Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-04-12Clinical Trial Update: A Study to Investigate the Safety and Efficacy of GB1211 (a Galectin-3 Inhibitor) in Combination With Atezolizumab in Patients With Non-Small Cell Lung Cancer (NSCLC). [Phase 1, Phase 2]
Clinical trial investigating GB1211 with atezolizumab in non-small cell lung cancer is currently active and not recruiting, spanning Phase 1…
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CLINICAL_TRIALS trial_result · 2024-04-12Clinical Trial Update: Study of PF-07263689 in Participants With Selected Advanced Solid Tumors [Phase 1]
Phase 1 trial of PF-07263689 in selected advanced solid tumors was terminated with results posted.
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CLINICAL_TRIALS trial_result · 2024-04-11Clinical Trial Update: Dose Tapering and Early Discontinuation to InCreAse cosT-effectIveness Of Immunotherapy for NSCLC [Phase 3]
A Phase 3 trial investigating dose tapering and early discontinuation to increase cost-effectiveness of immunotherapy in non-small cell lung…
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CLINICAL_TRIALS trial_result · 2024-04-10Clinical Trial Update: A Single-arm Pilot Study of Tislelizumab Combined With Anlotinib in Patients With Advanced NSCLC With Driver-negative After Progression to Immunotherapy [Phase 4]
A single-arm pilot Phase 4 study evaluating tislelizumab plus anlotinib in advanced driver-negative non-small cell lung cancer after progres…
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CLINICAL_TRIALS trial_result · 2024-04-10Clinical Trial Update: Preoperative Neoadjuvant Immunotherapy Combined With Chemotherapy for Stage Ⅲ Unresectable Non-small Cell Lung Cancer [Phase 4]
A Phase 4 trial update evaluating preoperative neoadjuvant immunotherapy combined with chemotherapy for stage III unresectable non-small cel…
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CLINICAL_TRIALS trial_result · 2024-04-09Clinical Trial Update: D-0316 in Patients With EGFR Positive Non Small Cell Lung Cancer [Phase 2]
Phase 2 clinical trial update for D-0316 in patients with EGFR-positive non-small cell lung cancer (NSCLC) has completed.
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CLINICAL_TRIALS trial_result · 2024-04-09Clinical Trial Update: A Study of Avelumab in Combination With Axitinib In Non-Small Cell Lung Cancer (NSCLC) or Urothelial Cancer (Javelin Medley VEGF) [Phase 2]
Phase 2 study evaluating avelumab in combination with axitinib for non-small cell lung cancer or urothelial cancer has been terminated with …
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CLINICAL_TRIALS trial_result · 2024-04-05Clinical Trial Update: Study to Evaluate Clinical Real World Outcomes of Lorlatinib After Alectinib in ALK-Positive NSCLC Japanese Patients
A completed clinical trial evaluating real-world outcomes of lorlatinib after alectinib in ALK-positive non-small-cell lung cancer patients …
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CLINICAL_TRIALS trial_result · 2024-04-03Clinical Trial Update: Study of DS-1062a in Advanced or Metastatic Non-small Cell Lung Cancer With Actionable Genomic Alterations (TROPION-Lung05) [Phase 2]
Phase 2 study of DS-1062a in advanced or metastatic non-small cell lung cancer with actionable genomic alterations has completed and posted …
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CLINICAL_TRIALS trial_result · 2024-04-03Clinical Trial Update: A Study of Anti-PD-1 AK105 in Patients With Metastatic Squamous Non-small Cell Lung Cancer [Phase 3]
Phase 3 clinical trial for AK105 (anti-PD-1) in metastatic squamous non-small cell lung cancer has completed.
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CLINICAL_TRIALS trial_result · 2024-04-03Clinical Trial Update: A Study of Anti-PD-1 AK105 in Patients With Metastatic Nonsquamous Non-small Cell Lung Cancer [Phase 3]
Phase 3 trial of AK105 (anti-PD-1) in metastatic nonsquamous non-small cell lung cancer was terminated.
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CLINICAL_TRIALS trial_result · 2024-04-03Clinical Trial Update: Phase I/II Study of SBRT and GC4711 for Centrally Located or Large NSCLC [Phase 1, Phase 2]
Phase I/II study evaluating GC4711 with SBRT for centrally located or large non-small cell lung cancer was terminated, with results posted o…
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CLINICAL_TRIALS trial_result · 2024-04-02Clinical Trial Update: Pembrolizumab/Vibostolimab Coformulation (MK-7684A) or Pembrolizumab/Vibostolimab Coformulation Plus Docetaxel Versus Docetaxel for Metastatic Non Small Cell Lung Cancer (NSCLC) With Progressive Disease After Platinum Doublet Chemotherapy and Immunotherapy (MK-7684A-002, KEYVIBE-002) [Phase 2]
Phase 2 trial evaluating pembrolizumab/vibostolimab coformulation (MK-7684A), with or without docetaxel, versus docetaxel alone in metastati…
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CLINICAL_TRIALS trial_result · 2024-04-02Clinical Trial Update: HERTHENA-Lung01: Patritumab Deruxtecan in Subjects With Metastatic or Locally Advanced EGFR-mutated Non-Small Cell Lung Cancer [Phase 2]
Phase 2 trial update for patritumab deruxtecan in metastatic or EGFR-mutated non-small cell lung cancer; results have been posted.
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CLINICAL_TRIALS trial_result · 2024-04-02Clinical Trial Update: Anlotinib Combined With Penpulimab as Front-line Treatment in Advanced Non-small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial evaluating anlotinib combined with penpulimab as first-line therapy for advanced non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2024-04-02Clinical Trial Update: Natural Killer(NK) Cell Combined With Programmed Death-1(PD-1) Antibody as Second Line Therapy for Advanced Driver Mutation Negative Non-small Cell Lung Cancer [Phase 2]
Phase 2 trial evaluating a natural killer cell therapy combined with a PD-1 antibody as second-line treatment for advanced driver mutation-n…
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CLINICAL_TRIALS trial_result · 2024-04-02Clinical Trial Update: To Evaluate the Safety and Tolerability of Carbognilumab Combined With Chemotherapy as the First-line Treatment for Patients With KEAP1 Mutated Advanced or Postoperative Recurrent Non-small Cell Lung Cancer (NSCLC) [Phase 2]
Phase 2 trial evaluating the safety and tolerability of carbognilumab with chemotherapy as first-line treatment for KEAP1-mutated advanced o…
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CLINICAL_TRIALS trial_result · 2024-04-01Clinical Trial Update: A Study of Furmonertinib Combined With Chemotherapy in the Treatment of NSCLC With Leptomeningeal Metastasis [Phase 2]
A Phase 2 clinical trial evaluates furmonertinib in combination with chemotherapy for non-small cell lung cancer with leptomeningeal metasta…
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CLINICAL_TRIALS trial_result · 2024-03-29Clinical Trial Update: Tipifarnib in Advanced Squamous NSCLC With Oncogen HRAS MutAtionS [Phase 2]
Phase 2 trial of tipifarnib in advanced squamous non-small cell lung cancer with HRAS mutations has been terminated; results were posted in …
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CLINICAL_TRIALS trial_result · 2024-03-29Clinical Trial Update: Dose Escalation Study MORAb-066 Targeting Tissue Factor (TF)-Expressing Malignancies Including Breast, Pancreatic, Colorectal, NSCLC [Phase 1]
Phase 1 dose-escalation study of MORAb-066 targeting tissue factor-expressing malignancies, including breast, pancreatic, colorectal, and no…
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CLINICAL_TRIALS trial_result · 2024-03-28Clinical Trial Update: A Phase II/III Study of Adebrelimab in Combination With SHR-8068 and Chemotherapy in Advanced or Metastatic NSCLC Patients [Phase 2, Phase 3]
A Phase II/III clinical trial evaluating Adebrelimab in combination with SHR-8068 and chemotherapy for advanced or metastatic non-squamous n…
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CLINICAL_TRIALS trial_result · 2024-03-28Clinical Trial Update: Serplulimab Plus Bevacizumab and Chemotherapy for EGFR-mutant Metastatic NSCLC Patients After EGFR-TKI Treatment Failure [Phase 2]
Phase 2 trial evaluating serplulimab plus bevacizumab and chemotherapy for EGFR-mutant metastatic non-squamous non-small cell lung cancer af…
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CLINICAL_TRIALS trial_result · 2024-03-28Clinical Trial Update: Tusamitamab Ravtansine (SAR408701) in Combination With Ramucirumab or Ramucirumab and Pembrolizumab in Pretreated Patients With NSQ NSCLC (CARMEN-LC04) [Phase 2]
Phase 2 CARMEN-LC04 trial evaluating Tusamitamab Ravtansine with Ramucirumab, with or without Pembrolizumab, in pretreated metastatic non-sm…
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CLINICAL_TRIALS trial_result · 2024-03-27Clinical Trial Update: SABR-ATAC: A Trial of TGF-beta Inhibition and Stereotactic Ablative Radiotherapy for Early Stage Non-small Cell Lung Cancer [Phase 1, Phase 2]
Phase 1/2 trial evaluating TGF-beta inhibition combined with stereotactic ablative radiotherapy for early stage non-small cell lung cancer h…
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CLINICAL_TRIALS trial_result · 2024-03-27Clinical Trial Update: A Study of Trilaciclib Combined With Chemotherapy in the Treatment of Advanced NSCLC With Leptomeningeal Metastasis [Phase 2]
Phase 2 trial evaluating trilaciclib with chemotherapy for advanced non-small cell lung cancer with leptomeningeal metastasis.