Non-small Cell Lung Cancer

CLINICAL_TRIALS trial_result · 2017-06-23

Clinical Trial Update: Bortezomib and Pemetrexed Disodium in Treating Patients With Advanced Non-Small Cell Lung Cancer or Other Solid Tumors [Phase 1, Phase 2]

Phase 1/2 trial investigating bortezomib with pemetrexed disodium in advanced non-small cell lung cancer and other solid tumors; completed w…

CLINICAL_TRIALS trial_result · 2017-06-23

Clinical Trial Update: Whole-Brain Radiation Therapy and Pemetrexed in Treating Patients With Brain Metastases From Non-Small Cell Lung Cancer [Phase 2]

Phase 2 trial evaluating whole-brain radiation therapy plus pemetrexed for brain metastases from non-small cell lung cancer; the study was t…

CLINICAL_TRIALS trial_result · 2017-06-22

Clinical Trial Update: Erlotinib Treatment Beyond Progression in EGFR Mutant NSCLC [Phase 2]

A Phase 2 clinical trial examining Erlotinib treatment beyond progression in EGFR-mutant non-small cell lung cancer has completed.

CLINICAL_TRIALS trial_result · 2017-06-21

Clinical Trial Update: A Study to Evaluate the Efficacy of Brigatinib (AP26113) in Participants With Anaplastic Lymphoma Kinase (ALK)-Positive, Non-small Cell Lung Cancer (NSCLC) Previously Treated With Crizotinib [Phase 2]

Phase 2 trial evaluating Brigatinib in ALK-positive NSCLC patients previously treated with crizotinib has completed with results posted in 2…

CLINICAL_TRIALS trial_result · 2017-06-19

Clinical Trial Update: LUX-Lung 7: A Phase IIb Trial of Afatinib(BIBW2992) Versus Gefitinib for the Treatment of 1st Line EGFR Mutation Positive Adenocarcinoma of the Lung [Phase 2]

Phase IIb trial comparing afatinib to gefitinib as first-line treatment for EGFR mutation-positive adenocarcinoma of the lung has completed …

CLINICAL_TRIALS trial_result · 2017-06-19

Clinical Trial Update: Combination Chemotherapy, Bev, RT, and Erlotinib in Treating Patients With Stage III Non-Small Cell Lung Cancer [Phase 1, Phase 2]

A completed Phase 1/2 clinical trial evaluating a combination of chemotherapy, bevacizumab, radiation therapy, and erlotinib in patients wit…

CLINICAL_TRIALS trial_result · 2017-06-14

Clinical Trial Update: Ruxolitinib in Combination With Pemetrexed/Cisplatin in Non Small Cell Lung Cancer [Phase 2]

Phase 2 trial evaluating ruxolitinib with pemetrexed/cisplatin in non-small cell lung cancer has been terminated; results posted in 2017.

CLINICAL_TRIALS trial_result · 2017-06-14

Clinical Trial Update: Vorinostat, Paclitaxel, and Radiation Therapy in Treating Patients Unable to Tolerate Cisplatin With Stage III Non-Small Lung Cancer That Cannot Be Removed By Surgery [Phase 1, Phase 2]

This Phase 1/2 trial evaluated a vorinostat/paclitaxel/radiation therapy regimen for patients with stage III non-small cell lung cancer who …

CLINICAL_TRIALS trial_result · 2017-06-14

Clinical Trial Update: Microwave Ablation in the Treatment of Stage I Non Small Cell Lung Cancer [Phase 3]

Phase 3 clinical trial update examining microwave ablation for stage I non-small cell lung cancer.

CLINICAL_TRIALS trial_result · 2017-06-12

Clinical Trial Update: Ph II Adjuvant Carboplatin/Docetaxel in Curatively Resected Stage I-IIIA NSCLC [Phase 2]

Phase II trial evaluating adjuvant carboplatin and docetaxel in curatively resected stage I-IIIA non-small cell lung cancer. Results were po…

CLINICAL_TRIALS trial_result · 2017-06-09

Clinical Trial Update: Ph II of Vinflunine and Cetuximab in Second Line Treatment of NSCLC [Phase 2]

Phase II trial of vinflunine in combination with cetuximab for second-line non-small cell lung cancer was terminated, with results posted in…

CLINICAL_TRIALS trial_result · 2017-06-08

Clinical Trial Update: Nintedanib in Treating Patients With Advanced Non-Small Cell Lung Cancer Who Have Failed Up to Two Previous Chemotherapy Regimens [Phase 2]

Phase 2 trial evaluating nintedanib in patients with advanced non-small cell lung cancer who progressed after up to two prior chemotherapy r…

CLINICAL_TRIALS trial_result · 2017-06-07

Clinical Trial Update: Safety and Pharmacokinetics of Escalating Doses of DNIB0600A in Participants With Non-Small Cell Lung Cancer (NSCLC) and Platinum Resistant Ovarian Cancer [Phase 1]

Phase 1 trial update evaluating the safety and pharmacokinetics of escalating doses of DNIB0600A in participants with non-small cell lung ca…

CLINICAL_TRIALS trial_result · 2017-06-06

Clinical Trial Update: Erlotinib With or Without Hydroxychloroquine in Chemo-Naive Advanced NSCLC and (EGFR) Mutations [Phase 2]

Phase 2 trial evaluating erlotinib with or without hydroxychloroquine in chemo-naive advanced non-small cell lung cancer with EGFR mutations…

CLINICAL_TRIALS trial_result · 2017-06-06

Clinical Trial Update: Study Evaluating the Addition of Fulvestrant to Erlotinib in Stage IIIB/IV Non-Small Cell Lung Cancer [Phase 2]

Phase 2 study evaluating the addition of fulvestrant to erlotinib in stage IIIB/IV non-small cell lung cancer was terminated; results were p…

CLINICAL_TRIALS trial_result · 2017-06-02

Clinical Trial Update: A Randomized Phase II Study of SUBATM-itraconazole in Patients With Untreated Squamous NSCLC. [Phase 2]

A randomized Phase II study of SUBATM-itraconazole in untreated metastatic non-small cell lung cancer was terminated; results posted in 2017…

CLINICAL_TRIALS trial_result · 2017-05-31

Clinical Trial Update: Observational Study to Evalute the Efficacy and Safety of Avastin (Bevacizumab) in Addition to Platinum-Based Chemotherapy for First-Line Treatment of Participants With Non-Small Cell Lung Cancer

This update reports the completion of an observational study evaluating Avastin (bevacizumab) added to platinum-based chemotherapy as first-…

CLINICAL_TRIALS trial_result · 2017-05-30

Clinical Trial Update: Gefitinib, Docetaxel, and Radiation Therapy in Treating Patients With Stage III Non-Small Cell Lung Cancer [Phase 1]

This Phase 1 clinical trial updates the safety and feasibility of combining gefitinib, docetaxel, and radiation therapy for patients with st…