Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-02-15Clinical Trial Update: Study of Pembrolizumab (MK-3475) vs Placebo for Participants With Non-small Cell Lung Cancer After Resection With or Without Standard Adjuvant Therapy (MK-3475-091/KEYNOTE-091) [Phase 3]
This update reports the completion and posted results from the Phase 3 MK-3475-091/KEYNOTE-091 trial comparing pembrolizumab to placebo as a…
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CLINICAL_TRIALS trial_result · 2024-02-15Clinical Trial Update: Metronomic Oral Vinorelbine Combination With Tislelizumab in EGFR/ALK-negative Advanced NSCLC [Phase 2]
Phase 2 clinical trial evaluating metronomic oral vinorelbine in combination with tislelizumab for EGFR/ALK-negative advanced non-small cell…
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CLINICAL_TRIALS trial_result · 2024-02-12Clinical Trial Update: A Study Of SY-3505 Versus Crizotinib In First Line Treatment Of Patients With ALK-Positive NSCLC [Phase 3]
Phase 3 trial comparing SY-3505 to crizotinib in first-line ALK-positive non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2024-02-09Clinical Trial Update: Osimertinib With or Without Savolitinib as 1L in de Novo MET+, EGFR+ NSCLC [Phase 2]
Phase 2 trial updating osimertinib with or without savolitinib as first-line in de novo MET-positive, EGFR-mutant non-small cell lung cancer…
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CLINICAL_TRIALS trial_result · 2024-02-08Clinical Trial Update: Safety and Efficacy of Capmatinib (INC280) Plus Pembrolizumab vs Pembrolizumab Alone in NSCLC With PD-L1≥ 50% [Phase 2]
Phase 2 trial evaluating capmatinib plus pembrolizumab versus pembrolizumab alone in non-small cell lung cancer with PD-L1 expression ≥50%; …
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CLINICAL_TRIALS trial_result · 2024-02-07Clinical Trial Update: Accelerated Radio-Immunotherapy for Lung Cancer [Phase 2]
Phase 2 clinical trial on accelerated radio-immunotherapy for stage III non-small cell lung cancer has completed.
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CLINICAL_TRIALS trial_result · 2024-02-07Clinical Trial Update: Safety of Pentoxifylline and Vitamin E With Stereotactic Ablative Radiotherapy (SABR) in Non-small Cell Lung Cancers [Phase 2]
Phase 2 trial update assessing safety of pentoxifylline and vitamin E with SABR in non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2024-02-06Clinical Trial Update: Study of Capmatinib and Spartalizumab/Placebo in Advanced NSCLC Patients With MET Exon 14 Skipping Mutations [Phase 2]
Phase 2 study evaluating Capmatinib with Spartalizumab or placebo in advanced MET exon 14 skipping NSCLC was terminated; results have been p…
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CLINICAL_TRIALS trial_result · 2024-02-06Clinical Trial Update: Treatment With BIBW 2992, Irreversible Inhibitor of EGFR and HER-2 in Non-small Cell Lung Cancer [Phase 2]
Phase 2 clinical trial update for BIBW 2992 (neratinib), an irreversible EGFR and HER-2 inhibitor, in non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2024-02-05Clinical Trial Update: A Study of Ramucirumab (LY3009806) or Necitumumab (LY3012211) Plus Osimertinib in Participants With Lung Cancer [Phase 1]
Phase 1 study evaluating ramucirumab or necitumumab plus osimertinib in non-small cell lung cancer has completed with results posted.
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CLINICAL_TRIALS trial_result · 2024-02-02Clinical Trial Update: OSE2101 Versus Chemotherapy in HLA-A2 Positive Patients With Advanced NSCLC After Immune Checkpoint Inhibitor Failure [Phase 3]
Phase 3 trial comparing OSE2101 to chemotherapy in HLA-A2 positive advanced NSCLC after immune checkpoint inhibitor failure was terminated; …
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CLINICAL_TRIALS trial_result · 2024-01-30Clinical Trial Update: Brief Title: Study of Efficacy and Safety of Canakinumab as Adjuvant Therapy in Adult Subjects With Stages AJCC/UICC v. 8 II-IIIA and IIIB (T>5cm N2) Completely Resected Non-small Cell Lung Cancer Acronym: CANOPY-A [Phase 3]
CANOPY-A is a Phase 3 trial evaluating canakinumab as adjuvant therapy for completely resected non-small cell lung cancer. The study was ter…
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CLINICAL_TRIALS trial_result · 2024-01-30Clinical Trial Update: Trastuzumab Deruxtecan in Participants With HER2-mutated Metastatic Non-small Cell Lung Cancer (NSCLC) [Phase 2]
Phase 2 trial results update for trastuzumab deruxtecan (Enhertu) in HER2-mutated metastatic non-small cell lung cancer; results have been p…
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CLINICAL_TRIALS trial_result · 2024-01-30Clinical Trial Update: Study to Evaluate Treatment Customized According to RAP80 and BRCA1 in Patients With Advanced Lung Carcinoma [Phase 3]
Phase 3 trial evaluating treatment tailored to RAP80 and BRCA1 in advanced non-small cell lung cancer with BRCA1 mutation; study terminated …
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CLINICAL_TRIALS trial_result · 2024-01-30Clinical Trial Update: Phase III Study of TY-9591 in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer (FLETEO) [Phase 3]
Phase III clinical trial update for TY-9591 in locally advanced or metastatic non-small cell lung cancer (NCT05382728) is currently recruiti…
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CLINICAL_TRIALS trial_result · 2024-01-23Clinical Trial Update: CHEckpoint Inhibition in Combination With an Immunoboost of External Beam Radiotherapy in Solid Tumors [Phase 2]
Phase 2 trial evaluating checkpoint inhibition in combination with external beam radiotherapy for solid tumors; study is completed.
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CLINICAL_TRIALS trial_result · 2024-01-23Clinical Trial Update: PROCLAIM-CX-2029: A Trial to Find Safe and Active Doses of an Investigational Drug CX-2029 for Patients With Solid Tumors or DLBCL [Phase 1, Phase 2]
Phase 1/2 trial update for CX-2029 in solid tumors and DLBCL completed; aims to identify safe and active dose levels.
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CLINICAL_TRIALS trial_result · 2024-01-18Clinical Trial Update: Osimertinib in Treating Participants With Stage I-IIIA EGFR-mutant Non-small Cell Lung Cancer Before Surgery [Phase 2]
Phase 2 trial evaluating osimertinib given before surgery in patients with stage I-IIIA EGFR-mutant non-small cell lung cancer. Results have…
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CLINICAL_TRIALS trial_result · 2024-01-17Clinical Trial Update: Study of Pemetrexed + Platinum Chemotherapy With or Without Pembrolizumab (MK-3475) in Adults With Tyrosine Kinase Inhibitor- (TKI)-Resistant Epidermal Growth Factor Receptor- (EGFR)-Mutated Metastatic Non-squamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-789/KEYNOTE-789) [Phase 3]
A Phase 3 trial evaluating pemetrexed plus platinum chemotherapy with or without pembrolizumab in adults with tyrosine kinase inhibitor–resi…
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CLINICAL_TRIALS trial_result · 2024-01-17Clinical Trial Update: Prospective Clinicogenomic Program [Phase 4]
A Phase 4 prospective clinicogenomic program in progress for non-small cell lung cancer and small-cell lung cancer has completed.
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CLINICAL_TRIALS trial_result · 2024-01-16Clinical Trial Update: M7824 With cCRT in Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) [Phase 2]
Phase 2 trial update for M7824 in unresectable stage III non-small cell lung cancer has been terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2024-01-12Clinical Trial Update: A Study of Avutometinib (VS-6766) + Defactinib in Recurrent KRAS G12V, Other KRAS and BRAF Non-Small Cell Lung Cancer [Phase 2]
Phase 2 trial evaluating avutometinib (VS-6766) in combination with defactinib in recurrent KRAS G12V, other KRAS and BRAF mutated non-small…
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CLINICAL_TRIALS trial_result · 2024-01-12Clinical Trial Update: Study to Compare the Effects of Repeated Doses of an Investigational New Drug and a Placebo on Appetite in Advanced Cancer and Anorexia [Phase 1]
Phase 1 study comparing repeated doses of an investigational drug versus placebo to assess effects on appetite in advanced cancer and anorex…
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CLINICAL_TRIALS trial_result · 2024-01-12Clinical Trial Update: Biodistribution and Safety of the PET Probes [18F]FPRGD2 and [18F]FPPRGD2 [EARLY_Phase 1]
Phase 1 trial update assessing biodistribution and safety of PET probes [18F]FPRGD2 and [18F]FPPRGD2 in cancer patients; results posted afte…
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CLINICAL_TRIALS trial_result · 2024-01-11Clinical Trial Update: Trial of Consolidation Pembrolizumab After Concurrent Chemotherapy and Proton Reirradiation for Thoracic Recurrences of Non-Small Cell Lung Cancer [Phase 2]
Phase 2 trial evaluating consolidation pembrolizumab after concurrent chemotherapy and proton reirradiation for thoracic recurrences of non-…