trial Update: ERectile Dysfunctions, gOnadotoxicity and Sexual Health Assessment in Men With Lung Cancer
Clinical trial update investigating erectile dysfunction, gonadotoxicity, and sexual health in men with non-small cell lung cancer (Stage IV…
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CLINICAL_TRIALS trial_result · 2024-08-09Clinical Trial Update: Study to IDEntify Patients With Advanced/Metastatic Non Small Cell Lung Cancer (NSCLC) and ALK and ROS1 Translocation and to Establish Their Therapeutic Management (IDEALK&ROS)
This completed clinical trial (IDEALK&ROS) identifies patients with advanced/metastatic non-small cell lung cancer who harbor ALK or ROS1 tr…
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CLINICAL_TRIALS withdrawal · 2024-08-09Clinical Trial Update: An Exploratory Clinical Study of Adebelimumab in Combination With Famitinib and Chemotherapy in Patients With NSCLC [Phase 2]
Phase 2 exploratory trial exploring Adebelimumab with Famitinib and chemotherapy for non-small cell lung cancer was withdrawn. Sponsor: Jian…
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CLINICAL_TRIALS research · 2024-08-09Clinical Trial Update: Surveillance With PET/CT and Liquid Biopsies of Stage I-III Lung Cancer Patients After Completion of Definitive Therapy [NA]
This clinical trial update describes surveillance using PET/CT scans and liquid biopsies for stage I-III non-small cell lung cancer after de…
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CLINICAL_TRIALS trial_result · 2024-08-07Clinical Trial Update: Efficacy and Safety of Concurrent Chemoradiotherapy With Oral Vinorelbine in Patients With Non-small Cell Lung Cancer [Phase 2]
This Phase 2 trial update evaluates the efficacy and safety of concurrent chemoradiotherapy using oral vinorelbine in patients with non-smal…
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CLINICAL_TRIALS trial_result · 2024-08-07Clinical Trial Update: Trial of Chidamide in Combination With Envafolimab in Patients With PD-1 Inhibitor Resistant Advanced NSCLC. [Phase 2]
Phase 2 trial evaluating chidamide in combination with envafolimab for PD-1 inhibitor-resistant advanced non-small cell lung cancer has comp…
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CLINICAL_TRIALS research · 2024-08-07Clinical Trial Update: Fecal Microbial Transplantation Non-Small Cell Lung Cancer and Melanoma [Phase 2]
Clinical trial update for a Phase 2 study evaluating fecal microbiota transplantation in metastatic non-small cell lung cancer and advanced …
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CLINICAL_TRIALS research · 2024-08-07Clinical Trial Update: Prediction of Mediastinal Station IV Lymph Node Metastasis in Non-small Cell Lung Cancer
This trial, sponsored by Qilu Hospital of Shandong University, aims to predict mediastinal station IV lymph node metastasis in non-small cel…
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CLINICAL_TRIALS other · 2024-08-07Clinical Trial Update: A Study of BPI-7711 Capsule in Non-small Cell Lung Cancer Patients [Phase 3]
The update confirms a Phase 3 study of BPI-7711 capsules for non-small cell lung cancer by Beta Pharma Shanghai is active but not recruiting…
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CLINICAL_TRIALS trial_result · 2024-08-07Clinical Trial Update: An Open-label, Uncontrolled Study of ONO-4578 and ONO-4538 in Combination With Standard-of-care Docetaxel and Ramucirumab as Second-line Therapy in Patients With Advanced or Recurrent Non-small Cell Lung Cancer [Phase 1]
An open-label Phase 1 study evaluates ONO-4578 and ONO-4538 in combination with standard-of-care docetaxel and ramucirumab as second-line th…
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CLINICAL_TRIALS trial_result · 2024-08-06Clinical Trial Update: Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Relapsed or Refractory Advanced Non-Small Cell Lung Cancer With an FGFR Alteration [Phase 2]
A Phase 2 study evaluated the efficacy and safety of pemigatinib in participants with relapsed or refractory advanced non-small cell lung ca…
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CLINICAL_TRIALS trial_result · 2024-08-06Clinical Trial Update: A Study of Osimertinib With or Without Chemotherapy as 1st Line Treatment in Patients With Mutated Epidermal Growth Factor Receptor Non-Small Cell Lung Cancer (FLAURA2) [Phase 3]
Phase 3 trial FLAURA2 compares osimertinib with or without chemotherapy as first-line treatment for EGFR-mutated non-small cell lung cancer;…