Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-05-17Clinical Trial Update: A Study of Atezolizumab Compared With a Single-Agent Chemotherapy in Treatment Naïve Participants With Locally Advanced or Recurrent or Metastatic Non-Small Cell Lung Cancer Who Are Deemed Unsuitable For Platinum-Doublet Chemotherapy [Phase 3]
Phase 3 trial comparing atezolizumab to single-agent chemotherapy in treatment-naïve NSCLC patients unsuitable for platinum therapy complete…
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CLINICAL_TRIALS trial_result · 2023-05-16Clinical Trial Update: To Evaluate the Efficacy and Safety of TQB3728 Tablets in Sequential Maintenance of TQB2450 Injection Therapy in Patients After Sequential or Concurrent Chemoradiation for Locally Advanced Non-small Cell Lung Cancer. [Phase 1, Phase 2]
A Phase 1/2 trial evaluating the efficacy and safety of TQB3728 tablets following TQB2450 injection therapy as maintenance in locally advanc…
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CLINICAL_TRIALS trial_result · 2023-05-12Clinical Trial Update: Immunotherapy by Nivolumab for HIV+ Patients [Phase 2]
Phase 2 trial update evaluating immunotherapy with nivolumab in HIV-positive patients with metastatic or stage IIIB non-small cell lung canc…
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CLINICAL_TRIALS trial_result · 2023-05-10Clinical Trial Update: Study to Compare AMG 510 "Proposed INN Sotorasib" With Docetaxel in Non Small Cell Lung Cancer (NSCLC) (CodeBreak 200). [Phase 3]
Phase 3 trial comparing sotorasib (AMG 510) against docetaxel in KRAS G12C-mutated advanced/metastatic non-small cell lung cancer; results w…
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CLINICAL_TRIALS trial_result · 2023-05-10Clinical Trial Update: Study to Compare AMG 510 "Proposed INN Sotorasib" With Docetaxel in Non Small Cell Lung Cancer (NSCLC) (CodeBreak 200). [Phase 3]
Phase 3 trial comparing AMG 510 (sotorasib) with docetaxel in KRAS G12C-mutated advanced/metastatic non-small cell lung cancer has completed…
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CLINICAL_TRIALS trial_result · 2023-05-10Clinical Trial Update: Phase-II Trial of Induction Chemotherapy and Chemoradiotherapy Plus/Minus Durvalumab and Consolidation Immunotherapy in Patients With Resectable Stage III NSCLC. [Phase 2]
Phase II trial update exploring induction chemotherapy with chemoradiotherapy +/- durvalumab followed by consolidation immunotherapy in rese…
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CLINICAL_TRIALS trial_result · 2023-05-09Clinical Trial Update: A Phase III Trial of Neoadjuvant Sintilimab and Chemotherapy for NSCLC Harboring No Driver Mutations [Phase 3]
A Phase III trial evaluating neoadjuvant Sintilimab plus chemotherapy for non-small cell lung cancer without driver mutations is in progress…
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CLINICAL_TRIALS trial_result · 2023-05-08Clinical Trial Update: Sasanlimab (PF-06801591, PD-1 Inhibitor) in Participants With Advanced Malignancies [Phase 1, Phase 2]
Pfizer's PD-1 inhibitor sasanlimab (PF-06801591) is being studied in Phase 1/2 in adults with advanced cancers, including non-small-cell lun…
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CLINICAL_TRIALS trial_result · 2023-05-08Clinical Trial Update: Disitamab Vedotin Combined Therapy for Locally Advanced or Metastatic NSCLC Patients With HER2 Alterations [Phase 2]
Phase 2 trial update investigating disitamab vedotin in combination therapy for locally advanced or metastatic non-small cell lung cancer wi…
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CLINICAL_TRIALS trial_result · 2023-05-03Clinical Trial Update: Toripalimab in Combination With Chemotherapy and Antiangiogenic Agents in Patients With Non-Small Cell Lung Cancer After Failure of Immunotherapy (PD-1/L1 Inhibitors) [Phase 2]
Phase 2 trial evaluating toripalimab in combination with chemotherapy and antiangiogenic agents for non-small cell lung cancer after failure…
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CLINICAL_TRIALS trial_result · 2023-05-01Clinical Trial Update: G1T38, a CDK 4/6 Inhibitor, in Combination With Osimertinib in EGFR-Mutant Non-Small Cell Lung Cancer [Phase 1, Phase 2]
Phase 1/2 trial evaluating G1T38 in combination with osimertinib for EGFR-mutant non-small cell lung cancer has completed with results poste…
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CLINICAL_TRIALS trial_result · 2023-05-01Clinical Trial Update: Hippocampal-Sparing Prophylactic Cranial Irradiation in Pathologically Nodal Positive Non-Small-Cell Lung Cancer [Phase 2, Phase 3]
Phase 2/3 trial evaluating hippocampal-sparing prophylactic cranial irradiation in patients with pathologically nodal positive non-small-cel…
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CLINICAL_TRIALS trial_result · 2023-04-25Clinical Trial Update: Ramucirumab and Pembrolizumab Versus Standard of Care in Treating Patients With Stage IV or Recurrent Non-small Cell Lung Cancer (A Lung-MAP Non-Match Treatment Trial) [Phase 2]
Phase 2 Lung-MAP non-match trial evaluating ramucirumab plus pembrolizumab versus standard of care in stage IV or recurrent non-small cell l…
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CLINICAL_TRIALS trial_result · 2023-04-25Clinical Trial Update: KN046 Plus Lenvatinib in Subject With Advanced Non-Small Cell Lung Cancer in the Failure of Anti-PD-(L)1 Agent [Phase 2, Phase 3]
A clinical trial evaluating KN046 plus lenvatinib in advanced non-small cell lung cancer after failure of anti-PD-(L)1 therapy has been term…
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CLINICAL_TRIALS trial_result · 2023-04-24Clinical Trial Update: Radiation and Immune Checkpoints Blockade in Metastatic NSCLC (BMS # CA209-632) [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating radiation combined with immune checkpoint blockade in metastatic non-small cell lung cancer was termin…
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CLINICAL_TRIALS trial_result · 2023-04-21Clinical Trial Update: Aumolertinib Adjuvant Therapy of Resectable Stage I EGFRm+ NSCLC With High-grade Patterns [Phase 2]
A phase 2 clinical trial exploring adjuvant aumolertinib after resection for resectable stage I EGFRm+ non-small cell lung cancer with high-…
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CLINICAL_TRIALS trial_result · 2023-04-21Clinical Trial Update: Non Small Cell Lung Cancer Trial of Durvalumab and Tremelimumab in Advanced Epidermal Growth Factor Receptor (EGFR) Mutant Disease. [Phase 2]
Phase 2 trial evaluating durvalumab and tremelimumab in adults with EGFR-mutant advanced non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2023-04-21Clinical Trial Update: Evolution of the Heart Function When Monitoring Immunotherapies Anti-cancerous Inhibiting PD-1 [Phase 4]
Phase 4 clinical trial update evaluating heart function during PD-1–inhibiting immunotherapy in melanoma and non-small cell cancer patients.
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CLINICAL_TRIALS trial_result · 2023-04-14Clinical Trial Update: Furmonertinib in Patients With Leptomeningeal Metastases Associated With EGFR Mutated NSCLC [Phase 2]
Phase 2 clinical trial update for furmonertinib in patients with leptomeningeal metastases associated with EGFR-mutated non-small cell lung …
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CLINICAL_TRIALS trial_result · 2023-04-13Clinical Trial Update: A Study of Atezolizumab in Combination With Bevacizumab in Patients With EGFR Mutation Positive Stage IIIB-IV Non-Squamous Non-Small Cell Lung Cancer [Phase 2]
A Phase 2 study evaluating the combination of atezolizumab and bevacizumab in EGFR mutation-positive stage IIIB-IV non-squamous non-small ce…
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CLINICAL_TRIALS trial_result · 2023-04-13Clinical Trial Update: Aumolertinib Combined Intrathecal Chemotherapy for Leptomeningeal Metastasis From EGFR-Mutated NSCLC and Prognostic Value of Dynamic Changes in cfDNA Profiles [Phase 2]
A Phase 2 clinical trial evaluates aumolertinib combined with intrathecal chemotherapy for leptomeningeal metastasis in EGFR-mutated non-sma…
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CLINICAL_TRIALS trial_result · 2023-04-12Clinical Trial Update: Phase I/II Study of SY-5007, a RET Inhibitor, in Patients With RET-altered Advanced Solid Tumor [Phase 1, Phase 2]
Phase I/II clinical trial update for SY-5007, a RET inhibitor, in RET-altered advanced solid tumors including non-small cell lung cancer and…
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CLINICAL_TRIALS trial_result · 2023-04-11Clinical Trial Update: Molecular Profiling and Targeted Therapy for Advanced Non-Small Cell Lung Cancer, Small Cell Lung Cancer, and Thymic Malignancies [Phase 2]
A Phase 2 trial evaluating molecular profiling-guided targeted therapy across advanced non-small cell lung cancer, small cell lung cancer, a…
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CLINICAL_TRIALS trial_result · 2023-04-10Clinical Trial Update: A Phase Ib/II Clinical Trial to Evaluate the Safety and Efficacy of HLX208+HLX10 in NSCLC With BRAF V600E Mutation [Phase 1, Phase 2]
A Phase Ib/II trial evaluating the safety and efficacy of HLX208 plus HLX10 in non-small cell lung cancer with BRAF V600E mutation, currentl…
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CLINICAL_TRIALS trial_result · 2023-04-07Clinical Trial Update: Maintenance Chemotherapy Versus Consolidative Stereotactic Body Radiation Therapy (SBRT) Plus Maintenance Chemotherapy for Stage IV Non-Small Cell Lung Cancer (NSCLC): A Randomized Phase II Trial [Phase 2]
A randomized Phase II trial comparing maintenance chemotherapy alone versus maintenance chemotherapy plus consolidative SBRT for stage IV no…