Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-11-18Clinical Trial Update: Neoadjuvant Toripalimab for Clinically Stage II-IIIB Resectable Non-small Cell Lung Cancer with EGFR Mutation and PD-L1 Positive Expression [Phase 2]
Phase 2 neoadjuvant trial of toripalimab for clinically stage II-IIIB resectable non-small cell lung cancer with EGFR mutation and PD-L1 pos…
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CLINICAL_TRIALS trial_result · 2024-11-18Clinical Trial Update: Evaluation of Clinical Performance and IVD Test of LifeOS Digital PCR Liquid Biopsy Kits for EGFR T790M Mutation
This clinical trial is evaluating the clinical performance of LifeOS Digital PCR Liquid Biopsy Kits for detecting the EGFR T790M mutation in…
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FDA approval · 2024-11-15FDA Approved: PEMRYDI RTU — Supplemental Application (Amneal Pharmaceuticals LLC)
The FDA approved a supplemental application for PEMRYDI RTU, a ready-to-use formulation of pemetrexed disodium, developed by Amneal Pharmace…
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CLINICAL_TRIALS trial_result · 2024-11-15Clinical Trial Update: A Phase 1 Study of Pegilodecakin (LY3500518) in Participants With Advanced Solid Tumors [Phase 1]
Phase 1 study of Pegilodecakin (LY3500518) in patients with advanced solid tumors has completed, spanning multiple indications including mel…
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CLINICAL_TRIALS research · 2024-11-15Clinical Trial Update: Phase 1a and Phase 2 Study for Safety, Preliminary Efficacy, PK and PD of ST-067 [Phase 1, Phase 2]
Phase 1a/Phase 2 study evaluating safety, preliminary efficacy, PK and PD of ST-067 in various cancers; currently recruiting.
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CLINICAL_TRIALS research · 2024-11-15Clinical Trial Update: Real-world Study of Local Therapy Changes During 1L Lorlatinib in Unresectable ALK+ NSCLC
Real-world study examining how local therapy decisions change during first-line lorlatinib treatment for unresectable ALK-positive non-small…
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CLINICAL_TRIALS research · 2024-11-15Clinical Trial Update: A Single-Arm, Phase Ⅰb Study of Golidocitinib Combined With Anti-PD-1 for the Treatment of Previously Treated NSCLC [Phase 1, Phase 2]
Phase 1b/Phase 2 single-arm trial evaluating golidocitinib in combination with an anti-PD-1 agent for previously treated non-small cell lung…
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CLINICAL_TRIALS trial_result · 2024-11-14Clinical Trial Update: A Dose Escalation Study of ASP8273 in Subjects With Non-Small-Cell Lung Cancer (NSCLC) Who Have Epidermal Growth Factor Receptor (EGFR) Mutations [Phase 1]
A Phase 1 dose-escalation study of ASP8273 in patients with non-small cell lung cancer harboring EGFR mutations has completed.
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CLINICAL_TRIALS research · 2024-11-14Clinical Trial Update: Neoadjuvant Chemotherapy Sequentially Combined with Sintilimab in Resectable EGFR-Mutant NSCLC [Phase 2]
A Phase 2 trial evaluating neoadjuvant chemotherapy sequentially combined with Sintilimab in resectable EGFR-mutant non-small cell lung canc…
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CLINICAL_TRIALS trial_result · 2024-11-14Clinical Trial Update: An Open Study of ASP8273 in Patients With Non-Small-Cell Lung Cancer (NSCLC) Who Have Epidermal Growth Factor Receptor (EGFR) Mutations [Phase 1, Phase 2]
This update indicates that the Phase 1/Phase 2 trial of ASP8273 in EGFR-mutant non-small cell lung cancer has been terminated.
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CLINICAL_TRIALS trial_result · 2024-11-13Clinical Trial Update: Study to Evaluate the Safety and Efficacy of Serplulimab Plus Bevacizumab and Chemotherapy in NSCLC Patients With Brain Metastases [Phase 2, Phase 3]
Phase 2/3 study evaluating the safety and efficacy of serplulimab plus bevacizumab and chemotherapy in non-small cell lung cancer patients w…
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CLINICAL_TRIALS trial_result · 2024-11-13Clinical Trial Update: Basket Study of Tucatinib and Trastuzumab in Solid Tumors With HER2 Alterations [Phase 2]
Phase 2 basket trial evaluating tucatinib in combination with trastuzumab across HER2-altered solid tumors, with results posted for several …
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CLINICAL_TRIALS research · 2024-11-13Clinical Trial Update: Perioperative Treatment Outcomes of Early NSCLC
This document provides a clinical trial update on perioperative treatment outcomes for early non-small cell lung cancer. Enrollment is by in…
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CLINICAL_TRIALS research · 2024-11-12Clinical Trial Update: A Multicenter, Single-arm, Open-label Study Evaluating the Safety and Efficacy of AK112 Combined With Chemotherapy as First-line Treatment for Non-squamous NSCLC Patients With BRAIN Metastases and Negative Driver Genes (IVO BRAIN) [Phase 2]
A multicenter, single-arm Phase 2 trial evaluating AK112 in combination with chemotherapy as first-line treatment for patients with non-squa…
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CLINICAL_TRIALS research · 2024-11-12Clinical Trial Update: Personalized Neoantigen MRNA Vaccine Combined with Adebrelimab in Non-Small Cell Lung Cancer Patients [EARLY_Phase 1]
An early-phase 1 clinical trial evaluating a personalized neoantigen mRNA vaccine in combination with the PD-1 inhibitor adebrelimab for non…
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CLINICAL_TRIALS research · 2024-11-12Clinical Trial Update: Lorlatinib as Neoadjuvant Treatment in Stage IB-IIIB ALK-rearranged Non-Small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial update evaluating lorlatinib as neoadjuvant therapy for stage IB-IIIB ALK-rearranged non-small cell lung cancer; th…
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CLINICAL_TRIALS research · 2024-11-12Clinical Trial Update: A Study of SHR-A2102 in Combination With Adebrelimab and SHR-8068 in Subjects With Locally Advanced or Metastatic Non-Small Cell Lung Cancer [Phase 1, Phase 2]
Clinical trial update for SHR-A2102 in combination with Adebrelimab and SHR-8068 for locally advanced or metastatic non-small cell lung canc…
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CLINICAL_TRIALS research · 2024-11-12Clinical Trial Update: AI-guided Prognostication and Cranial Radiotherapy Optimization in EGFR-TKI-treated Non-small Cell Lung Cancer Patients With Baseline Brain Metastases
An ongoing study from Fudan University evaluating AI-guided prognostication and cranial radiotherapy optimization in EGFR-TKI–treated patien…
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CLINICAL_TRIALS other · 2024-11-12Clinical Trial Update: Managed Access Program Cohort Treatment Plan CTMT212X2002I to Provide Access to Trametinib and Dabrafenib Combination Therapy for Patients With BRAF V600 Mutation-positive Advanced Non-Small Cell Lung Cancer
Novartis is offering access to the trametinib and dabrafenib combination through a managed access program for patients with BRAF V600 mutati…
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CLINICAL_TRIALS trial_result · 2024-11-08Clinical Trial Update: Long Term Safety Observation of Crizotinib in Chinese NSCLC Population [Phase 4]
A Phase 4 long-term safety observation of crizotinib in Chinese patients with ALK- or ROS1-positive non-small cell lung cancer has been term…
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CLINICAL_TRIALS trial_result · 2024-11-08Clinical Trial Update: Study to Access Safety of Durvalumab in Indian Adult Patients With Locally Advanced NSCLC [Phase 4]
Phase 4 study assessing the safety of durvalumab in Indian adults with unresectable non-small cell lung cancer. The study has completed and …
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CLINICAL_TRIALS trial_result · 2024-11-07Clinical Trial Update: TEIPP Immunotherapy in Patients With NSCLC [Phase 1, Phase 2]
This clinical trial update indicates completion of Phase 1 and Phase 2 testing of TEIPP immunotherapy in patients with non-small cell lung c…
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CLINICAL_TRIALS research · 2024-11-07Clinical Trial Update: Transbroncheal Novel PDT Peripheral Lung Tumor Ablation With 5-ALA [NA]
This clinical trial aims to evaluate transbronchial photodynamic therapy using 5-ALA for peripheral lung tumors; the trial is not yet recrui…
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CLINICAL_TRIALS trial_result · 2024-11-07Clinical Trial Update: Phase 1 Dose Escalation and Expansion to Evaluate AROG4-01 in Patients With Advanced Solid Tumors [Phase 1]
This Phase 1 update describes the dose-escalation and expansion study of AROG4-01 in patients with advanced solid tumors, including mesothel…
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CLINICAL_TRIALS trial_result · 2024-11-07Clinical Trial Update: Determination of Peripheral Immune Cell Activity During Treatment With Either Surgery or Radiotherapy in Patients With Early Stage NSCLC [NA]
This clinical trial update reports the completion of a study evaluating peripheral immune cell activity in patients with early-stage non-sma…