Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-07-07Clinical Trial Update: A Phase III Study to Assess the Efficacy and Safety of Almonertinib Versus Platinum-based Chemotherapy as First-line Therapy in Patients With Locally Advanced or Metastatic NSCLC Harbouring Uncommon EGFR Mutation [Phase 3]
Phase III study comparing almonertinib to platinum-based chemotherapy as first-line therapy in locally advanced or metastatic non-small cell…
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CLINICAL_TRIALS trial_result · 2021-07-07Clinical Trial Update: Effects of Single Agent Niraparib and Niraparib Plus Programmed Cell Death-1 (PD-1) Inhibitors in Non-Small Cell Lung Cancer Participants [Phase 2]
Phase 2 trial update examining single-agent niraparib and niraparib plus PD-1 inhibitors in non-small cell lung cancer has completed with re…
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CLINICAL_TRIALS trial_result · 2021-07-07Clinical Trial Update: Combination of Almonertinib and Concurrent Chemoradiotherapy in Unresectable Stage III NSCLC [Phase 2]
Phase 2 study evaluating the combination of almonertinib with concurrent chemoradiotherapy in unresectable stage III non-small cell lung can…
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CLINICAL_TRIALS trial_result · 2021-07-01Clinical Trial Update: A Volume, Motion, and Anatomically Adaptive Approach to Photon and Proton Beam Radiotherapy [NA]
Clinical trial update describing an adaptive radiotherapy approach using photon and proton beams; results posted after completion.
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CLINICAL_TRIALS trial_result · 2021-06-29Clinical Trial Update: Camrelizumab Plus Apatinib for Advanced Non-Squamous NSCLC Previously Treated With First-Line Immunotherapy [Phase 2]
Phase 2 trial evaluating camrelizumab in combination with apatinib for advanced non-squamous non-small cell lung cancer previously treated w…
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CLINICAL_TRIALS trial_result · 2021-06-28Clinical Trial Update: Neoadjuvant Immunotherapy With Chemotherapy for Stage I-IIIB Non-Small Cell Lung Cancer Patients [Phase 2]
Phase 2 trial update on neoadjuvant immunotherapy combined with chemotherapy for stage I-IIIB non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2021-06-23Clinical Trial Update: A Study Comparing the Efficacy and Safety Between IBI308 and Docetaxel in Patients With Advanced or Metastatic NSCLC [Phase 3]
Phase 3 trial comparing IBI308 versus Docetaxel in advanced or metastatic non-small cell lung cancer has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-06-23Clinical Trial Update: Neoadjuvant Camrelizumab, Nab-paclitaxel and Carboplatin in Stage IB-IIIA NSCLC [Phase 2]
Phase 2 neoadjuvant trial evaluating camrelizumab with nab-paclitaxel and carboplatin in stage IB-IIIA non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2021-06-22Clinical Trial Update: Selumetinib in Patients Receiving Pemetrexed and Platinum-based Chemotherapy in Advanced or Metastatic KRAS Wildtype or Unknown Non-Squamous NSCLC [Phase 2]
Phase 2 trial evaluating selumetinib with pemetrexed and platinum in advanced/metastatic KRAS wildtype or unknown non-squamous non-small cel…
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CLINICAL_TRIALS trial_result · 2021-06-16Clinical Trial Update: Study of Erlotinib With or Without Investigational Drug (U3-1287) in Subjects With Advanced Non-small Cell Lung Cancer [Phase 1, Phase 2]
Phase 1/2 trial evaluating erlotinib with or without investigational drug U3-1287 in advanced non-small cell lung cancer has completed, with…
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CLINICAL_TRIALS trial_result · 2021-06-15Clinical Trial Update: A Study of Napabucasin (BBI-608) Plus Weekly Paclitaxel Versus Weekly Paclitaxel Alone in Patients With Advanced, Previously Treated, Non-Squamous Non-Small Cell Lung Cancer [Phase 3]
Phase 3 trial evaluating napabucasin plus weekly paclitaxel versus paclitaxel alone in advanced previously treated non-squamous non-small ce…
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CLINICAL_TRIALS trial_result · 2021-06-15Clinical Trial Update: Radiation Therapy in Treating Patients With Stage I or Stage II Non-Small Cell Lung Cancer [Phase 2]
Phase 2 trial evaluating radiation therapy for stage I-II non-small cell lung cancer has completed; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-06-15Clinical Trial Update: Study of Efficacy and Safety of Nivolumab in Combination With EGF816 and of Nivolumab in Combination With INC280 in Patients With Previously Treated Non-small Cell Lung Cancer [Phase 2]
Phase 2 trial update exploring nivolumab in combination with EGF816 and with INC280 for previously treated non-small cell lung cancer; study…
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CLINICAL_TRIALS trial_result · 2021-06-10Clinical Trial Update: Study For Patients With NSCLC EGFR Mutations (Del 19 or L858R +/- T790M) [Phase 1, Phase 2]
Clinical trial update for NSCLC patients with EGFR mutations (Del 19 or L858R +/- T790M); study phases 1 and 2, terminated with results post…
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CLINICAL_TRIALS trial_result · 2021-06-09Clinical Trial Update: Pembrolizumab in First Line Treatment of Advanced NSCLC Patients With PD-L1 Low Tumors. [Phase 2]
Phase 2 trial update on pembrolizumab as first-line treatment for advanced NSCLC with low PD-L1 expression.
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CLINICAL_TRIALS trial_result · 2021-06-03Clinical Trial Update: Osimertinib Study in Indian Patients [Phase 4]
Phase 4 trial update of osimertinib in Indian patients with non-small cell lung cancer has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-06-02Clinical Trial Update: PRe-Operative Gefitinib in Resectable EGFR Mutation Positive Lung Cancer With Sector Sequencing for Biomarker Discovery [Phase 2]
Phase 2 clinical trial evaluating pre-operative gefitinib in resectable EGFR mutation-positive non-small cell lung cancer with sector sequen…
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CLINICAL_TRIALS trial_result · 2021-06-02Clinical Trial Update: Almonertinib Combined With Cerebral Radiation Treat Brain Metastases From EGFR Positive NSCLC [Phase 2]
Phase 2 trial evaluating almonertinib with cerebral radiation for brain metastases in EGFR-positive non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2021-05-24Clinical Trial Update: Pemetrexed in Maintenance in Patients With Impaired Renal Function, 2 Dose Calculation Strategies [Phase 4]
Phase 4 trial update evaluating pemetrexed in maintenance for patients with impaired renal function using two dose calculation strategies in…
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CLINICAL_TRIALS trial_result · 2021-05-18Clinical Trial Update: Aprepitant vs. Desloratadine in EGFR-TKIs Related Pruritus Treatment [Phase 2]
Phase 2 trial comparing aprepitant to desloratadine for pruritus related to EGFR-TKI therapy in non-small cell lung cancer has completed.
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CLINICAL_TRIALS trial_result · 2021-05-17Clinical Trial Update: A Study of Atezolizumab as Neoadjuvant and Adjuvant Therapy in Resectable Non-Small Cell Lung Cancer (NSCLC) - Lung Cancer Mutation Consortium (LCMC3) [Phase 2]
Phase 2 LCMC3 trial evaluating atezolizumab as neoadjuvant and adjuvant therapy in resectable non-small cell lung cancer has completed enrol…
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CLINICAL_TRIALS trial_result · 2021-05-13Clinical Trial Update: First Line Chemotherapy Treatment of Advanced Non-Small Cell Lung Cancer (NSCLC) [Phase 2]
Phase 2 trial update on first-line chemotherapy for advanced non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2021-05-13Clinical Trial Update: Study of Pemetrexed + Carboplatin + Bevacizumab + Enzastaurin Versus Pemetrexed + Carboplatin + Bevacizumab + Placebo in Participants With Non-Small Cell Lung Cancer Who Have Not Been Previously Treated With Chemotherapy [Phase 2]
A Phase 2 trial comparing pemetrexed/carboplatin/bevacizumab/enzastaurin versus pemetrexed/carboplatin/bevacizumab/placebo in previously unt…
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CLINICAL_TRIALS trial_result · 2021-05-13Clinical Trial Update: A Study of Enzastaurin and Erlotinib in Participants With Solid Tumors and Lung Cancer [Phase 1, Phase 2]
Phase 1/2 study evaluating enzastaurin plus erlotinib in solid tumors and non-small cell lung cancer has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-05-12Clinical Trial Update: Serial [18F]Thymidine (FLT)PET/CT as a Biomarker of Response in Pemetrexed Therapy for Non-Small Cell Lung Cancer [NA]
Clinical trial update on FLT-PET/CT as a biomarker of response for pemetrexed therapy in non-small cell lung cancer; study terminated with p…